Category: germany retractions

Unglaublich! Boldt investigation may lead to more than 90 retractions

Ludwigshafen Hospital, via Wikimedia http://commons.wikimedia.org/wiki/File:Klinikum_Ludwigshafen_Nordseite.jpg

Self-plagiarism alert: A very similar version of this post is being published online in Anesthesiology News, where one of us (AM) is managing editor.

Unglaublich is the German word for unbelievable, and it’s an apt description for the latest development in the case of Joachim Boldt.

Boldt, a prominent German anesthesiologist, has been at the center of a research and publishing investigation since last October, when the journal Anesthesia & Analgesia retracted a 2009 article of his over concerns of data manipulation. This morning, the German medical board overseeing the case, the Landesärztekammer Rheinland-Pfalz (LÄK-RLP),  released its findings — and they are truly stunning.

According to LAK, somewhere in the neighborhood of 90 of Boldt’s published articles might require retraction because the investigator failed to obtain approval from an institutional review board to conduct the research.

We don’t read German. But, fortunately, the LÄK-RLP announcement was accompanied by a joint letter posted to the websites of 11 major anesthesia journals. We do read English, and here’s what that letter says: Continue reading Unglaublich! Boldt investigation may lead to more than 90 retractions

Three more Bulfone-Paus retraction notices out, in Journal of Immunology

Silvia Bulfone-Paus

The retraction notices for papers by Silvia Bulfone-Paus continue to appear. Yesterday, the Journal of Immunology posted notices for these three previously accepted retractions by the researcher, work at whose Borstel Centre lab is under investigation for misconduct.

In retraction notice, Bulfone-Paus “declares” data and conclusions confirmed; journals accept six more retractions

Silvia Bulfone-Paus

There was more news today about papers co-authored by Silvia Bulfone-Paus, whose lab at Research Centre Borstel has been under investigation for scientific misconduct.

The EMBO Journal, which we reported last month had accepted the retraction of a 2005 Bulfone-Paus paper that has been cited 37 times, published the retraction notice for the study today:

Eight of the authors (ZO, LT, UM, PB, CB, DA, RP and SB-P) wish to retract this paper, following an independent formal investigation initiated by the Research Center Borstel into scientific misconduct (see http://www.fz-borstel.de/cms/index.php?id=1). The investigation concluded that multiple figures contained PCR and western blot duplications and possible other manipulations (Figures 2A, 3A, 4A, 5, 7A and 7C, Supplementary Figures S1A, S2A and S2B, unconfirmed: Figure 1C). The above signed declare that Vadim Budagian and Elena Bulanova conducted these experiments and generated the figures. The authors declare that key experiments presented in the majority of these figures were recently reproduced and that the results confirmed the experimental data and the conclusions drawn from them. However, due to these unacceptable irregularities, the listed authors retract this paper in its entirety and regret any adverse consequences that may have resulted from its publication. Vadim Budagian and Elena Bulanova declined to sign the retraction.

As retraction notices go, this is better than average, we must say. It’s certainly better than the many opaque notices we’ve seen. But there’s a line in there that Karin Wiebauer and David Hardman, both of whom brought the notice to our attention, found curious: Continue reading In retraction notice, Bulfone-Paus “declares” data and conclusions confirmed; journals accept six more retractions

Sixth Bulfone-Paus retraction accepted

Silvia Bulfone-Paus

A journal has accepted the sixth retraction of a paper co-authored by Silvia Bulfone-Paus, the Research Centre Borstel announced late last week. Borstel has been investigating allegations that two of Bulfone-Paus’s former postdocs manipulated images.

The paper, in the Scandinavian Journal of Immunology, is titled Continue reading Sixth Bulfone-Paus retraction accepted

Four more Bulfone-Paus paper retractions accepted

About two weeks ago, we reported on the first retraction of a paper co-authored by Silvia Bulfone-Paus, whose work at her Research Center Borstel lab is being investigated for misconduct. On Friday, Borstel announced that journals had accepted four more retractions of papers by Bulfone-Paus’s group.

Three of those papers are in the Journal of Immunology (citations according to Thomson Scientific’s Web of Knowledge): Continue reading Four more Bulfone-Paus paper retractions accepted

Paper by Silvia Bulfone-Paus to be retracted

At least one of the dominoes may be falling from a scandal at Research Center Borstel.

Retraction Watch has learned that one of six papers that an investigation found to include data manipulation will be retracted by the Journal of Leukocyte Biology. The paper, “ATP induces P2X7 receptor-independent cytokine and chemokine expression through P2X1 and P2X3 receptors in murine mast cells,” includes Silvia Bulfone-Paus as a co-author. The retraction notice will appear in the March issue of the journal, editor Luis Montaner told Retraction Watch today.

Bulfone-Paus is at the center of a complex case, and we’ll refer you to Nature‘s excellent coverage. As Nature reported last month: Continue reading Paper by Silvia Bulfone-Paus to be retracted

Authors plan to appeal Global Ecology and Biogeography retraction

The authors of a Global Ecology and Biogeography study originally published in November 2009 and retracted last week are appealing the decision with the Committee on Publication Ethics (COPE), Retraction Watch has learned. Continue reading Authors plan to appeal Global Ecology and Biogeography retraction

Boldt under investigation for drug trial death

As we’ve previously reported, German anesthesiologist Joachim Boldt has been under investigation for apparent misdeeds — including lack of proper informed consent and possible data fabrication — that led to the retraction earlier this year of an article in Anesthesia & Analgesia. We’ve just learned that Boldt also has drawn scrutiny from German prosecutors for his role in a clinical trial earlier in the decade that led to the death of one patient and the near-death of another.

According to an article in the Weinheimer Nachrichten, that incident occurred when Boldt was at the University Hospital Giessen. Officials there told us there was an investigation into the matter but declined to comment further.

Here’s Google’s translation of the Weinheimer Nachrichten piece: Continue reading Boldt under investigation for drug trial death

Update on the Gressner case: Son Olav says he’s the unfairly targeted “bête noire”

We have an update on the case of Olav and Axel Gressner, a father-son (or, in this case, son-father) pair of German liver researchers caught up in a fraud investigation. The inquiry focused on Olav, who left the University of Aachen under a cloud of suspicion. A 2008 research letter on which he was a co-author (his father was senior author) was retracted earlier this year by the Journal of Hepatology.

The journal’s position in the retraction notice,  published online in June and in print in September, bears repeating here. The authors: Continue reading Update on the Gressner case: Son Olav says he’s the unfairly targeted “bête noire”

After misrepresentation allegations, German anesthesiologist Joachim Boldt out as hospital’s chief physician

Ludwigshafen Hospital, via Wikimedia http://commons.wikimedia.org/wiki/File:Klinikum_Ludwigshafen_Nordseite.jpg

Joachim Boldt, a leading German anesthesiologist who had a 2009 paper in Anesthesia & Analgesia retracted last month* amid allegations  that he had misrepresented parts of the study, has been relieved of his duties as chief physician at Ludwigshafen Hospital.

A press release from the German Society for Anesthesiology and Intensive Care Medicine (DGAI) condemns Boldt’s actions. The press release goes on (translated from German): Continue reading After misrepresentation allegations, German anesthesiologist Joachim Boldt out as hospital’s chief physician