STAP stem cell researcher Obokata loses another paper

Nature protocols

The first author of two high-profile Nature retractions about a technique to easily create stem cells has lost another paper in Nature Protocols.

Haruko Obokata, once “a lab director’s dream,” according to The New Yorker, also had her PhD revoked from Waseda University last fall.

After learning of concerns that two figures are “very similar” and “some of the error bars look unevenly positioned,” the rest of the authors were unable to locate the raw data, according to the note. The journal could not reach Obokata for comment before publishing the retraction.

Reproducible subcutaneous transplantation of cell sheets into recipient mice” has been cited 21 times, according to Thomson Reuters Web of Science. It was published in June 2011, soon after Obokata earned her PhD. 

Here’s the note:

Continue reading STAP stem cell researcher Obokata loses another paper

2001 sepsis paper “deviates from the ethical standard of authorship,” says journal

Screen Shot 2016-02-11 at 1.50.33 PMWe don’t have a lot of information on a recent retraction of a 2001 paper published in a Japanese journal — just a brief and strongly worded note explaining that it follows “a strict, extensive, and judicious review.”

The paper, retracted 14 years after it was published, describes patients in Okinawa, Japan who developed severe symptoms following infection by bacteria belonging to the Aeromonas genus. One example:

The one patient was a 15-year-old high school girl student, who had been healthy in her school life, was admitted to the hospital with a sudden onset of left thigh muscle pain and swelling. She subsequently went into septic shock and died one day after admission. Pathological examination on autopsy revealed massive gas formation, skin bullas and ulcers, and extensive severe soft tissue damage throughout the body.

Aeromonas species infection with severe clinical manifestation in Okinawa, Japan-association with gas gangrene” has been cited three times, according to Thomson Scientific’s Web of Knowledge. It was published in a Japanese journal, Rinsho Biseibutshu Jinsoku Shindan Kenkyukai Shi — which translates to the Journal of the Association for Rapid Method and Automation in Microbiology.

The retraction note suggests that there are major flaws:  Continue reading 2001 sepsis paper “deviates from the ethical standard of authorship,” says journal

Journals retracts three bone papers for duplication by same author

1-s2.0-S0168365907X02700-cov150hA journal is Journals are retracting three papers after a biomaterials researcher duplicated his own work, sometimes using the same figures to describe different experiments.

Two of the papers are on bone regeneration; one is about targeting tumors. In addition to issues with figures, two one of the retraction notes explain that the papers contain “widespread plagiarism of text” from other papers by the researcher, Hossein Hosseinkhani.

Hosseinkhani is currently affiliated with the National Taiwan University of Science and Technology; when he did the work in the now retracted papers, published in 2004 and 2007, he was based at Kyoto University Hospital and then National Institute for Materials Science in Japan.

The Journal of Controlled Release published all three two of the papers. Here’s the retraction note for “Bone regeneration through controlled release of bone morphogenetic protein-2 from 3-D tissue engineered nano-scaffold,” which has been cited 118 times, according to Thomson Scientific’s Web of Knowledge.

Continue reading Journals retracts three bone papers for duplication by same author

2001 Fujii papers retracted — finally. What took so long?

BJO

Nearly four years after an analysis of more than 160 papers by Yoshitaka Fujii concluded the chances the data were authentic were infinitesimally small, the British Journal of Ophthalmology has decided to formally retract one of the papers included in that review.

The name Yoshitaka Fujii should ring a bell — an alarm bell, in fact — for our readers. He’s firmly listed in the number one spot on our leaderboard, with more than 180 retractions.

The recently retracted paper — “Ramosetron compared with granisetron for the prevention of vomiting following strabismus surgery in children” — has been included in that retraction total for years, because it was part of a seminal 2012 analysis by J.B. Carlisle that put the odds of data occurring naturally in some of Fujii’s papers at: Continue reading 2001 Fujii papers retracted — finally. What took so long?

Retractions follow misconduct by biologist, one more on the way

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Two journals have retracted papers by a biologist at the University of Tokyo who admitted to scientific misconduct, including data duplication and misrepresentation. Another journal is planning to retract one of the researcher’s papers later this month.

Hyun Kim studies a protein known as the “ski protein.” However, one analysis of the role of ski protein in development was retracted late last month by the Asian-Australasian Journal of Animal Sciences. The journal decided to investigate after Kim admitted to misconduct in two other papers published in a different journal.

Here’s the note for the paper:

Continue reading Retractions follow misconduct by biologist, one more on the way

Osteoporosis paper felled by concerns with “scientific integrity”

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A paper suggesting that exposure to sunlight might help prevent hip fractures in the elderly has been retracted, due to duplication and “concerns about the underlying data.”

An expression of concern that appeared last July flagged the 2005 paper as containing text that matched another paper with the same first author that was published in 2011. According to the publisher, that duplicated text sparked a closer look at the text, which raised concerns about the scientific integrity of the paper.

The retraction note, published by the Journal of Bone and Mineral Research, says that the first author was responsible for the content of the paper: Continue reading Osteoporosis paper felled by concerns with “scientific integrity”

When a paper is retracted, so is its previous correction–sometimes

1-s2.0-S0968089612X0018X-cov150hSometimes, the path to correcting the scientific record takes a few turns. In the case of a paper about a new cancer compound, authorship issues led to a correction and, ultimately, a retraction — along with a double-back to retract the earlier correction.

We reported on the first part of the story back in January: A 2011 paper that described a novel compound that could work as a drug for the side effects of chemotherapy was corrected in 2012 to add additional authors. But once the authors realized their supposedly novel compound had actually been synthesized by another author, they decided to retract the paper from Bioorganic and Medicinal Chemistry earlier this year, concluding “these facts made the paper inappropriate and unfaithful.”

Apparently, around the same time, the authors decided to retract the earlier correction, as well:

Continue reading When a paper is retracted, so is its previous correction–sometimes

University revokes PhD of first author on retracted STAP stem cell papers

800px-Waseda_University_Logo.svgWaseda University has revoked the doctorate degree of the first author on the now-retracted Nature papers about a technique to create stem cells.

The technique — which claimed to provide a new way to nudge young cells from mice into pluripotency — was initially described in two 2014 Nature papers, both first-authored by Haruko Obokata. However, the papers were soon mired in controversy, corrected, then retracted later that year due to “several critical errors,” some of which were categorized by a RIKEN investigation as misconduct.

Shortly after Nature retracted the two papers, Waseda revoked Obokata’s doctorate degree — on a probationary basis, according to the university: Continue reading University revokes PhD of first author on retracted STAP stem cell papers

“Insufficient permission” from funder resects liver disease paper

HepatologyA study on chronic liver inflammation was pulled from the journal Hepatology because of “insufficient permission by the authors’ funding institution to submit and publish the manuscript.” 

The paper, which was published in July, looked into how steatosis, the abnormal retention of fat in the liver, turns into steatohepatitis, also known as fatty liver disease. Researchers found that Treg cells play a central role in controlling the disease.

Unfortunately, the journal’s managing editor didn’t provide any information about the nature of the permission problems, and the notice doesn’t give any details.

Here it isin full:

Continue reading “Insufficient permission” from funder resects liver disease paper

Mirror image in plant study flagged on PubPeer grows into retraction

djs_mpmi_28_9_cover-online.inddA 2010 paper on plant fungus has been retracted after a comment on PubPeer revealed that a study image had been flipped over and reused to represent two different treatments.

In May, a commenter pointed out the plants in Figure 2a of the paper in the journal Molecular Plant-Microbe Interactions “look remarkably similar.” A commenter writing under the name of corresponding author, Yukio Tosa at Kobe University in Japan, posted a response two days later agreeing with the assessment and stating that the paper should be retracted.

The notice reads: Continue reading Mirror image in plant study flagged on PubPeer grows into retraction