Now-retracted chem paper’s problems “should have been noticed by the referees,” group says

Last year, chemist Marcus Tius at the University of Hawaii saw a paper describing the synthesis of some organic compounds, and was “struck by the implausibility” of the reported structures. So he joined up with some colleagues to try to replicate the data.

While Tius and his team were trying to repeat the experiment, however, in December 2017 the journal — Organic Letters — retracted the paper. The journal, published by the American Chemical Society, noted that the authors had not been able to produce crystal structures that confirm they had synthesized those compounds in particular. So Tius and his colleagues knew they couldn’t replicate the findings — but carried on their experiment anyway:

Continue reading Now-retracted chem paper’s problems “should have been noticed by the referees,” group says

Caught Our Notice: A paper mistakenly ID’d a patient. Its retraction notice did, too. (Oops!)

What Caught Our Attention: Last year, a journal retracted a paper about a child who developed a rare complication related to the inherited disorder Gaucher Disease, after realizing it had inadvertently identified the child. It wasn’t an immediately obvious mistake — the authors listed the drugs the patient was taking, and in the case of one drug, there was only one child in the world taking it. For anyone in the know, that would make the child’s identity clear.

So retracting the paper makes sense — but publishing a retraction notice that spells out the issue in detail, including the name of the drug and the fact the patient was the only pediatric recipient, did not. So last month, the Journal of Pediatric Hematology/Oncology corrected the retraction notice, removing the name of the drug. (Phew.)

Continue reading Caught Our Notice: A paper mistakenly ID’d a patient. Its retraction notice did, too. (Oops!)

Caught Our Notice: A team from Harvard, Cornell, Cambridge, HHMI, and UCSF can’t reproduce a paper’s findings

What Caught Our Attention: Any time there’s an issue with a paper co-authored by researchers from such high-profile institutions as Harvard, Cornell, and the University of Cambridge, we take notice. In this case, the group — which included Laurie Glimcher, then-dean at Cornell, now president of the Dana-Farber Cancer Institute — chose to retract a 2013 paper from a Cell journal after learning they couldn’t reproduce some of the experiments. Continue reading Caught Our Notice: A team from Harvard, Cornell, Cambridge, HHMI, and UCSF can’t reproduce a paper’s findings

Caught Our Notice: Hey peer reviewers — did you even read this paper??

What Caught Our Attention: A tree of life paper has been axed — and based on the information in the retraction notice, we’re wondering how it ever passed peer review.

Specifically, the notice states a review of the paper found “concerns regarding the study design, methodology, and interpretation of the data.” Overall, the research “contradict(s) a large body of existing literature and do(es) not provide a sufficient level of evidence to support the claims made in the paper.” Um, so what did it get right?

Continue reading Caught Our Notice: Hey peer reviewers — did you even read this paper??

Mount Sinai multiple sclerosis researcher admits to misconduct

Gareth John

A researcher who has received millions in funding from the U.S. National Institutes of Health and who runs a lab at the Icahn School of Medicine at Mount Sinai in New York has confessed to falsifying data in a 2014 paper.

Gareth John, who studies multiple sclerosis and other neurological diseases, “has expressed remorse for his actions,” according to a report released last week from the U.S. Department of Health and Human Services’ Office of Research Integrity. Continue reading Mount Sinai multiple sclerosis researcher admits to misconduct

One team’s struggle to publish a replication attempt, part 3

Mante Nieuwland

Which journals will publish replications? In the first post in this series, Mante Nieuwland, of the Max Planck Institute for Psycholinguistics, described a replication attempt of a study in Nature Neuroscience that he and his colleagues carried out. Yesterday, he shared the story of their first submission to the journal. In the final installment today, he explains why the paper was eventually published in another journal. Continue reading One team’s struggle to publish a replication attempt, part 3

An attempt to publish a replication attempt in a Nature journal, part 2

Mante Nieuwland

Do journals walk the walk when it comes to publishing replications? In the first installment in this series of guest posts, Mante Nieuwland, of the Max Planck Institute for Psycholinguistics, described a replication attempt of a study in Nature Neuroscience that he and his colleagues carried out. Today, he shares the story of their first submission to the journal. Continue reading An attempt to publish a replication attempt in a Nature journal, part 2

Nature says it wants to publish replication attempts. So what happened when a group of authors submitted one to Nature Neuroscience?

Mante Nieuwland

Over the past few years, Nature has published editorials extolling the virtues of replication, concluding in one that “We welcome, and will be glad to help disseminate, results that explore the validity of key publications, including our own.” Mante Nieuwland, of the Max Planck Institute for Psycholinguistics, and colleagues were encouraged by that message, and submitted one such replication attempt to Nature Neuroscience. In a three-part guest post, Nieuwland will describe what happened when they did, and discusses whether reality lives up to the rhetoric. Here’s part one: Continue reading Nature says it wants to publish replication attempts. So what happened when a group of authors submitted one to Nature Neuroscience?

A frustrated former editor asked a publishing group for help. He didn’t like what they said.

When the former editor of a public health journal didn’t get a straight answer about why the journal retracted his paper that was critical of corporate-sponsored research, he brought his concerns to an organization dedicated to promoting integrity in academic publishing. He wanted the group to help resolve the impasse he’d reached with the publisher, but was sorely disappointed.

David Egilman, the former editor of the International Journal of Occupational and Environmental Health, had been seeking answers about the paper for a year. In November, the journal’s editorial board resigned, in protest of the “apparent new direction that the journal appears to be moving towards.” They objected to the “unilateral withdraw[al]” of Egilman’s paper, with little explanation, the delay in publishing other papers that had been accepted under Egilman’s leadership, and the decision to appoint a new editor with industry ties.

Amidst all that upheaval at the journal, Egilman still wasn’t getting the answers he wanted about why his paper was withdrawn. So he brought his concerns to the Committee on Publication Ethics (COPE).

Continue reading A frustrated former editor asked a publishing group for help. He didn’t like what they said.

When multiple doctors treat a patient, who gets to publish the case report?

Three researchers are fighting over who should get to publish a case report on a pair of unique patients.

Yoo-Mi Kim—who was not an author on the paper—claimed that he had diagnosed the patients described in the report, and should have been the one to write it up. The authors—Jun Woo Park and Soo Jung Lee—disagreed, claiming that they had treated the patients for years and had received oral consent from the patients to publish the report.

The Journal of American Association for Pediatric Ophthalmology and Strabismus, unable to resolve the disagreement, has published an expression of concern highlighting the dispute. Continue reading When multiple doctors treat a patient, who gets to publish the case report?