A potential weight loss drug has been dealt what could be a serious setback after regulators found problems at two trial sites.
While awaiting a final report, The Lancet, which published a study of the drug, tesofensine, has issued an Expression of Concern: Continue reading Trial irregularities earn Lancet study of potential weight loss drug tesofensine Expression of Concern
PLOS ONE has issued a fascinating expression of concern about data collection in a paper it published late last year on the possible spread of deadly viruses among Indonesian orangutans. The case has been brought to the attention of the Indonesian government, but more on that in a moment.
The article, published last July by an international group of primate scientists led by Chairul Nidom, a virologist at Indonesia’s Airlangga University, sounded an alarm about “wild” orangutans in Borneo: Blood tests of 353 “healthy” animals showed antibodies for viruses akin to Ebola. What’s more, the filoviruses viruses to which the antibodies responded, as New Scientist and other outlets reported when the original paper came out, included strains not previously seen outside Africa (as well as Marburg, another deadly infection).
The article immediately prompted two comments. The first, by a poster called orangutanborneo, raised questions about the scale and logistics of the project: Continue reading Orangutan-Ebola link in PLOS ONE paper under scrutiny
A six year-old review on bird flu that failed to credit some content from another six year-old review of bird flu is now stamped with an Expression of Concern.
Here’s the notice, from Influenza and Other Respiratory Viruses: Continue reading Flu paper duplication earns Expression of Concern
The Journal of the American College of Cardiology, or JACC, has issued expressions of concern for three papers by Don Poldermans, the Dutch cardiologist who was fired earlier this year amid allegations of misconduct.
Cardiobrief’s Larry Husten had the story first.
The, um, heart of the matter is that neither the investigators at Erasmus Medical Center, Poldermans’ former institution, nor the JACC editors, can say whether the researchers conduct rose to the level of fabricating data. As the Notice of Concern states: Continue reading Concern — in triplicate — arrives for Poldermans papers
Diederik Stapel has three more retractions, making 31.
The most recent three we’ve found all appear in the European Journal of Social Psychology: Continue reading Diederik Stapel notches retractions 29, 30, and 31
PLoS ONE has issued two Expressions of Concern on unrelated studies, each of which offers plenty to be concerned about — and not just about the research itself.
One is a casualty of our old friend, Jesús Lemus, the Spanish veterinary scientist accused of fabricating his data.
The article, titled “The PHA-Skin Test Reflects Acquired T-Cell Mediated Immunocompetence in Birds,” was published in September 2008 and cited 61 times, according to Google Scholar.
Back in April, the publisher posted this comment to the paper: Continue reading A pair of expressions of concern in PLOS ONE over vet science papers
A difficult authorship dispute, involving two journals and at least two continents, has led to an Expression of Concern in the Brazilian Journal of Rheumatology.
Here’s the Expression of Concern: Continue reading Bitter authorship issues prompt Expression of Concern in rheumatology journal
The editors of the World Journal of Emergency Surgery have published an Expression of Concern about a paper after they couldn’t verify one of the three case reports in it.
Here’s the notice for “Necrotizing fasciitis: literature review of contemporary strategies for diagnosing and management with three case reports: torso, abdominal wall, upper and lower limbs,” by surgeons from Split and Zagreb, Croatia: Continue reading Surgery journal issues Expression of Concern when institution can’t confirm case study details “for legal reasons”
JAMA has issued its first-ever Expression of Concern over a 2007 study of hip protectors in the elderly that came under scrutiny from Federal regulators.
As the Boston Globe was first to report yesterday, the journal’s editor and executive deputy editor wrote in a notice published online: Continue reading JAMA’s first-ever Expression of Concern appears for hip protector study
The British Journal of Clinical Pharmacology has issued an “expression of concern” for a 2003 review article, based on a previous lecture, with close echoes to a paper that had appeared in one of The Lancet titles.
Here’s the notice for the article, by Peter Winstanley, dean of the Warwick Medical School in the United Kingdom: Continue reading Pharmacology journal expresses concern over “similar, but updated” review