Karel Bezouška, the Czech biochemist who was caught on hidden camera breaking into a lab fridge to fake results, has turned it up to eleven with two new retractions.
Both retractions appeared in Biochemical and Biophysical Research Communications, one in October 2014 and one in January 2015. His story began two decades ago in 1994, when he published a paper in Nature that couldn’t be reproduced, and was eventually retracted in 2013.
How should scientists think about papers that have undergone what appears to be a cursory peer review? Perhaps the papers were reviewed in a day — or less — or simply green-lighted by an editor, without an outside look. That’s a question Dorothy Bishop, an Oxford University autism researcher, asked herself when she noticed some troubling trends in four autism journals.
Recently, Bishop sparked a firestorm when she wrote several blog posts arguing that these four autism journals had a serious problem. For instance, she found that Johnny Matson, then-editor of Research in Developmental Disabilities and Research in Autism Spectrum Disorders, had an unusually high rate of citing his own research – 55% of his citations are to his own papers, according to Bishop. Matson also published a lot in his own journals – 10% of the papers published in Research in Autism Spectrum Disorders since Matson took over in 2007 have been his. Matson’s prodigious self-citation in Research in Autism Spectrum Disorders was initially pointed out by autism researcher Michelle Dawson, as noted in Bishop’s original post.
Short peer reviews of a day or less were also common. Matson no longer edits the journals, both published by Elsevier.
Bishop noted similar findings at Developmental Neurorehabilitation and Journal of Developmental and Physical Disabilities, where the editors (and Matson) frequently published in each others’ journals, and they often had short peer reviews: The median time for Matson’s papers in Developmental Neurorehabilitation between 2010 and 2014 was a day, and many were accepted the day they were submitted, says Bishop.
Although this behavior may seem suspect, it wasn’t necessarily against the journals’ editorial policies. This is the peer review policy at RIDD:
Teresita Briones, a former nursing professor at Wayne State University in Detroit who studied neuroscience, manipulated images in five papers, according to the Office of Research Integrity.
Robert Weinberg, a prominent cancer scientist whose papers often notch hundreds or thousands of citations, has lost a fourth paper, this time a 2009 publication in Cell.
Journal Genes and Development pulled two of Weinberg’s papers in March, stating that they had retracted the 2009 study because data from several experiments was used in figures that seemed to represent only one. The Genes and Development papers were sunk because the “same analytical methodology was used.”
At the time, the Cell retraction was unavailable, though a spokesperson informed us it was forthcoming. The paper has been cited 482 times, according to Thomson Scientific’s Web of Knowledge.
A paper whose expression of concern we covered in November 2014 has been retracted and republished “because of the extent of the changes necessary,” according to the Lancet Respiratory Medicine.
This study was a meta-analysis of research on how the timing of tracheostomies — placing a breathing tube directly into the windpipe — affects patients’ mortality rate. The original paper found that critically ill patients who received a tracheostomy earlier fared better than those for whom the procedure was delayed for weeks after intubation, the recommended practice.
However, when the authors calculated how many patients died, they assumed that any patient who wasn’t discharged from the intensive care unit (ICU) had died there, instead of looking for other explanations. This made their estimates unreliable.
The publisher convened a panel, which ultimately decided retraction and republication was the most appropriate course of action.
A 2014 Cancer Cell paper became the subject of an erratum in January 2015, shortly after PubPeer members began criticizing the data. However, many issues brought up by commenters weren’t addressed in the correction notice, including a figure that might be two experiments spliced together to look like one.
The paper, led by Guido Franzoso at Imperial College London, claims that a new cancer drug called DTP3 kills myeloma cells “without causing any toxic side effects,” according to a press release from the school. Guido Franzoso is the founder of Kesios Therapeutics, a drug company which is set to begin clinical trials on DTP3.
The correction indicates that Western blots were cropped badly, which omitted several panels discussed in the text, while an “extra time point” was included accidentally. An antibody was also omitted from the description of the procedure.
PubPeer commenters have noticed additional issues, such as a criticism of figure 3D, which were not included or changed in this correction.
Prominent plant researcher Mark Estelle has retracted a paper on plant hormones after follow-up studies showed the conclusions were incorrect.
The hormone in question, auxin, is a major player in plant growth and development. The retracted Current Biology paper reported that a certain auxin receptor, designated AFB4, downregulates the responses of cabbage-cousin Arabidopsis thaliana to the signaling molecule. But after publication, the researchers experimented with a mutant seedling that didn’t produce the receptor, and discovered it didn’t overreact to auxin signals, indicating the receptor wasn’t playing a major role in limiting the effects.
Estelle, a Howard Hughes Medical Institute investigator based at the University of California, San Diego, told us he and his team are working on a paper that will contain the accurate data from the paper, along with new findings.
The journal Food Microbiology has pulled a 2012 paper on pork processing which, as we reported earlier, contained salami-sliced data.
The article, “Bayesian inference for quantifying Listeria monocytogenes prevalence and concentration in minced pork meat from presence/absence microbiological testing,” came from a group at the Department of Food Science and Technology at the Agricultural University of Athens, in Greece.
A group of geologists in China have lost their paper on the aerodynamics of sand particles because the article was mashed together from previous publications.
The article, “The influence of sand diameter and wind velocity on sand particle lift-off and incident angles in the windblown sand flux,” appeared in the May 2013 issue of Sedimentary Geology. It was written by a team from the Key Laboratory of Mechanics on Western Disaster and Environment at Lanzhou University.
Karel Bezouška, the Czech biochemist who was caught on hidden camera breaking into a lab fridge to fake results, has turned it up to eleven with two new retractions.
