Category: pharmacology

When a paper is retracted, so is its previous correction–sometimes

1-s2.0-S0968089612X0018X-cov150hSometimes, the path to correcting the scientific record takes a few turns. In the case of a paper about a new cancer compound, authorship issues led to a correction and, ultimately, a retraction — along with a double-back to retract the earlier correction.

We reported on the first part of the story back in January: A 2011 paper that described a novel compound that could work as a drug for the side effects of chemotherapy was corrected in 2012 to add additional authors. But once the authors realized their supposedly novel compound had actually been synthesized by another author, they decided to retract the paper from Bioorganic and Medicinal Chemistry earlier this year, concluding “these facts made the paper inappropriate and unfaithful.”

Apparently, around the same time, the authors decided to retract the earlier correction, as well:

Continue reading When a paper is retracted, so is its previous correction–sometimes

U Colorado “golden boy” grad student faked data in drug lab, says investigation

u coloradoA graduate student at the University of Colorado Denver faked data in his work at a drug research lab that has notched two retractions and an expression of concern over “data integrity,” according to an extensive university investigation.

It seems like many more retractions are on the horizon for grad student Rajendra Kadam, who worked in the lab of Uday Kompella, a pharmaceutical researcher at the university.  

Here’s an excerpt from the report, which you can read in full (but redacted) here: Continue reading U Colorado “golden boy” grad student faked data in drug lab, says investigation

Takeda group retracts paper after realizing “novel” compound had already been synthesized…by a colleague

BMC_CoverA group of scientists at Takeda Pharmaceutical, including vice president Yoshinori Ikeura, has lost a paper after realizing that their “novel” compound had been previously synthesized by another Takeda researcher.

The 2011 paper, published in Elsevier journal Bioorganic & Medicinal Chemistry, was the subject of a 2012 corrigendum adding two authors to the paper. The retraction appeared online in December of this year.

Seems like they didn’t add enough authors, though. Continue reading Takeda group retracts paper after realizing “novel” compound had already been synthesized…by a colleague

Hospital in India wracked by allegations of scientific misconduct, poor sanitation

jcdrThree doctors at the Post Graduate Institute of Medical Education and Research (PGIMER) in Chandigarh are losing a paper based on phone calls to the Drug Information Unit, a phone line that patients could call to learn more about the drugs they were considering taking.

The catch: It was all made up.

According to an investigation by the Hindustan Times, the phone was disconnected between 2012 and May 2014, though ‘data’ for the paper was allegedly collected in 2013. We imagine that would make it difficult to answer the 56 calls the paper claims a junior resident took over the course of a month.

The HT reports that the Journal of Clinical & Diagnostic Research paper, “Drug Information Unit as an Effective Tool for Promoting Rational Drug Use,” is being retracted, and that the dean has asked for an official investigation. We’ve reached out to the journal, and will update with any new information.

This isn’t the worst of recent allegations against hospital staff at PGIMER. Orthopedics professor Vishal Kumar was accused of being in bed with pharmaceutical companies and harassing several employees. From the HT: Continue reading Hospital in India wracked by allegations of scientific misconduct, poor sanitation

Psych paper falls afoul of journal’s plagiarism policy (hint: don’t plagiarize)

jcpharmacopharmThe Journal of Clinical Psychopharmacology has retracted a 2011 paper on depersonalization disorder by a pair of authors in Azerbaijan who got a bit too familiar with their source material without proper attribution. And the journal has offered its readers a handy — if depressingly obvious — admonition about publication ethics.

The article, “Lamotrigine in the immediate treatment of outpatients with depersonalization disorder without psychiatric comorbidity. Randomized, double-blind, placebo-controlled study,” by researchers at the Central Mental Clinic for Outpatients of Baku City, purported to find that: Continue reading Psych paper falls afoul of journal’s plagiarism policy (hint: don’t plagiarize)

It’s happened again: Researcher appears to have peer reviewed his own paper

bmc sys bioAlthough it shocks some observers every time, we’ve reported on the retractions of more than 100 papers pulled because authors managed to do their own peer review.

Apparently, it’s happened again.

Here’s a retraction notice in BMC Systems Biology for “Predicting new molecular targets for rhein using network pharmacology,” by  Aihua Zhang, Hui Sun, Bo Yang and Xijun Wang:

Continue reading It’s happened again: Researcher appears to have peer reviewed his own paper

Journal that “suffered” from plagiarism purges itself

pharmpractWhen Pharmacy Practice found out it had been victimized by plagiarists, it apparently took the news personally — and to heart.

In an elaborate statement with more than a dozen references — but not one to the plagiarizing work — the journal lashed out against the behavior of word thieves, and described the discovery as a Road to Damascus moment.

Here’s the notice, which was published in 2012 but was only just indexed on PubMed:

Continue reading Journal that “suffered” from plagiarism purges itself

“Error in data compilation” leaves bitter taste for paper on sweeter-tasting pills

A publication on a new, tastier dissolving tablet has been retracted for data errors. Here’s the brief notice for “Meloxicam Taste-Masked Oral Disintegrating Tablet with Dissolution Enhanced by Ion Exchange Resins and Cyclodextrin“: Continue reading “Error in data compilation” leaves bitter taste for paper on sweeter-tasting pills

Drug journal jumps the gun on publishing response to comment

annals of pharmThis one’s a little circular: The Annals of Pharmacotherapy, a SAGE journal, has retracted an author’s response to a letter to the editor that was never published. The original paper, “Intravenous sodium bicarbonate therapy in severely acidotic diabetic ketoacidosis,” is unaffected by the retraction.

According to the notice: Continue reading Drug journal jumps the gun on publishing response to comment

Integrity of data “undisputed” in paper pulled for plagiarism

ijpharI shot the sheriff
But I didn’t shoot no deputy, oh no! Oh!
I shot the sheriff
But I didn’t shoot no deputy, ooh, ooh, oo-ooh.

—Bob Marley

A group of pharmacologists in Japan has retracted their 2012 article in the International Journal of Pharmaceutics for plagiarism. But not, they note, for any other reason.

The article, “Suppression of efflux transporters in the intestines of endotoxin-treated rats,” came from researchers in the Department of Drug Absorption and Pharmacokinetics in the School of Pharmacy at Tokyo University of Pharmacy and Life Sciences. It has been cited once, according to Thomson Scientific’s Web of Knowledge.

Continue reading Integrity of data “undisputed” in paper pulled for plagiarism