A journal says it will retract a 2019 paper on an Alzheimer’s treatment after an institutional investigation found research misconduct, according to emails seen by Retraction Watch. The move comes four years after another investigation by the same university uncovered image duplication in a different paper by a similar group of authors.
The paper, published in Biological Psychiatry, describes the potential of an apoE antagonist for treatment in Alzheimer’s disease.
A 2019 news release by the University of South Florida, home to several of the researchers involved in the study, called the work “promising.” Lead author Darrell Sawmiller, an assistant professor at USF, said the study represented “the first time … we have direct evidence” apoE “acts as an essential molecule” in the mechanisms leading to Alzheimer’s.
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