Category: united states

Journal alerts readers to “technical criticism” of CRISPR study

A Nature journal has posted a editor’s note to a recent letter on potential unintended consequences of CRISPR gene editing, after an executive at a company trying to commercialize the technology said the paper should be retracted.

The original article, published on May 30 as a correspondence in Nature Methods, suggested that using CRISPR in mice can lead to unexpected mutations. But last week, the journal added an “Editorial note” online. Nature Methods says the notice is not an expression of concern, which would be a stronger suggestion that the paper is problematic; it simply wants to alert readers to the fact that, as the note states:

Continue reading Journal alerts readers to “technical criticism” of CRISPR study

Big corrections usually weaken findings. But a recent NEJM one strengthened them, author says

A 2016 study in New England Journal of Medicine has received a substantial correction, which affected several aspects of the article.

Typically, an error that affects so much of a paper would undermine the results (and possibly lead to a retraction). But in this case, the revised dose calculations actually strengthened the findings, according to the first author.

The NEJM study aimed to clarify whether patients with a neuromuscular disease called myasthenia gravis benefit from a surgical procedure to remove the thymus. About half of the patients received surgery plus the steroid prednisone, while the rest only received the steroid. The researchers found patients who received the surgery fared better.

Shortly after the paper was published in August 2016, the authors discovered an error in the calculation of the average prednisone dose. According to Gil Wolfe, the first author of the paper, when the researchers corrected the error: Continue reading Big corrections usually weaken findings. But a recent NEJM one strengthened them, author says

NIH researcher doctored 11 figures in 2016 paper, says ORI

A former Research Training Awardee at the National Institutes of Health “falsified and/or fabricated data” in 11 figures in a 2016 paper, according to the U.S. Office of Research Integrity.

This is the first finding of misconduct issued this year by the ORI.

According to the finding, published in the Federal Register, Brandi M. Baughman — formerly at the National Institute of Environmental and Health Sciences (NIEHS) — tweaked data and text in a PLOS ONE paper about screening for compounds that inhibit an enzyme known as inositol phosphate kinase. According to the notice, however, some of those experiments didn’t proceed as described:

Continue reading NIH researcher doctored 11 figures in 2016 paper, says ORI

Former prof fudged dozens of images, says university

On Dec. 2, 2013, Alison Lakin, the research integrity officer at the University of Colorado Denver, received a concerning email.

The emailer was alleging several problems in a 2012 paper in the Journal of Clinical Investigation, co-authored by one of its high-profile faculty members. Lakin discussed the allegations with some administrators and agreed they had merit; Lakin sequestered an author’s laptop and other materials. Over the next few months, the university learned of additional allegations affecting other papers — and discovered even more serious problems in the JCI paper. Namely, the first author had inserted changes to 21 figures in the paper after submitting it, without alerting the other authors, journal, or reviewers.

That journal retracted the paper this month, citing numerous problems:

Continue reading Former prof fudged dozens of images, says university

Following outcry, American Psychological Association “refocuses” takedown notice program

After a deluge of protests from researchers who received notices from the American Psychological Association (APA) to remove papers from their websites, the publisher announced it will shift its focus to commercial sites.

Earlier this week, researchers took to Twitter to lament the takedown notices they had received from the APA; one posted the letter in place of his paper. The letters were part of a pilot program by the APA to remove “unauthorized online postings of APA journal articles.”

That program has now taken a bit of a turn. In a release yesterday, the APA says that:

Continue reading Following outcry, American Psychological Association “refocuses” takedown notice program

Career derailed, ex-prof to sue Montana State for wrongful termination

Ryan Jones. Credit: Kelly Gorham/MSU

A former assistant professor at Montana State University who was fired last year is planning to sue the school for defamation, wrongful termination, and violation of due process.

Ryan Jones, a microbiologist, was forced to leave his tenure-track position — which was technically a one-year contract, so could be terminated before he had the opportunity to apply for tenure. The case highlights the insecurity of non-tenured academic jobs, an issue the planned suit is tackling head on. In addition to monetary damages, the lawsuit seeks to void all one-year contracts at Montana State, which can be terminated for any reason — a system that exists elsewhere in academia.

Jones told Retraction Watch that he believes he was forced out based on what he alleges are cooked-up charges of research misconduct — specifically, he brought back insect samples from the Amazon but didn’t fill out a permit:

Continue reading Career derailed, ex-prof to sue Montana State for wrongful termination

Researchers protest publisher’s orders to remove papers from their websites

Researchers are protesting orders from the American Psychological Association to remove links to papers from their websites.

Multiple researchers took to Twitter recently to lament the takedown notices they’ve received from the APA; one posted the letter in place of the link to his paper. According to the APA, the letters are part of a pilot program to “monitor and seek removal of unauthorized online postings of APA journal articles.”

The notices cite misuse of the Digital Millennium Copyright Act (DMCA), which enables internet users to protect their own content. But it can be heavily abused by people who file false copyright infringement claims to remove content they don’t like from the internet. (We have even been the target of such attempts.)

According to the letter posted by Nathaniel Daw at Princeton University, the APA says:

Continue reading Researchers protest publisher’s orders to remove papers from their websites

Ohio State exercise researcher resigns after retraction of CrossFit study

The senior author of a lawsuit-spawning study of the CrossFit exercise program has resigned from his post at The Ohio State University.

On June 2, we reported that the Journal of Strength and Conditioning Research retracted the problematic study because it lacked approval from the institutional review board. The journal had previously corrected the study, acknowledging it contained false injury statistics.

Now, an OSU spokesperson has confirmed that — as first reported by the Columbus Dispatch — former assistant associate professor Steven Devor resigned May 31, the day after the retraction.

The spokesperson also confirmed that OSU made several demands following an investigation into the CrossFit study: That Devor either correct or retract the study, that he take a 33 percent pay cut for the rest of the year, and that he refrain from both serving as a principal investigator and  contacting graduate students as long as he remained there.

Continue reading Ohio State exercise researcher resigns after retraction of CrossFit study

OSU researcher under investigation corrects paper cited 500 times

An EMBO journal has issued a correction for a well-cited 2012 review co-authored by a cancer researcher under investigation.

Carlo Croce, the last author on the review, has been beleaguered by misconduct accusations that have followed him for years (recently described in a lengthy article in the New York Times), and his university has recently re-opened an investigation into his work.

By our count, Croce — based at The Ohio State University — has logged six retractions, along with multiple expressions of concerns and corrections. The latest correction, in EMBO Molecular Medicine, notes the review lifted passages from multiple publications — and was in turn reused in later papers, as well.

Here’s the notice:

Continue reading OSU researcher under investigation corrects paper cited 500 times

Journal won’t look at allegations about papers more than six years old, nor comment on those from “public websites”

After a paper is published, how long should a journal consider allegations of misconduct? For one journal, that answer is: Six years.

We see plenty of journals that retract papers at least 10 years old over concerns regarding misconduct, but in a recent editorial, Molecular and Cellular Biology announced it would pursue allegations made within six years after a paper is published. This rule mirrors federal regulations (which apply to the U.S. Office of Research Integrity), which also decline to investigate allegations if at least six years have passed since the incident supposedly occurred — but with some exceptions, such as if the misconduct could have an impact on public health.

Incidentally, the same issue of the journal includes a retraction notice for a paper published seven years ago, citing image duplications. A spokesperson for the American Society for Microbiology (which publishes the journal) told us the journal investigated the paper in 2016, within the cutoff period.

Here’s the key text from the editorial:

Continue reading Journal won’t look at allegations about papers more than six years old, nor comment on those from “public websites”