Former rising star found guilty of misconduct issues 2nd retraction

A once-lauded researcher in the field of infectious disease — who has since been found guilty of misconduct — has retracted a second paper.

Last year, the University of Dundee in Scotland investigated and ultimately concluded that Robert Ryan — whose work focused on infections that can be deadly in people with lung diseases such as cystic fibrosis — had committed “serious research misconduct,” affecting multiple publications. After appealing the decision, Ryan resigned.

We covered his first retraction earlier this month, which cited multiple instances of image duplication. Now Ryan has retracted his second paper, published in 2011 in Journal of Bacteriology, also due to image problems.

Here’s the retraction notice: Continue reading Former rising star found guilty of misconduct issues 2nd retraction

E. coli gene paper falls to mistaken mutation

asmcoverResearchers in Germany have retracted their 2011 article in the Journal of Bacteriology after another lab pointed out a fatal error in the paper.

The article, “Escherichia coli Exports Cyclic AMP via TolC,” came from a group at Tübingen University led by Klaus Hantke. The paper focuses on the crucial role of the membrane channel TolC in exporting cyclic AMP (cAMP)-cAMP receptor protein (CRP) complex, which regulates nearly 200 E. coli genes. According to the abstract:

The data demonstrate that export of cAMP via TolC is a most efficient way of E. coli to lower high concentrations of cAMP in the cell and maintain its sensitivity in changing metabolic environments.

But the conclusions rested on a gene mutation that wasn’t quite what it seemed. Here’s the notice: Continue reading E. coli gene paper falls to mistaken mutation

Post-doc fired after explaining image problems in paper to Retraction Watch

Christian Ramos
Christian Ramos

We reported last week on a Portuguese group that lost two papers over mislabeled image files.

Now, we’ve learned that first author Christian Ramos has been fired after speaking to Retraction Watch and offering what seemed like a heartfelt apology (which you can read here). Continue reading Post-doc fired after explaining image problems in paper to Retraction Watch

“This situation left me ashamed and infuriated with myself:” Scientist retracts two papers

j bacteriologyA Portuguese group has retracted two papers in the Journal of Bacteriology after mislabeled computer files led to the wrong images being used.

And, we’ve learned in a heartfelt email, the first author was devastated.

Here’s the notice for “MtvR Is a Global Small Noncoding Regulatory RNA in Burkholderia cenocepacia”: Continue reading “This situation left me ashamed and infuriated with myself:” Scientist retracts two papers

Two Journal of Bacteriology papers retracted for data duplication spanning five years

j bacteriolA group of bacteria researchers in Spain and Germany has lost two papers in the Journal of Bacteriology after the journal found evidence that they had reused figures.

The two notices, for “Heat Shock Proteome Analysis of Wild-Type Corynebacterium glutamicum ATCC 13032 and a Spontaneous Mutant Lacking GroEL1, a Dispensable Chaperone” and “Transcriptional Analysis of the groES-groEL1, groEL2, and dnaK genes in Corynebacterium glutamicum: Characterization of Heat Shock-Induced Promoters,” say the same thing: Continue reading Two Journal of Bacteriology papers retracted for data duplication spanning five years

Journal retracts protein paper from scientist who misused deceased mentor’s data

It seemed like a touching tribute when Jiasheng Diao dedicated his 2009 article, “Crystal Structure of Butyrate Kinase 2 from Thermotoga maritima, a Member of the ASKHA Superfamily of Phosphotransferases,” in the Journal of Bacteriology to a deceased mentor, Miriam Hasson.

Before her death in January 2006, of a brain tumor, Hasson and her husband, David Sanders, made up a power-team of protein researchers at Purdue.

Hasson was an X-ray crystallographer while Sanders is a biochemist, and together they would map out the structure and function of proteins. One of their projects  was a  collaboration funded by a grant to Sanders from the National Science Foundation. By the time Diao joined, the effort had already led to butyrate-kinase crystals — albeit of poor quality, Sanders said.

When Hasson died, Sanders — with his institution’s blessing — took control of her data. That made sense, since their labs had collaborated closely. Indeed, they occasionally shared post-docs, including Diao, who had started with Hasson on a project looking at a protein called butyrate kinase but then moved over to Sanders’ lab as the work evolved. Continue reading Journal retracts protein paper from scientist who misused deceased mentor’s data