Category: united states

Why did Science partially retract the XMRV-chronic fatigue syndrome paper?

If past experience is any indication, billions of pixels will be spilled in the coming days as scientists and advocates debate the latest twist in the story of XMRV, or xenotropic murine leukemia-related virus, and chronic fatigue syndrome (CFS). Today’s news is that Science is partially retracting a 2009 paper by Judy Mikovits and colleagues, including Vincent Lombardi, purporting to show a link between the virus and the syndrome — a paper about which they issued an Expression of Concern in May. The retraction is of a table and a figure — more on that in a bit.

In an excellent blow-by-blow account in Science of the nearly 20-year-long saga, also out today, Jon Cohen and Martin Enserink review the unusual circumstances of that Expression of Concern. Science editor-in-chief Bruce

Alberts and Science Executive Editor Monica Bradford had first suggested that Mikovits and her co-authors retract the paper voluntarily. “Science feels it would be in the best interest of the scientific community,” they wrote in a 26 May letter. Mikovits was livid and questioned Alberts’s motives. “Who wrote that letter? I don’t think it was Science,” she says. The co-authors thought the retraction request was premature, too. “What if we walk away from this based on contamination and it’s not contamination?” Lombardi asked. “You’ve got to give us time to figure this out.”

Alberts stresses that they floated the retraction idea because Science already planned to publish the Expression of Concern. “It wasn’t a public call for retraction,” he notes, emphasizing that the recipients shared it with the media. He also does not think it would have been premature, although he says it’s often a tough call whether to retract a paper. “Ultimately, it requires expert judgment and a lot of sensitivity to the issues,” he says. “We had lost confidence in the results.”

As Science noted in May, two studies accompanied the May Expression of Concern Continue reading Why did Science partially retract the XMRV-chronic fatigue syndrome paper?

Potti retraction tally grows to six with a withdrawal in PLoS ONE, and will likely end up near a dozen

Anil Potti and his former Duke colleagues have retracted a sixth paper, this one in PLoS ONE.

According to the retraction notice for “An Integrated Approach to the Prediction of Chemotherapeutic Response in Patients with Breast Cancer,” the withdrawal was prompted by the retraction of a Nature Medicine paper that formed the basis of the PLoS ONE study’s approach: Continue reading Potti retraction tally grows to six with a withdrawal in PLoS ONE, and will likely end up near a dozen

Publishing scandal costs nursing researcher his post at online university

Scott Weber

Scott Weber, the nursing researcher accused of manipulating references and other publishing misconduct in at least seven retracted articles, has lost his position at Walden University, Retraction Watch has learned.

We noticed the other day that Weber’s name had disappeared from the Walden website and put in a call to the institution. A source there told us that Weber — a part-time faculty member who had been hoping for a full-time appointment at the school — apologized when confronted about the fraud.

The source, who did not want to be identified, said Continue reading Publishing scandal costs nursing researcher his post at online university

Publisher error handling two eye papers leads to retractions, new policy on notices

We can only imagine how Joe Hollyfield felt to learn from us, of all people, that his journal, Experimental Eye Research, had retracted two manuscripts in a recent issue.

The papers, “Mechanisms of retinal ganglion cell injury and defense in glaucoma,” by Qu J, Wang D, and Grosskreutz CL, and “Mitochondria: Their role in ganglion cell death and survival in primary open angle glaucoma,” by Osborne, NN, carried the same retraction notices:

This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy.

Because in our experience such unhelpful wording often masks interesting details — read, author misconduct — we called Hollyfield for comment. He graciously walked us through the retractions, explaining the case in detail, until we realized that we were talking about different papers entirely. Hollyfield, it turned out, thought we were asking about the travails of Sangiliyandi Gurunathan, an eye researcher from India whom we’d previously covered and whose work recently had been retracted by Experimental Eye Research and other journals for image manipulation.

But Hollyfield was unaware of the two retractions we’d intended to talk about with him and told us he’d look into them.

Here’s what he learned: Continue reading Publisher error handling two eye papers leads to retractions, new policy on notices

Anil Potti failed to disclose corporate ties in yet-to-be-retracted JAMA papers

Anil Potti, the former cancer researcher whose work has become the subject of intense scrutiny that has already led to the retraction of five papers, didn’t tell the Journal of the American Medical Association (JAMA) about two very relevant corporate relationships he had when he published papers there, Retraction Watch has learned.

JAMA has published two papers by Potti and colleagues: 2008’s “Gene Expression Signatures, Clinicopathological Features, and Individualized Therapy in Breast Cancer,” and 2010’s “Age- and Sex-Specific Genomic Profiles in Non-Small Cell Lung Cancer.”

The Cancer Letter, which has been way out front in the Potti case, first reported Potti’s relationships with Eli Lilly and CancerGuide Diagnostics (formerly Oncogenomics, Inc.). As The Chronicle, Duke’s student newspaper, reported last September, the two companies cut their ties with Potti in July 2010 after allegations of misconduct and lying about a Rhodes Scholarship came to light.

But that was after the two papers were published, and Potti had relationships with both since 2006. As The Chronicle notes, he was a director at CancerGuide Diagnostics (formerly Oncogenomics, Inc.), and Continue reading Anil Potti failed to disclose corporate ties in yet-to-be-retracted JAMA papers

Editor of Remote Sensing resigns over controversial climate paper; co-author stands by it

The editor of a journal that published a highly contentious article challenging claims of global warming has stepped down over the paper.

In a remarkable letter to his readership, Wolfgang Wagner, who until today was editor of Remote Sensing, an open-access journal that we’ve written about before, said he felt forced to resign because the review process at his journal — which, by implication, he shepherds — failed the scientific community (link added): Continue reading Editor of Remote Sensing resigns over controversial climate paper; co-author stands by it

A fifth retraction for Anil Potti, this one in Blood

courtesy Duke

The list of papers retracted by former Duke oncologist Anil Potti has grown to five. The notice, from Blood: Continue reading A fifth retraction for Anil Potti, this one in Blood

Ties that don’t bind: Group retracts parathyroid hormone crystallography paper

The authors of a 2008 paper alleging to have described how a particular protein binds to the parathyroid hormone have retracted it. The paper, “Structure of the Parathyroid Hormone Receptor C Terminus Bound to the G-Protein Dimer Gβ12,” has been cited 12 times, according to Thomson Scientific’s Web of Knowledge. According to the notice: Continue reading Ties that don’t bind: Group retracts parathyroid hormone crystallography paper

A quick Physical Review Letters retraction after author realizes analysis was “performed incorrectly”

One of the authors of a paper in Physical Review Letters has withdrawn it, after someone pointed out an error.

The paper, “Coulomb Forces on DNA Polymers in Charged Fluidic Nanoslits,” was written by Brown University’s Derek Stein and one of his graduate students, Yongqiang Ren. It was published in February of this year, and the retraction ran on July 20.

The notice is forthright: Continue reading A quick Physical Review Letters retraction after author realizes analysis was “performed incorrectly”

Cal Poly Pomona education researcher leaves post after rampant plagiarism is revealed

In late June, we wrote about a case of wholesale plagiarism involving an education researcher in California, Thienhuong N. Hoang. Our post prompted a flurry of emails from readers cluing us in to other cases in which Hoang, of California State Polytechnic University in Pomona, had lifted essentially entire articles from other scholars and changed little, if anything, but the author information.

For example, Hoang’s “‘The Contributions of Teachers’ Credentialing Routes and Experience Levels on Classroom Management,” in the January 2009 issue of the International Journal of Instruction, was the same, nearly word-for-word, as the work of two other authors, “Exploring the relationship between certification sources, experience levels, and classroom management orientations of classroom teachers,” published in Teaching and Teacher Education in 2007.

The International Journal of Instruction has removed the article from its archive and placed this announcement on its site: Continue reading Cal Poly Pomona education researcher leaves post after rampant plagiarism is revealed