PLOS ONE pulls malaria study for “inappropriate manipulation” of figures

PLOS OnePLOS ONE has retracted a malaria paper after an institutional investigation found evidence the authors had manipulated multiple figures.

According to the notice, the authors’ institution — the International Centre for Genetic Engineering and Biotechnology (ICGEB) in New Delhi, India — recommended the journal retract the paper.

Here’s the retraction notice, issued by PLOS ONE on June 30: Continue reading PLOS ONE pulls malaria study for “inappropriate manipulation” of figures

Five more retractions for biologist with funding ban brings total to six

Journal of Cell ScienceAn erstwhile cell biologist has retracted five papers published in the Journal of Cell Science (JCS), all of which had been flagged in a recent investigation by the U.S. Office of Research Integrity (ORI).

The investigation found John Pastorino, previously a cell biologist at Rowan University in New Jersey, guilty of doctoring more than 40 images, resulting in a five-year funding ban.

The probe identified eight papers co-authored by Pastorino, six of which had already received expressions of concern (EOC) — including all of the newly retracted JCS papers. Nataly Shulga is a co-author on all eight papers.

Last week, we reported on the first of the expected retractions of the flagged papers in the Journal of Biological Chemistry.

Here are the retraction notices, which are the same for all five JCS papers: Continue reading Five more retractions for biologist with funding ban brings total to six

Authors pull Mol Cell paper for “inappropriate manipulation” of data

Molecular CellThe authors of a Molecular Cell paper have retracted it due to issues with multiple figures — including one with evidence of “intentional misconduct.”

According to the authors’ institution, IMIM in Barcelona, all co-authors are aware of the retraction. The penultimate author — Antonio García de Herrerosretracted three papers in May from the Journal of Biological Chemistry for reusing images to represent different experiments, and recently corrected multiple figures in a Journal of Cell Science paper over “possible duplications and/or splices.”

Here’s the newest retraction notice: Continue reading Authors pull Mol Cell paper for “inappropriate manipulation” of data

Here’s why this lawyer defends scientists accused of misconduct

Paul S. Thaler
Paul S. Thaler

More scientists are trying to settle accusations of misconduct in court, a trend very familiar to Washington, DC-based lawyer Paul Thaler. Regular readers may recall the name of one of Thaler’s clients — Rakesh Kumar, a scientist at George Washington University who filed an $8 million lawsuit for how the school handled an investigation into his work. He’s also representing Bharat Aggarwal, the subject of an investigation at MD Anderson who has threatened to sue us (and logged his ninth retraction this week). For 25 years, Thaler has been representing scientists embroiled in misconduct proceedings. He spoke to us about his family’s highly pedigreed background in science, and why everyone deserves an advocate.  

Some of your clients have committed misconduct, but you still work to protect their reputations and even help them continue to do research. Why? 

Continue reading Here’s why this lawyer defends scientists accused of misconduct

Researcher committed misconduct “recklessly,” says investigation

American Journal of Physiology Renal PhsyiologyA physiology journal has retracted a paper after an institutional investigation found that portions of the work had been falsified by the first author.

According to the notice issued by the American Journal of Physiology – Renal Physiology (AJP), the last author initiated the investigation at the University of Houston in Texas, which found the first author — Mousa Abkhezr — to be guilty of falsifying and duplicating images. 

We’ve obtained a copy of the investigation report, which concluded that Abkhezr committed misconduct “recklessly,” and the paper must be retracted. Although the report noted that Abkhezr argued that the problems stemmed from an honest error, the investigation committee ruled that data from the retracted paper cannot be included in his doctoral thesis.

The last author told us there is a separate ongoing “academic honesty enquiry” into Abkhezr’s dissertation. 

Here’s the retraction notice: Continue reading Researcher committed misconduct “recklessly,” says investigation

Investigation raises questions about top cancer researcher’s work

Journal of Pathology

A prominent pancreatic cancer researcher has lost a meeting abstract and corrected a Nature paper following an institutional investigation.

Queen Mary University of London determined that, in an abstract by Thorsten Hagemann, “elements of the study summarised by this abstract are not reliable.” Hagemann has recently issued a correction to a 2014 Nature paper he co-authored, which also cited the Queen Mary University of London (QMUL) investigation, noting there was reason to question the provenance of the data.

Hagemann is currently the medical director of Immodulon Therapeutics, and has long been recognized for his work in the field, including a three-year grant of £180,000 from the Pancreatic Cancer Research Fund in 2013.

Here’s the retraction notice from the The Journal of Pathology, regarding an abstract from the 7th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland: Continue reading Investigation raises questions about top cancer researcher’s work

Two journals retracting papers from University of Malaya featuring widely criticized figures

The image that excited twitter: Figure 6 from the Scientific Reports paper
The image that excited Twitter

One journal has retracted a paper containing images that recently raised suspicions of obvious duplications, and another journal is planning to do the same.

Scientists first leveled accusations against the newly retracted paper in Scientific Reports, along with two others by the same researchers, earlier this month on Twitter. One other journal — PeerJ — has announced that it plans to retract one of the questioned papers, as well. The third paper, in Frontiers in Pharmacology, bears an expression of concern.

It was unusually quick action on the part of the journals, as well as the authors’ host institution, the University of Malaya, which announced last week the authors had manipulated figures in all three papers, along with one other.

Here’s today’s retraction notice from Scientific Reports for “Novel piperazine core compound induces death in human liver cancer cells: possible pharmacological properties:”

Continue reading Two journals retracting papers from University of Malaya featuring widely criticized figures

Highly cited cancer researcher logs 8th, 9th retractions

Bharat Aggarwal
Bharat Aggarwal

Bharat Aggarwal, a highly cited cancer researcher who retired last year from MD Anderson, has logged two retractions following an investigation into his work, bringing his total to nine.

Aggarwal has threatened to sue us in the past, and told us that MD Anderson has been investigating his work. Earlier this year, Biochemical Pharmacology retracted seven studies of which he is the only common author, noting the “data integrity has become questionable.” Now, he’s earned two more retractions in Molecular Pharmacology, both for “inappropriate” or “unacceptable” image manipulation.

Both of the notices are paywalled (tsk, tsk). Here’s one for “Flavopiridol suppresses tumor necrosis factor-induced activation of activator protein-1, c-Jun N-terminal kinase, p38 mitogen-activated protein kinase (MAPK), p44/p42 MAPK, and Akt, inhibits expression of antiapoptotic gene products, and enhances apoptosis through cytochrome c release and caspase activation in human myeloid cells:” Continue reading Highly cited cancer researcher logs 8th, 9th retractions

Seventh retraction appears for cancer researcher who sued PubPeer commenters

sarkar
Fazlul Sarkar

Fazlul Sarkar, who sued PubPeer commenters for criticizing his work, has logged two more retractions, bringing his total to seven.

The two retractions appear in the Journal of Cellular Physiology, and follow five others released last week by another Wiley journal, Journal of Cellular Biochemistry. All notices mention an investigation at Wayne State University, where Sarkar is on the faculty.

Here’s the notice for “Activated K-Ras and INK4a/Arf Deficiency Promote Aggressiveness of Pancreatic Cancer by Induction of EMT Consistent With Cancer Stem Cell Phenotype:” Continue reading Seventh retraction appears for cancer researcher who sued PubPeer commenters

Researcher suing PubPeer commenters earns 5 retractions following investigation

sarkar
Fazlul Sarkar

An investigation at Wayne State University has prompted five retractions for a scientist who is suing PubPeer commenters after they criticized his work on the site.

The investigation into Fazlul Sarkar and his co-authors found that the papers contain images that were “inappropriately manipulated” or “inappropriately re-used and re-labeled.” All five retraction notices are from the Journal of Cellular Biochemistry.

Here’s the retraction notice for “Concurrent inhibition of NF-κB, cyclooxygenase-2, and epidermal growth factor receptor leads to greater anti-tumor activity in pancreatic cancer:

Continue reading Researcher suing PubPeer commenters earns 5 retractions following investigation