Category: united states

Update on Anil Potti: A patient in a trial based on retracted research speaks out; Baggerly on how to prevent the next fiasco

courtesy Duke

A quick post this Sunday morning to draw your attention to two must-read items for anyone interested in the Anil Potti case or in how one goes about checking data. (A second paper by Potti et al was officially retracted on Friday.)

First, a terrific profile of Joyce Shoffner in the Charlotte News & Observer. Shoffner

was one of 110 Duke patients enrolled in three clinical trials based on the research of Dr. Anil Potti, who resigned in November as an associate professor at Duke.

Here at Retraction Watch, we obviously think all retractions are worth following. But we hope this story will convince those who shrug and say such items are inside baseball, or “none of your damn business,” that they need to re-evaluate their positions. This is where the rubber hits the road: Continue reading Update on Anil Potti: A patient in a trial based on retracted research speaks out; Baggerly on how to prevent the next fiasco

Nature Medicine makes it official, retracting Anil Potti paper

 

courtesy Nature

Nature Medicine has retracted a paper that Anil Potti’s co-author, Joseph Nevins, requested be withdrawn in November.

This is the second retraction of a paper by Potti, who resigned from his post at Duke in November in the midst of an investigation into scientific misconduct. The first retraction was in the Journal of Clinical Oncology.

According to the Nature Medicine retraction notice: Continue reading Nature Medicine makes it official, retracting Anil Potti paper

Authors of Journal of Immunology paper retract it after realizing they had ordered the wrong mice

The authors of a 2006 Journal of Immunology study have retracted it after it dawned on them that they used the wrong mice.

The study, “Endogenous IL-1R1 Signaling Is Critical for Cognate CD41 T Cell Help for Induction of In Vivo Type 1 and Type 2 Antipolysaccharide and Antiprotein Ig Isotype Responses to Intact Streptococcus pneumoniae, but Not to a Soluble Pneumococcal Conjugate Vaccine,” has been cited 11 times, according to Thomson Scientific’s Web of Knowledge.

According to the retraction notice: Continue reading Authors of Journal of Immunology paper retract it after realizing they had ordered the wrong mice

Why was that paper retracted? Editor to Retraction Watch: “It’s none of your damn business”

L. Henry Edmunds, photo by University of Pennsylvania

Yesterday, we reported on the retraction of a 2004 study in the Annals of Thoracic Surgery. As we noted, the notice’s language was, um, fuzzy, referring vaguely to

an investigation by the University of Florida, which uncovered instances of repetitious, tabulated data from previously published studies.

Today, we are slightly more clear, although what we really got was an earful of other language.

We had the pleasure of speaking this morning with L. Henry Edmunds, Jr., the long-time editor of the Annals of Thoracic Surgery, who gave us a better sense of why his retraction notice was so delicately worded. Edmunds, responding to question of why the letter didn’t say more about the matter:

It’s none of your damn business.

Ranting against “journalists and bloggists,” Edmunds, a cardiac surgeon at the University of Pennsylvania, said the purpose of the retraction notice was merely Continue reading Why was that paper retracted? Editor to Retraction Watch: “It’s none of your damn business”

Thoracic surgery journal retracts hypertension study marred by troubled data

The Annals of Thoracic Surgery has retracted a 2004 article by a group of Florida researchers who were found by their university to have misrepresented the provenance of their data.

If that construction sounds a trifle precious (er, weasel-y), that’s because the retraction notice does, too: Continue reading Thoracic surgery journal retracts hypertension study marred by troubled data

Update on Small retraction: Co-author says failed follow-up led to detection of tech’s fraud

We have a little more information on the lab-tech case out of the University of Chicago that we reported on last week. A brief summary: The journal Small retracted a 2007 paper on a method of producing insulin-secreting cells after one of the co-authors, a technician named Matthew Connors, was found to have fabricated a key figure. Connors has had a long career as a lab tech and his name has appeared on several published articles.

Reached by e-mail, Milan Mrksich, a chemistry professor at Chicago and a co-author of the retracted paper– as well as an investigator for the Howard Hughes Medical Institute — told us that the fraud surfaced during follow-up research: Continue reading Update on Small retraction: Co-author says failed follow-up led to detection of tech’s fraud

Small problem: Nano-micro journal pulls diabetes paper with phony figure

Readers of this blog are aware that many of the retractions we’ve covered involve the misadventures of post-docs. That makes some superficial sense: post-docs, after all, are trainees, and therefore might be more likely to make mistakes. They’re also hungry to break into their chosen specialty, and how better to do that than by producing spectacular results? (None of this is to say that post-docs are by nature incompetent or venal — only that the raw ingredients exist for typecast villainy.)

But one figure about whom we haven’t written (to the best of our knowledge) is the career lab tech — until today.

Matthew Connors was working as a tech at the University of Chicago (Chief Research Technologist, on his online resume) when he became a co-author on a 2007 study, published in the journal Small, purporting to show a technique for encapsulating pancreatic islet cells in a coating that’s opaque to the immune system. As the researchers explained: Continue reading Small problem: Nano-micro journal pulls diabetes paper with phony figure

Obfuscation watch: Self-plagiarism (we think) leads to retraction of nanorod paper in Applied Physics Letters

C. P. Snow famously bemoaned the gulf between science and the humanities. The following retraction might be the sort of thing that would have given the physicist-cum-author fits for its estrangement from the English language.

Writing in the latest issue of Applied Physics Letters, a team from China Singapore and MIT appear to be confessing a case of self-plagiarism in their 2005 paper, “Growth of single crystal ZnO nanorods on GaN using an aqueous solution method: (we added a link to the earlier paper)” Continue reading Obfuscation watch: Self-plagiarism (we think) leads to retraction of nanorod paper in Applied Physics Letters

Penalties for early withdrawal: irked CONSORT Group authors

Premature withdrawal can lead to frustration and hurt feelings — especially when it comes to publications (please, this is a family-friendly site).

Two cases in point: We recently learned that the International Journal of Surgery, an Elsevier title, had withdrawn two papers from the CONSORT group — an acronym for Consolidated Standards of Reporting Trials — an international team of scientists who have been working on ways to improve the reporting of studies.

In 2008, they published a paper titled “Methods and processes of the CONSORT Group: example of an extension for trials assessing nonpharmacologic treatments” in the Annals of Internal Medicine. They followed up in March 2010 with the publication of “CONSORT 2010 Statement: Updated guidelines for reporting parallel group randomized trials.”

As they wrote in the statement: Continue reading Penalties for early withdrawal: irked CONSORT Group authors

Journal will remove fake cardiologist William Hamman’s credentials, but paper will remain in print

Earlier this week, we asked what is likely to happen to papers published by William Hamman, the United pilot who claimed — falsely — to also be a cardiologist. Read more about the episode here.

One of the journals in which Hamman published, the American Journal of Medical Quality, will “amend the paper to correct” Hamman’s credentials — or lack thereof, a journal staffer told us today. The journal hasn’t dealt with this sort of thing before, so is checking with the publisher before making the change. They “plan to get it done as quickly as they can do it.”

We haven’t seen this sort of thing either. Continue reading Journal will remove fake cardiologist William Hamman’s credentials, but paper will remain in print