PNAS paper on dengue virus pulled due to contamination

PNAS_ak11smThe authors of a paper on dengue virus vaccine design published last year in PNAS are retracting it after discovering that their experimental dengue virus was contaminated.

Although they are confident that the strategy is sound, the authors write in their commendably detailed retraction notice that the “inadvertent error” rendered the results “uninterpretable.”

Here’s the retraction notice: Continue reading PNAS paper on dengue virus pulled due to contamination

Double-dipping equals double retraction for fracking paper

tran por medTransport in Porous Media and the Journal of Petroleum Science and Engineering have retracted two articles on shale gas by Chinese researchers for duplication and other “mistakes.”

The articles came from a group at the State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation at Southwest Petroleum University, in Chengdu. The articles share a corresponding author.

According to the abstract of the TPM paper, “Pressure Transient Analysis for Multi-stage Fractured Horizontal Wells in Shale Gas Reservoirs”:

The presented model could be used to interpret pressure signals more accurately for shale gas reservoirs.

Make that a double, according to its notice:

Continue reading Double-dipping equals double retraction for fracking paper

NIH cancer paper retracted for faked data

JCIFollowing an investigation into research misconduct, the Journal of Clinical Investigation has retracted a cancer genetics paper from a laboratory at the National Institutes of Health due to “data falsification and fabrication” of four figures and a table in the paper.

The paper, “FOXO3 programs tumor-associated DCs to become tolerogenic in human and murine prostate cancer,” describes an overexpressed gene in mouse prostate cancers that appears to suppress immune system cells.

The journal retracted the paper following an investigation into author Stephanie K. Watkins, then a postdoctoral fellow at the National Cancer Institute. According to a NIH press release released about the study in March 2011, the work “has led to the submission of a patent application by the NIH on behalf of Hurwitz and Watkins to target FOXO3 as a way to boost immune responses in cancer and to silence excessive immune responses in autoimmune diseases.” We found an NIH record of the patent application, but no record of an approved patent at the United States Patent and Trademark Office under either Hurwitz or Watkins’ names.

The paper has been cited 62 times, according to Thomson Scientific’s Web of Knowledge. Here’s the full notice: Continue reading NIH cancer paper retracted for faked data

Undisclosed industry funding prompts correction of fracking paper

152 page minimum spine. Editor: Matt Hotze, JEM: Esther RTP:  Diane Murphy

Environmental Science & Technology has issued a correction for a March 2015 paper on methane contamination from gas wells after learning that the authors failed to disclose funding from Chesapeake Energy Corp., a major U.S. energy producer.

The paper, “Methane Concentrations in Water Wells Unrelated to Proximity to Existing Oil and Gas Wells in Northeastern Pennsylvania,” came from a group led by Donald Siegel, of Syracuse University. In the correction, Siegel acknowledges having received “funding privately” from Chesapeake for the study, which found: Continue reading Undisclosed industry funding prompts correction of fracking paper

Lead poisoning article disappears for “legal” — but mysterious — reasons

OM_ak4A 2014 article in Occupational Medicine has been pulled with no retraction notice. Instead, the text was replaced with eight ominous words:

This article has been removed for legal reasons

Continue reading Lead poisoning article disappears for “legal” — but mysterious — reasons

CrossFit gym owner sues Ohio State, says fraudulent data led to $273 million in NIH grants

Mitch Potterf
Mitch Potterf
In an lawsuit unsealed yesterday, the owner of a CrossFit gym is suing Ohio State University (OSU) under the False Claims Act, claiming that researchers faked data in a university-based study involving his gym — and that OSU used the study to win $273 million in Federal grants.

The suit, originally filed in February in the U.S. District Court of Southern Ohio by Mitch Potterf, owner of a Columbus, Ohio CrossFit, alleges that a 2013 paper by OSU’s Steven Devor and colleagues falsely reported that nine subjects had dropped out of the study because of “overuse or injury.” The study, we should note, concluded that CrossFit is a useful form of exercise. It has been cited twice, according to Thomson Scientific’s Web of Knowledge.

As John Thomas, an attorney who handles False Claims Act cases, explained in a Retraction Watch guest post in March: Continue reading CrossFit gym owner sues Ohio State, says fraudulent data led to $273 million in NIH grants

Highly cited cancer researcher pulls review for “similar text and illustrations”

AbdomImaging_ak8The author of a 2006 review article published in Abdominal Imaging has retracted it because it hews too closely to previously published articles.

The review described the latest imaging techniques used in cancer, focusing on genitourinary conditions.

Here’s the full text of the retraction notice for “New Horizons in Genitourinary Oncologic Imaging”:

Continue reading Highly cited cancer researcher pulls review for “similar text and illustrations”

Drunk rats paper wasted by “significant statistical errors”, among other issues

MolBiolRep_ak5Authors from Xinxiang Medical University in Weihui, China, are retracting a 2014 paper in Molecular Biology Reports because… well, because lots of things.

The researchers exposed nine rats to acute levels of alcohol then compared them to unexposed mice rats, noting differences in gene expression and molecular pathways.

But no one is toasting these findings anymore. Here are the details behind the retraction, courtesy of the notice:

Continue reading Drunk rats paper wasted by “significant statistical errors”, among other issues

Third structure slip-up for chemist in Korea yields retraction

Chem_ak3Authors of a 2010 Chemistry – A European Journal article have retracted it “due to the wrong assignment of structure” of catalysts.

The retraction is the third, by our count, for corresponding author Doo Ok Jang, a chemist at Yonsei University in Wonju. Jang authored one of the previously retracted papers with Sung Jun Kim and the other with Sang Yoon Kim. Both papers were also sunk by misassigned structures.

The current study, “Enantioselective Radical Addition to Ketimines: A Synthetic Route Towards α,α-Disubstituted α-Amino Acids,” is authored by all three chemists. Here’s the retraction notice:

Continue reading Third structure slip-up for chemist in Korea yields retraction

So you want to be a whistleblower? Part II

john thomas
John R. Thomas

This is the second article in a series by John R. Thomas, Jr., a lawyer at Gentry Locke [Editor’s note, 3/26/19: He has since moved to Haley, Hafemann, Magee and Thomas] who represents whistleblowers in a variety of False Claims Act cases. In this installment, he writes about how whistleblowers can tell if they have a viable FCA case.

In my first article, I briefly outlined the role that the False Claims Act (FCA) can play in promoting scientific integrity and safeguarding public grant funding. This article will answer a more substantive and practical question that a potential whistleblower must consider: What constitutes a viable FCA case? Continue reading So you want to be a whistleblower? Part II