Authors retract meningitis paper over permission — but data are in a public database

plos1A study characterizing subtypes of the bacteria that cause bacterial meningitis is being retracted after the authors didn’t have permission to publish the data, even though the data itself remain available in a public database.

The paper, in PLOS ONE, relied on a laboratory collection of patient samples. In October, the authors retracted it because they “did not have permission” from the laboratory “to publish the data in their current form.” The data — anonymized — are now available at PubMLST.

Here’s the retraction notice, published on October 16: Continue reading Authors retract meningitis paper over permission — but data are in a public database

Breakfast study mischaracterized funding by cereal group

Screen Shot 2015-12-07 at 5.42.55 PM

PLOS ONE has quickly corrected an October analysis of what children in Malaysia eat for breakfast, after the study neglected to note it benefited from mistakenly noted an unrestricted research grant from cereal companies supported author salaries. The grant supported the salaries of research assistants, according to the correction note.

Per the authors’ request, the journal has noted that the study received financial support from Nestlé R&D Center in Singapore and Cereal Partners Worldwide, a collaboration between General Mills Inc. and Nestlé S.A., with the goal of selling cereal outside the US and Canada. These funders provided “salaries for research assistants” for the MyBreakfast study, on which the analysis is based, according to the note.

The paper includes authors affiliated with Nestlé and Cereal Partners Worldwide, as well as a detailed “Competing interests” section, which outlines the relationships with these companies.

The correction note explains the information that should have appeared in the funding section of the article:

Continue reading Breakfast study mischaracterized funding by cereal group

PLOS ONE issues editor’s note over controversial chronic fatigue syndrome research

Screen Shot 2015-12-15 at 11.42.08 PM

After a request for the original data was denied, PLOS ONE editors have flagged a 2012 sub analysis of a controversial clinical trial on chronic fatigue syndrome with an editor’s note.

The editor’s note — which reads like an Expression of Concern — reiterates the journal’s policy that authors make data and materials available upon request, and notes that staff are following up on “concerns” raised about the study.

There have been numerous requests for data from the “PACE” trial, as the clinical trial is known, which the authors say they have refused in order to protect patient confidentiality. On November 13, James Coyne, a psychologist at the University Medical Center, Groningen, submitted a request for the data from the PLOS ONE paper to King’s College London, where some of the authors were based. According to Coyne’s WordPress blog (he also has a blog hosted by PLOS), the journal asked him to let them know if he “had any difficulties obtaining the data.” He did — KCL denied the request last Friday (the whole letter is worth reading):

The university considers that there is a lack of value or serious purpose to your request. The university also considers that there is improper motive behind the request. The university considers that this request has caused and could further cause harassment and distress to staff.

Last author Peter White at Queen Mary University of London, UK, told us the journal had not asked them to release the data, but he would work with PLOS to address any questions:

We understand PLOS One are following up concerns expressed about the article, according to their internal processes. We will be happy to work with them to address any queries they might have regarding the research.

Here’s the editor’s note for “Adaptive Pacing, Cognitive Behaviour Therapy, Graded Exercise, and Specialist Medical Care for Chronic Fatigue Syndrome: A Cost-Effectiveness Analysis,” in full:

Continue reading PLOS ONE issues editor’s note over controversial chronic fatigue syndrome research

Having non-replicable data may not hurt your rep, says study

plosoneAlthough many scientists fear putting their data to the test of replication efforts, due to the embarrassment they’d feel if their findings couldn’t be repeated, a new study suggests those fears are unfounded.

The paper, published last week in PLOS ONE, found that scientists overestimate how much having non-replicable data will hurt their careers, and the community values those who are honest about what went wrong.

Specifically, as the authors note:

Continue reading Having non-replicable data may not hurt your rep, says study

Cropped, spliced image leads to a PLOS One correction

Screen Shot 2015-10-01 at 4.27.21 PMA PLOS One paper on morphine treatment for cancer cells has a couple issues with figures, prompting a massive correction — what we affectionately call a “mega-correction” — by the journal.

In one figure, there was “an undisclosed splice.” Another figure contained two panels that were “mistakenly from the same sample.”

The 2013 paper in question, “Chronic Morphine Treatment Attenuates Cell Growth of Human BT474 Breast Cancer Cells by Rearrangement of the ErbB Signalling Network,” has been cited four times, according to Thomson Scientific’s Web of Knowledge.

Here’s the correction:

Continue reading Cropped, spliced image leads to a PLOS One correction

Mol bio paper pulled by PLOS following investigation into figures

Screen Shot 2015-11-17 at 11.58.47 AMPLOS Biology has retracted a paper about the molecular details of β-catenin expression following an investigation by the first author’s institution in Italy.

The investigation, by the Istituto Nazionale per la Ricerca sul Cancro, found that there were multiple “figure anomalies.” According to the note:

An explanation of inadvertent error was given for some of the issues identified, while for two issues, a satisfactory explanation could not be provided.

First author Roberto Gherzi says none of his co-authors helped prepare the figures. The authors maintain that the conclusions are unaffected, but that assurance wasn’t enough for the journal. Here’s more from the lengthy retraction note, which provides some backstory on the “serious concerns” regarding the data:

Continue reading Mol bio paper pulled by PLOS following investigation into figures

Mystery: PLOS One seeks investigation after publishing two papers with “substantial overlap”

Screen Shot 2015-10-01 at 4.27.21 PMPLOS One has retracted one of two cancer papers with “substantial overlap” that were reviewed simultaneously by different editors.

This one’s a bit of a mystery — neither of the papers share an author, and no authors share institutions. Once the editors discovered the overlap, they contacted the authors. One group of authors provided the requested documentation for the experiments. The other did not — so the editors retracted that article, even though it was published months before the other one.

In the meantime, the editors have asked the authors’ institutions investigate how the articles — which contain entire identical sentences, and some extremely similar figures — were put together. According to a statement from the editors:

Continue reading Mystery: PLOS One seeks investigation after publishing two papers with “substantial overlap”

Investigation ends in 6th retraction for Voinnet

PLOS PathogensA sixth paper co-authored by plant researcher Olivier Voinnet has been retracted by PLOS Pathogens “following an investigation into concerns.”

The investigation found “several band duplications” in one figure provided by fifth author, Patrice Dunoyer, who took it from “the Master thesis of a former student working under his supervision, without the prior consultation or consent of this student,” according to the notice. There was also an incorrect “loading control” in another figure, attributed to first author Raphael Sansregret and last author Kamal Bouarab. 

Voinnet and Bouarab, the study’s corresponding authors, took full responsibility for “the publication of this erroneous paper.”

Although investigators found that the raw data in the duplicated figure backed up its conclusions, “given the nature and extent of data manipulation,” the authors asked the journal to retract the paper .

Continue reading Investigation ends in 6th retraction for Voinnet

PLOS Genetics updates flagged paper with expression of concern

Screen Shot 2015-09-15 at 2.15.29 PM

PLOS Genetics has upgraded a notice on a paper to an expression of concern, raising the count for author chemist Ariel Fernandez to one retracted paper, and three expressions of concern.

The journal published “Protein Under-Wrapping Causes Dosage Sensitivity and Decreases Gene Duplicability” in 2008. In 2013, Fernandez corrected it, claiming that the work was not actually funded by the U.S. National Institutes of Health, as the original paper had said. The paper has been cited 33 times, according to Thomson Scientific’s Web of Knowledge.

Here’s the expression of concern in full, which was published on September 14:

Continue reading PLOS Genetics updates flagged paper with expression of concern

When the title states the wrong result, a paper gets corrected

PLOS ONE

Ever wonder why, on a round-trip, the leg home often feels shorter? A group of researchers found that’s only true in hindsight, as people look back on which leg felt shorter — the trouble is, when the paper first appeared, the title mistakenly stated the opposite was true.

One June 10, PLOS ONE published a paper entitled “The Return Trip Is Felt Longer Only Postdictively: A Psychophysiological Study of the Return Trip Effect”; 17 days later, it was republished under the correct title, “The Return Trip Is Felt Shorter Only Postdictively: A Psychophysiological Study of the Return Trip Effect.”

On July 15, the journal posted a correction notice explaining its mistake:

Continue reading When the title states the wrong result, a paper gets corrected