Journal retracts paper due to image mismatch; one co-author alleges fraud

Researchers have retracted a biology paper that included an image mismatch — despite the fact that, as they claim, another image in the same paper confirms the original findings.

The authors say they plan to resubmit the paper with the corrected figure panel.

The second to last author — Carlo Croce, chair of the department of cancer biology and genetics at The Ohio State University — told us he believes there’s more to the retraction than what the notice says. Specifically, he said that the paper includes an image from a previous paper by the same authors, which he called “fraud.”

Here’s the latest retraction notice, published in Cell Death and Differentiation:

Continue reading Journal retracts paper due to image mismatch; one co-author alleges fraud

Surgery chair who blamed image issues on software logs three more retractions

A researcher who claimed image problems in a retracted paper were the result of a software glitch, and not intentional, has lost three more papers — all for image manipulation.

In two notices, the Journal of Biological Chemistry specifies that duplicated images were used to represent different experimental conditions; one notice simply says the paper was affected by image manipulation.

All of the notices specify the papers are being retracted by the publisher, the American Society for Biochemistry and Molecular Biology — which this month published a set of recommendations for preparing a paper, including how to avoid excessive manipulation.

The papers were published between 2002 and 2010, and all share the same last author (Paul Kuo, currently chair of surgery at Loyola Medicine) and first author (Hongtao Guo, at Duke).

Here’s the first notice:

Continue reading Surgery chair who blamed image issues on software logs three more retractions

Prominent Harvard researcher issues second retraction, again citing duplication

The former president of the Joslin Diabetes Center has withdrawn a second article within a month of his first, and issued extensive corrections to another paper in the same journal, all due to figure errors.

In November, we reported that Carl Ronald Kahn — also affiliated with Harvard Medical School — had pulled a highly cited 2005 paper from The Journal of Clinical Investigation because of image duplication issues, which Kahn told us were introduced during figure assembly. This December, Kahn retracted a 2003 paper published in The Journal of Biological Chemistry (JBC)—again due to duplication issues that the authors believe “were inadvertently introduced during figure assembly.”

Here’s the retraction notice for “Bi-directional regulation of brown fat adipogenesis by the insulin receptor,” cited 46 times, according to Clarivate Analytics’ Web of Science, formerly part of Thomson Reuters:

Continue reading Prominent Harvard researcher issues second retraction, again citing duplication

Breast cancer studies by fired Pfizer employee retracted

Last year, Pfizer fired one of its scientists following an investigation that ended with requests for retraction of five of her studies. Now, two of the five papers, which were first flagged on PubPeer, have been retracted.

One notice cites the Pfizer investigation, which found that cancer researcher Min-Jean Yin had included duplicated images in all five papers. Yin is the last author on both retracted papers.

Here’s the first notice from Clinical Cancer Research, which says most or all of the questioned images appear to be duplicates, and Pfizer — who sponsored the study and requested the retraction — can’t find the originals:
Continue reading Breast cancer studies by fired Pfizer employee retracted

Journal retracts gastric cancer study with multiple duplications, authors MIA

An oncology journal has decided to retract a 2012 paper on gastric cancer after discovering duplicated data in multiple figures.

According to the retraction notice, the journal’s editorial board received a tip from a reader regarding the potential figure issues. Oncology Reports launched an investigation, which confirmed the allegations. The authors failed to respond to the journal’s multiple requests for more information.

Here’s the retraction notice: Continue reading Journal retracts gastric cancer study with multiple duplications, authors MIA

“An example for all authors to uphold:” Researcher logs 5 corrections

A scientist in Ireland has corrected five of his papers in a single journal dating back more than a decade, after image-related problems were brought to his attention.

Four of the newly corrected papers have a common last and corresponding author: Luke O’Neill of Trinity College Dublin in the Republic of Ireland. O’Neill is also a co-author of the remaining paper that was fixed. O’Neill told us the mistakes were a “bit sloppy,” noting that he takes responsibility for the errors in the four papers on which he is last author.

O’Neill forwarded Retraction Watch a comment he received from Kaoru Sakabe — data integrity manager at the American Society for Biochemistry and Molecular Biology (which publishes The Journal of Biological Chemistry (JBC)) — that reads:

Continue reading “An example for all authors to uphold:” Researcher logs 5 corrections

Japan group earns 4th retraction following investigation

Researchers in Japan have issued their fourth retraction, noting that the same figures were used to depict different experimental conditions.

The group lost two papers in 2015 for the same reason, following a misconduct investigation at Oita University in Japan. Last year, the same group notched another retraction, and pegged the responsibility for the problematic figures on first author Satoshi Hagiwara.

Now, the group has published a fourth retraction in the European Journal of Pharmacologythe latest notice doesn’t identify a culprit. All four retracted papers list Hagiwara as first author.

Here’s the latest retraction notice: Continue reading Japan group earns 4th retraction following investigation

Authors use same images in two studies — one is retracted, the other flagged by journal

After researchers in China included the same images in two papers published online one month apart, one paper has been retracted, and the other flagged with an expression of concern. 

According to the retraction notice in the International Journal of Molecular Medicine (IJMM), the authors intended that the two different papers offered “different research perspectives.”

Meanwhile, the Chinese Medical Journal — which published the same images one month later — has issued an expression of concern (EOC), noting it “should not be considered as a statement regarding the validity of the work.” Both papers describe how cells regulate blood flow to the retina.

Normally, journals choose to retract the most recent paper containing duplicated images, but in this case, the IJMM paper was published online in February 2016, and the Chinese Medical Journal in March.

Here’s the retraction notice: Continue reading Authors use same images in two studies — one is retracted, the other flagged by journal

Prominent researcher in Taiwan loses another paper for image duplication

In November, a vice president at an institution in Taiwan retracted a hotly debated cancer paper from Nature Cell Biology, citing image problems including duplications. Now, the Journal of Biological Chemistry has done the same, again citing image duplications.

There are a few things to note about the latest retraction: One, the last author is again Kuo Min-liang — who holds an appointment at National Taiwan University (NTU), and is also a vice president at Kaohsiung Medical University in Taiwan. Kuo is currently facing allegations that he accepted bribes to add co-authors to his papers; NTU told us it is investigating the latest retraction in the Journal of Biological Chemistry, including Kuo.

The other notable feature of the retraction is the notice itself, which lists a remarkable number of duplicated images. Take a look:

Continue reading Prominent researcher in Taiwan loses another paper for image duplication

Researcher loses 4th paper flagged by misconduct probe

A researcher in Germany has logged her fourth retraction following an investigation by her former employer that found evidence of scientific misconduct.

The latest retraction for Tina Wenz in the Journal of Applied Physiology mentions the probe at the University of Cologne in Germany, which recommended retracting six of her papers. One had already been retracted by the time the report was released; last month, we reported that two others had been pulled. Now, we’ve come across a fourth.

Here’s the latest retraction notice: Continue reading Researcher loses 4th paper flagged by misconduct probe