When Nature published a paper in 2011 describing a compound extracted from a pepper plant that appeared to kill cancer cells but leave healthy cells unscathed, it got some attention.
Of course, the news caught the media’s eye, but also that of other researchers, who have since jumped on the concept, and continued to study the effects of the compound — piperlongumine — on cancer, as well as other conditions.
But ever since the 2011 letter appeared, researchers have raised concerns about some of the figures — including one that showed mice with massive tumors, suggesting they had experienced an unreasonable amount of distress during the study. Nature has responded by issuing two lengthy correction notices in 2012 and 2015 — as well as an editorial that admitted the animals may have “experienced more pain and suffering than originally allowed for,” but did not warrant retracting, as the results remained “valid and useful.”
Today, the journal is retracting the paper, with the following brief notice:
Continue reading Nature cancer paper that raised animal welfare concerns is retracted


How long should a retraction take?
Many publishers have been duped by fake peer reviews, which have brought down more than 600 papers to date. But some continue to get fooled.
In April 2015, two high-profile chemistry bloggers — and their commenters — raised questions about a paper that had been published in PLOS ONE some 18 months earlier. More than three years later, the journal has now retracted the paper, with a notice that echoes the 2015 blog posts.
Researchers have retracted a 2015 Nature paper about the molecular underpinnings of immune function after discovering they could not replicate key parts of the results.
Barislav Momčilović thinks that iodine status is — after iron deficiency — the “main public health” issue in the world today. So when he figured out what he believed was the best way to test levels of the mineral, he was determined to get the message out.
Last year,
In March, a journal published a paper about blood sugar levels in newborns that caused an immediate outcry from outside experts, who were concerned it contained a sentence that could be potentially harmful if misinterpreted by doctors.