Former medical school dean earns sixth retraction

Joseph Shapiro

A kidney researcher and former dean of a medical school has now had six papers retracted and one marked with an expression of concern in a little more than a year

The latest retraction for Joseph I. Shapiro, of a 2015 paper in Science Advances, comes two years after PubPeer commenters began posting about potentially duplicated images in the article, and one year after the authors corrected two of its figures. 

Shapiro, the corresponding author on the article, stepped down as dean of the Joan C. Edwards School of Medicine at Marshall University in Huntington, W. Va., on June 30th of this year, but remains a tenured professor at the institution. Neither he nor  Komal Sodhi, the first author on the article and also of Marshall, have responded to our request for comment. 

Retractions of work Shapiro led began last September, according to our database, following critical comments on PubPeer. 

Continue reading Former medical school dean earns sixth retraction

‘My egregious delay’: Science journal takes more than three years to retract paper after university investigation

The editor of a Science family journal waited three years before beginning the process of retracting a paper after learning that the University of Wisconsin at Madison had found duplication and mislabeling but no misconduct, Retraction Watch has learned.

As we reported last November, the paper, “The receptor tyrosine kinase AXL mediates nuclear translocation of the epidermal growth factor receptor,” was published in 2017 in Science Signaling. It was retracted this past November, and the notice referred to a university investigation.

That prompted us to submit a public records request on November 12 for the investigation as well as any correspondence between the university and the journal. In a response on January 12, the university denied our request for the report of the investigation, saying that “There is a review still underway at the federal level regarding this issue.” (That is a good reminder of how long the U.S. Office of Research Integrity can take to review such investigations.)

But the university released correspondence between Deric Wheeler, the corresponding author of the paper, and John Foley, the editor of the journal, which we’ve made available here. The thread begins on July 6, 2021 – just one month shy of three years after Foley learned of an investigation into the research – with an email from Foley in which the editor acknowledged “an egregious delay”:

Continue reading ‘My egregious delay’: Science journal takes more than three years to retract paper after university investigation

Why one biologist says it’s not too late to retract the “arsenic life” paper

David Sanders

An anniversary has prompted this reconsideration of the revolution in biochemistry that wasn’t: the “arsenic bacteria.” Just over 10 years have passed since an infamous Dec. 2, 2010, NASA press conference, which promised the revelation of “an astrobiology finding that will impact the search for evidence of extraterrestrial life.” 

Of course, nothing of the kind occurred. The carefully curated moment was less informative for its scientific value — in effect, nil — than for what it says about how years of attention-seeking and speculation in biology can drive an agenda. Equally concerning, despite the intervening decade in which other researchers debunked the overhyped result, is that the journal involved has yet to retract the article in question, allowing it to live in a zombie state.   

The announcement at the press conference was, to the disappointment of many, the supposed “discovery” of a microbe that could grow on arsenate in the absence of phosphate and incorporate arsenic instead of phosphorus in macromolecules such as nucleic acids and proteins that was being published in ScienceSteven Benner (referring to himself as a curmudgeon) was the only individual at the press conference who talked real sense by undermining the claims.   Mary Voytek, NASA Senior Scientist for Astrobiology (a position she still occupies) employed a Star Trek analogy:

Continue reading Why one biologist says it’s not too late to retract the “arsenic life” paper

Authors retract highly cited 2014 Science paper

The authors of a 2014 paper in Science have retracted it, after becoming aware that impurities in the chemicals they used for their experiments may have generated the apparent findings.

The paper, “Ammonia synthesis by N2 and steam electrolysis in molten hydroxide suspensions of nanoscale Fe2O3,” has been cited 323 times, according to Clarivate Analytics’ Web of Science, earning it a “hot paper” designation. According to a summary of the work, “the protocol points to a way to produce ammonia from purely renewable resources.”

Here’s the retraction notice:

Continue reading Authors retract highly cited 2014 Science paper

Too hot to handle: Authors retract Science paper on electromagnetics

Sometimes scientific findings can be too hot to handle. Literally. 

A team of researchers in India and Japan who reported breakthrough results in two papers about electromagnetics, including an article in Science, are retracting the articles because the exciting data resulted from experimental error. To be precise: unbeknownst to them, inadvertent heating of their samples had contaminated their data. 

The first author of both articles is Chanchal Sow, of the Indian Institute of Technology in Kanpur. The last author on both is Yoshiteru Maeno, a professor of physics at Kyoto University. 

Here’s the notice:

Continue reading Too hot to handle: Authors retract Science paper on electromagnetics

Former UCSD prof who resigned amid investigation into China ties has paper flagged for using the wrong test

Kang Zhang

Science Translational Medicine has issued an expression of concern about a 2020 paper on the genetics of colorectal cancer by a group in China whose results were pegged on a test that couldn’t have produced the findings. 

The article, “Circulating tumor DNA methylation profiles enable early diagnosis, prognosis prediction, and screening for colorectal cancer,” appeared in January, with authors from both academia and an outfit called the Guangzhou Youze Biological Pharmaceutical Technology Company. 

Continue reading Former UCSD prof who resigned amid investigation into China ties has paper flagged for using the wrong test

Indiana University paper about lung transplantation retracted after misconduct finding

After a finding of data manipulation, the corresponding author of a 2014 paper by a team of researchers at Indiana University has retracted the work.

Here’s the notice in Science Translational Medicine: Continue reading Indiana University paper about lung transplantation retracted after misconduct finding

Science retracts paper after Nobel laureate’s lab can’t replicate results

Science is retracting a 2014 paper from the lab of a Nobel winner after replication attempts failed to conclusively support the original results.

In January, Bruce Beutler, an immunologist at University of Texas Southwestern Medical Center and winner of the 2011 Nobel Prize in Physiology or Medicine, emailed Science editor-in-chief Jeremy Berg to report that attempts to replicate the findings in “MAVS, cGAS, and endogenous retroviruses in T-independent B cell responses” had weakened his confidence in original results. The paper had found that virus-like elements in the human genome play an important role in the immune system’s response to pathogens.

Although Beutler and several co-authors requested retraction right off the bat, the journal discovered that two co-authors disagreed, which Berg told us drew out the retraction process. In an attempt to resolve the situation, the journal waited for Beutler’s lab to perform another replication attempt. Those findings were inconclusive and the dissenting authors continued to push back against retraction.

Berg told us:

Continue reading Science retracts paper after Nobel laureate’s lab can’t replicate results

Science journal flags cancer paper under investigation for image manipulation

Science Signaling has issued an expression of concern for a 2016 paper, citing an institutional investigation into image manipulation.

According to a spokesperson for the journal, the corresponding author, Tanya Kalin, became concerned that two images in the paper had been manipulated. Kalin then notified the research integrity officer at Cincinnati Children’s Hospital Medical Center, where she is based.

On May 9 2017, Kalin alerted the journal to the investigation. A week later, the hospital’s research integrity officer followed up with the journal, flagging the figures under question.  The journal then prepared an expression of concern (EOC) to alert readers to the issues and the institution’s investigation.  

Here’s the EOC notice for “The transcription factor FOXF1 promotes prostate cancer by stimulating the mitogen-activated protein kinase ERK5:” Continue reading Science journal flags cancer paper under investigation for image manipulation

“Data had been manipulated:” Science Translational Medicine retracts paper

Science Translational Medicine has retracted a paper by researchers based in Switzerland, after an investigation concluded two figures had been manipulated.

The investigation occurred at the University of Basel. It’s not clear what prompted it, but the paper has been discussed at length on PubPeer. After the investigation concluded two figure panels included manipulated data, the last author asked to retract the paper.

Here’s the notice:

Continue reading “Data had been manipulated:” Science Translational Medicine retracts paper