Category: lack of IRB approval

Cardiac arrestees: Questions surface about Heart paper from Italian group that faces charges

heartcoverWe don’t usually cover “pretractions” (see #5 for why), but our friend Larry Husten over at Forbes has a story today about what appears to be a dead paper walking.

The article, in Heart, comes from a group of prominent researchers in Italy who have been arrested for possibly failing to adequately consent their patients, among other potential misdeeds.

According to Husten, the 2010 article in question, “A randomised trial of target-vessel versus multi-vessel revascularisation in ST-elevation myocardial infarction: major adverse cardiac events during long-term follow-up,” by Maria Grazia Modena (a past president of the Italian Society of Cardiology) and colleagues, may have been grossly misrepresented to the journal. Continue reading Cardiac arrestees: Questions surface about Heart paper from Italian group that faces charges

ORI, OHRP find “some human subject issues” in Henschke lung cancer studies, but no evidence of misconduct

cancerWe have an update on two papers about lung cancer screening by Claudia Henschke and colleagues that were subject to an Expression of Concern early last year.

The original Expression of Concern in Cancer read, in part: Continue reading ORI, OHRP find “some human subject issues” in Henschke lung cancer studies, but no evidence of misconduct

New Mexico obstetrics researcher violated research subject protocols: Retraction notice

gynoncLaurence Cole, an obstetrics researcher at the University of New Mexico, made an appearance on this blog in November 2011 after the American Journal of Obstetrics & Gynecology published a remarkably heavy-handed retraction of one of his papers.

Shortly after, we learned that the retraction was preceded by a strongly-worded letter from an attorney representing a company that had been miffed by the content of Cole’s article (the issue involved the effectiveness of commercially-available pregnancy tests, and Cole’s failure to adequately disclose a past relationship with the aggrieved company’s competitor). That letter read, in part: Continue reading New Mexico obstetrics researcher violated research subject protocols: Retraction notice

IRB issues force retraction of ulcer bug bacteria paper

jpgnA group of Turkish researchers has had a paper retracted on how to treat the bacterium that cause ulcers after the journal’s editors found “issues related to the institutional review board approval” of the project.

Here’s the retraction notice from the Journal of Pediatric Gastroenterology and Nutrition: Continue reading IRB issues force retraction of ulcer bug bacteria paper

Social sciences paper retracted for lack of ethical approval

social science and medicineA University of Minnesota social scientist who studies health disparities has retracted a study that apparently lacked ethical approval.

Here’s the notice for “Deservingness to state health services for South – South migrants: A preliminary study of Costa Rican providers’ views,” a paper in Social Science & Medicine by Kate Goldade and a colleague: Continue reading Social sciences paper retracted for lack of ethical approval

Retraction record broken, again: University report should up Fujii total to 183

a&amisconductcoverKeeping up with the various investigations into the activities of Yoshitaka Fujii — the assumed record holder for retractions by a single author, with 172 likely — can be a challenge. Between the journals pulling his papers and the institutions looking into his misconduct, it’s hard to keep everything straight.

But we have a new report, from a past employer, that makes for interesting reading and helps tie up some loose ends. The document is from Tsukuba University, where Fujii worked more than a decade ago when questions about the propriety of his findings first surfaced. Continue reading Retraction record broken, again: University report should up Fujii total to 183

Two Moriguchi stem cell papers being retracted

It was, as Nature News wrote last month, a story that “seemed too good to be true:”

Stem-cell transplant claims debunked

Transplant of induced pluripotent stem cells to treat heart failure probably never happened

Hisashi Moriguchi, a visiting researcher at the University of Tokyo, had claimed a result that would have put him years ahead of researchers toiling in stem cell research. But the claims were met with a great deal of doubt — to say the least — and the story began to unravel when Harvard, where Moriguchi said he’d done the work, denied it had ever taken place.

And as expected, the retractions have now started. Today, a Nature Publishing Group journal said they would be retracting two papers, “A therapeutic method for the direct reprogramming of human liver cancer cells with only chemicals” and “Successful cryopreservation of human ovarian cortex tissues using supercooling.” The notices for the Scientific Reports papers will both say the same thing: Continue reading Two Moriguchi stem cell papers being retracted

PLoS ONE retracts paper on treatment of tissue disease for lack of ethical approval, erroneous data

PLOS ONE has retracted an article it published earlier this year by a group from Australia who failed to receive adequate ethics approval for their study.

The paper, “Late Complications of Clinical Clostridium Histolyticum Collagenase Use in Dupuytren’s Disease,” came from Warren M. Rozen, Yasith Edirisinghe and John Crock (sorry, irony machine not working today). Dupuytren’s causes thickening of the fascia in the hands and often requires surgery.  In 2011 the FDA approved a treatment for the ailment that involves injections of an enzyme — Clostridium Histolyticum Collagenase, or CHC — into the affected area.

The Aussie article looked at the effects of CHC injections in 12 patients over one year, finding that two of the patients suffered Continue reading PLoS ONE retracts paper on treatment of tissue disease for lack of ethical approval, erroneous data

Another odd retraction for alcohol researcher, this time for lack of animal research committee approval

The journal Neuroscience has retracted a 2011 paper by an alcohol researcher from the United Arab Emirates, who apparently conducted some mouse studies without the blessing of his institution’s animal ethics officials. At least, that’s what the retraction notice would have us believe.

The paper in question, “The pre-synaptic metabotropic glutamate receptor 7 “mGluR7” is a critical modulator of ethanol sensitivity in mice,” by Amine Bahi, was published in December 2011 and cited three times (twice by the author), according to Thomson Scientific’s Web of Knowledge. But as the notice explains:

Continue reading Another odd retraction for alcohol researcher, this time for lack of animal research committee approval

Another retraction from chiropractic researchers for lack of ethics approval

Chiropractic & Manual Therapies — formerly known as Chiropractic & Osteopathy — has retracted a 2010 paper by a team of Australian researchers who failed to obtain institutional review board (IRB) approval for their studies.

As the notice for “A descriptive study of a manual therapy intervention within a randomised controlled trial for hamstring and lower limb injury prevention” explains: Continue reading Another retraction from chiropractic researchers for lack of ethics approval