int j obesity – Retraction Watch

Journal retracts GLP-1 study after researcher questions central finding

After reading a recent study about GLP-1 treatment in the International Journal of Obesity, David B. Allison immediately became skeptical about the paper’s analysis. The article, published in May 2024, found people who combined a GLP-1 therapy with another weight loss drug lost more weight than patients on a GLP-1 therapy alone.

“I could not really comprehend exactly what analysis they did,” Allison, chief of nutrition and director of the Children’s Nutrition Research Center at Baylor College of Medicine in Houston, told Retraction Watch. “And more so, I could not comprehend how the analysis they did would give results that would be informative of the conclusions they drew. So I was scratching my head a little bit.”

The IJO paper was a retrospective cohort study of adults with obesity who had been prescribed a GLP-1 therapy, specifically Saxenda and Ozempic. The study compared patients who received a GLP-1 alone with those receiving the GLP-1 therapy and then had bupropion/naltrexone added to their regimen. The Food and Drug Administration approved bupropion/naltrexone in 2014 for chronic weight management in obese adults.

Authors who lost paper linking fecal transplants to obesity have another retracted

An obesity journal has retracted a study by authors who previously lost another paper that suggested a link between the fecal microbiome and obesity.

We first came across on the now-retracted paper in the International Journal of Obesity (IJO) in April when we reported on the authors’ other retraction in Diabetes. The 2014 paper had a corrigendum, published the same year, and also for image-related issues. Since then, however, the journal has pulled the IJO paper and its associated corrigendum at the request of the French National Institute of Agronomic Research (INRA) in Paris. Continue reading Authors who lost paper linking fecal transplants to obesity have another retracted

Paper linking fecal transplants to obesity in rats retracted for faked data

A paper linking the fecal microbiome to obesity has been retracted after it became clear that one of the co-authors faked some of the data.

The 2014 paper in Diabetes — which found that rats given fecal transplants from obese mice were more likely to become obese themselves if given a particular diet — was pulled after after an institutional investigation found a co-author guilty of falsifying data underlying one figure and fabricating the data of two others.

Co-author Yassine Sakar — formerly based at the French National Institute of Agronomic Research (INRA) in Paris, France — was found responsible for the misconduct. But an official from the institution said that some responsibility must also be shared by the corresponding author Mihai Covosa, who has since resigned from the institution.

Here’s the retraction notice: Continue reading Paper linking fecal transplants to obesity in rats retracted for faked data

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