Retraction count for resveratrol researcher Dipak Das rises to 12

Das, via UConn

Dipak Das, the UConn researcher whom the university earlier ths year found to have fabricated or falsified data more than 100 times, has four more retractions to his name.

The notices appear in the June 1, 2012 issue of the American Journal of Physiology: Heart and Circulatory Physiology, and suggest that Das was not all that cooperative: Continue reading Retraction count for resveratrol researcher Dipak Das rises to 12

Why retraction notices matter: Group’s repeated misuse of figures gets different play from five journals

For some journals, thorough retraction notices are the rule — and, when misconduct is involved, the price authors pay for abusing the trust of the editors and the readers. Others seem to take a more casual approach. Guess which we think is best.

Consider the case of a group of researchers in China led by Tan Jinquan, an immune system expert at Wuhan University. Over the past two years or so, Jinquan and colleagues have lost no fewer than a half-dozen papers containing evidence of image manipulation. But, depending on the journal pulling the articles, you might not know it.

Continue reading Why retraction notices matter: Group’s repeated misuse of figures gets different play from five journals

Authors retract two Cell Metabolism papers after “data were inappropriately removed from the laboratory”

A group of researchers at the University of Utah has retracted two papers from Cell Metabolism after they realized that a dismissed employee had tossed out data that were the basis of some error-laden figures.

Here’s the notice for both papers: Continue reading Authors retract two Cell Metabolism papers after “data were inappropriately removed from the laboratory”

Leading cancer vaccines researcher retracts paper for figure “discrepancies” flagged by watchdog blog

Gerold Schuler, a German immunology researcher who shared the 2006 Deutscher Krebspreis — aka the German Cancer Prize — for his work that contributed to cancer vaccines has retracted a paper in International Immunology following concerns raised by a German science watchdog blog.

Here’s the notice: Continue reading Leading cancer vaccines researcher retracts paper for figure “discrepancies” flagged by watchdog blog

Whistleblower forces retractions of four stem cell papers amid questions about more than a dozen studies

In a case that is a good reminder of why journal editors shouldn’t ignore anonymous tips, a Seoul National University stem cell researcher has been forced to retract four papers, and withdraw another under peer review, in Antioxidants & Redox Signaling following a whistleblower’s exhaustive analysis.

Two retractions by Soo Kyung Kang, a professor of veterinary biotechnology at Seoul National University, appeared on May 9 after an anonymous whistleblower sent a 70-slide PowerPoint presentation to the editors of ten journals that contained evidence of suspicious floating error bars, errors larger than actual measurements, pasted-together lanes in PCR gels and RNA and CHIP blots and several cases where the same control blot data is shown across different experiments and in different papers. In all, the whistleblower raises questions about 14 papers in the ten journals.

Here is the May 9 notice for “Nuclear Ago2/HSP60 contributes to broad spectrum of hATSCs function via Oct4 regulation”: Continue reading Whistleblower forces retractions of four stem cell papers amid questions about more than a dozen studies

Retraction seven for Shouwei Han, this one in the American Journal of Physiology

ShouWei Han, who has been forced to retract six papers from various physiology journals following an investigation into his work by his former employer, the University of Louisville, has added another one to his tally.

Here’s the notice, from the American Journal of Physiology: Lung Cellular and Molecular Physiology: Continue reading Retraction seven for Shouwei Han, this one in the American Journal of Physiology

Group investigated by University of Louisville corrects lung cancer paper after retracting six others

A group of researchers whose work has been under investigation at the University of Louisville has issued a correction for a paper in the American Journal of Respiratory Cell and Molecular Biology (AJRCMB).

The correction follows three retractions each in the Journal of Biological Chemistry and the AJRCMB, the latter of which made it clear that lab member ShouWei Han was responsible for the manipulations and duplications that brought down the papers. Here’s the new notice, which appeared in the March 1, 2012 issue of the journal: Continue reading Group investigated by University of Louisville corrects lung cancer paper after retracting six others

JCO expresses concern over images from Spanish group that had aroused earlier concern

The Journal of Clinical Oncology has issued an expression of concern about a 2003 article by a group of researchers in Spain who appear to have had recurrent problems with images.

The paper has been cited 56 times, according to Thomson Scientific’s Web of Knowledge. Here’s the notice:

It has been brought to our attention, regarding Figure 1, Part A, that similarity exists between bands 3, 4, and 5 of the top row and bands 1, 2, and 3 of the bottom row, including the presence of artifacts, in the April 15, 2003 article by [Jose] RomanGomez et al, entitled, “Cadherin-13, a Mediator of Calcium Dependent Cell-Cell Adhesion, Is Silenced by Methylation in Chronic Myeloid Leukemia and Correlates With Pretreatment Risk Profile and Cytogenetic Response to Interferon Alfa” (J Clin Oncol 21:1472-1479, 2003).  This similarity has raised concerns about whether these rows represent independent data. We alerted the corresponding author, Dr. Roman-Gomez, of this concern, and he has repeated the experiment shown in the original Figure 1, with the results below. Although the results of the figure appear to be unchanged, we wish to inform the readers of this issue, so that they may make their own independent assessment.

Continue reading JCO expresses concern over images from Spanish group that had aroused earlier concern

Can we trust Western blots?

The title of this post is the headline of our latest column for LabTimes. It’s inspired by a number of animated discussions on Retraction Watch following our coverage of various Western blot problems — some unintentional, and some, well, less so.

Take, for example, this comment, which we quote in the column: Continue reading Can we trust Western blots?

Three more retractions for resveratrol researcher Dipak Das, in free radical journals

Das, via UConn

The retraction count for Dipak Das, the resveratrol researcher whom the University of Connecticut found to have committed 145 counts of fabrication and falsification of data, has risen to eight with withdrawals by Free Radical Biology & Medicine and Free Radical Research.

The two Free Radical Biology & Medicine retractions, for “Expression of the longevity proteins by both red and white wines and their cardioprotective components, resveratrol, tyrosol, and hydroxytyrosol” (cited 38 times, according to Thomson Scientific’s Web of Knowledge) and “Redox regulation of resveratrol-mediated switching of death signal into survival signal” (cited 32 times), are carefully detailed and read the same way: Continue reading Three more retractions for resveratrol researcher Dipak Das, in free radical journals