Data artifact claims two fruit fly papers from leading UK group — who offer model response

jcbcoverA team of researchers led by Daniel St. Johnston, director of the Gurdon Institute at Cambridge and a prominent developmental biologist in the UK, has lost a pair of articles after finding that their data were unreliable. But rather than “correct” the record with subsequent papers, they’ve withdrawn the problematic work.

To our mind, this is a poster case of doing the right thing by science. We think the notices — as provided by the authors and reported by the journals — pretty much say it all, so we’ll let them speak for themselves, followed by some details St. Johnston shared with us.

The first article, “LKB1 and AMPK maintain epithelial cell polarity under energetic stress,” appeared in 2007 in the Journal of Cell Biology and has been cited 108 times, according to Thomson Scientific’s Web of Knowledge.

According to the retraction notice:

Continue reading Data artifact claims two fruit fly papers from leading UK group — who offer model response

Sir, that’s not my colon: Journal has a bite of a chicken and egg problem

Case report: An 85-year-old man eats some chicken and unknowingly swallows a bone. After two days of worsening abdominal pain, he shows up to the emergency room. A CT scan reveals the bone perforating his colon. He is rushed to surgery, which is successful. Then, during his otherwise uneventful recovery, he develops female breasts.

That’s not exactly the case report that showed up in the International Journal of Surgical Case Reports earlier this month, but then again, the images in the relevant case report aren’t exactly of someone’s colon, either.

With a warning that the clinical images below are mildly NSFW, here’s Figure 1 from the cleverly titled “Chicken or the leg: Sigmoid colon perforation by ingested poultry fibula proximal to an occult malignancy:” Continue reading Sir, that’s not my colon: Journal has a bite of a chicken and egg problem

Imperial clears Jatinder Ahluwalia of misconduct, blames “protracted negotiation” with Novartis for delay

logo_imperial_college_londonImperial College London has found that a former graduate student there — who had been found guilty of misconduct in two other institutions — did not commit fraud while at Imperial.

As first reported in the Times Higher Education today: Continue reading Imperial clears Jatinder Ahluwalia of misconduct, blames “protracted negotiation” with Novartis for delay

Retraction of JBC heparan paper shows much to like

jcb726coverWe have knocked the Journal of Biological Chemistry in the past for what we believed to be needless — and unhelpful — obfuscation. And more recently, we have praised the journal for taking what we believe to be positive steps in the direction of greater transparency.

Here, again, we come not to bury JBC but to praise it.

The journal has issued a retraction for a 2011 article by a group of researchers in London, England, led by Stephen Perkins. The paper, “The solution structure of heparan sulfate differs from that of heparin,” purported to show that:
Continue reading Retraction of JBC heparan paper shows much to like

Leading immunologist retracts paper that duplicated 2004 PNAS study

cellular immunologyUniversity of Glasgow professor Foo Yew “Eddy” Liew, a Fellow of the Royal Society, has retracted a paper in Cellular Immunology because it duplicated one of his earlier papers in the Proceedings of the National Academy of Sciences (PNAS).

Here’s the notice for “Expression and function of Toll-like receptor on T cells:”
Continue reading Leading immunologist retracts paper that duplicated 2004 PNAS study

Duplicate submission costs authors two papers on Parkinson’s disease

neuropeptidecoverA group of pharmacology researchers in the UK has lost two papers after submitting effectively identical versions to different journals — and getting them accepted, of course — just a day apart.

The first article appeared on the British Journal of Pharmacology‘s website on July 10, 2012. It was titled “Exendin-4 reverts behavioural and neurochemicaldysfunction in a pre-motor rodent model of Parkinson’s disease with noradrenergic deficit.”

Paper 2 appeared in the journal Neuropeptides in October, although it has an online pub date of August 24, and was titled “Exendin-4 reverses biochemical and behavioral deficits in a pre-motor rodent model of Parkinson’s disease with combined noradrenergic and serotonergic lesions.”

Continue reading Duplicate submission costs authors two papers on Parkinson’s disease

Not your data: Nursing paper retracted for misuse of findings

nurse education todayWe’re all for research on improving communication and collaboration among colleagues. But we trust that the experts know what they’re doing. You can see where this is going.

The journal Nurse Education Today has retracted a 2012 article, “Interprofessional learning in acute care: Developing a theoretical framework,” by a UK scholar because, how shall we put it, he might need a few lessons in interprofessionalism.

The retraction notice explains it neatly: Continue reading Not your data: Nursing paper retracted for misuse of findings

Cossu-UCL follow-up: PLOS ONE paper to be corrected

Cossu
Cossu

We have a follow-up from last week’s story about a University College London (UCL) investigation into the work of Giulio Cossu that found errors but no “deliberate intention to mislead.”UCL said it will not make the full report available: Continue reading Cossu-UCL follow-up: PLOS ONE paper to be corrected

UCL finds errors in work by biologist Cossu, but no “deliberate intention to mislead”

cossu
Cossu

A cell biologist at University College London (UCL) who has had one paper retracted and another corrected has been cleared of misconduct by the university.

The news, first reported by Times Higher Education, comes after a retraction of a paper by Giulio Cossu prompted by pseudonymous whistleblower Clare Francis that we wrote about in January.

Here’s the full text of UCL’s statement on the investigation: Continue reading UCL finds errors in work by biologist Cossu, but no “deliberate intention to mislead”

A new record? 27-plus years later, a notice of redundant publication

royal society bA 1984 paper in Philosophical Transactions of The Royal Society B is now subject to a notice of redundant publication because a lot of it had been published in Cell the same year.

Whether 28 years — 27 years and 9 months, to be precise — is any kind of official record is unclear, since we haven’t really kept track of notices of redundant publication. It would, however, beat the record for longest time between publication and retraction, 27 years and one month.

Here’s the notice, which ran in September of last year but just came to our attention: Continue reading A new record? 27-plus years later, a notice of redundant publication