The HeLa problem: What a retraction says about whether cancer researchers can trust their cell lines

Retraction Watch readers who’ve read Rebecca Skloot’s bestseller The Immortal Life of Henrietta Lacks may remember that decades ago, scientists began realizing that Lacks’s cells, now known as the HeLa cell line and used in labs around the world, were so good at proliferating that they had taken over many other cell lines researchers use to study human disease.

Such readers would have been nodding their heads at a front-page Wall Street Journal on Saturday. As Amy Dockser Marcus (no relation to Adam) reports: Continue reading The HeLa problem: What a retraction says about whether cancer researchers can trust their cell lines

Not so fast! Journal retracts paper from Boldt group over author hijinks, more

We knew we hadn’t heard the last of Joachim Boldt, whose nearly 90 retractions make him the putative record holder for a single author in this indistinguished club. But we didn’t expect this:

The European Journal of Anaesthesiology has retracted a paper, “Supplemental oxygen reduces serotonin levels in plasma and platelets during colorectal surgery and reduces postoperative nausea and vomiting,” from Boldt’s former colleagues at the Klinikum Ludwigshafen after determining that the authors were trying to hide their association with the disgraced anesthesiologist.

Continue reading Not so fast! Journal retracts paper from Boldt group over author hijinks, more

Bulfone-Paus retraction count grows to 13 with one in Transplantation

Silvia Bulfone-Paus, the Borstel Institute researcher who was forced to step down as institute director and has already retracted 12 papers, has retracted another, this one in Transplantation. Here’s the text of the notice: Continue reading Bulfone-Paus retraction count grows to 13 with one in Transplantation

Ghost authorship? Two Meccanica retractions as an author’s work is plagiarized by disappearing scientists

About two years ago, Marc Duflot, a research engineer at Cenaero, heard a disturbing tale from a collaborator. The collaborator, it seemed, had been asked to review a paper submitted to a journal, and noticed that it was remarkably similar to a paper by Duflot. Duflot’s collaborator recommended that the journal reject the paper, and it did. Duflot tells Retraction Watch (we added a link to the paper in question):

Then, several months later, I discovered that the…paper had been submitted and accepted in Meccanica. If I remember correctly, I discovered it by searching the web with Google Scholar with terms related to my field of expertise.

So in January 2010, Duflot wrote to the editors of Meccanica to alert them to the plagiarism by the authors, M. Garzon and D. Sargoso of the University of Madrid. He concluded his email:

I am deeply disappointed by the fraudulent behaviour of M. Garzon and D. Sargoso. Strangely, I cannot find any mention of these two people on the web neither of the Department of Civil Engineering at the University of Madrid. Otherwise, I would have reported this to the head of their department.

An editorial assistant got back to him: Continue reading Ghost authorship? Two Meccanica retractions as an author’s work is plagiarized by disappearing scientists

Expression of Concern for a Bulfone-Paus paper

Retraction Watch readers may recall the story of Silvia Bulfone-Paus, who has been forced to retract 12 papers and has another under review at Blood. All of that scrutiny came after an investigation by her home institution, Germany’s Borstel Institute, that found evidence of image manipulation.

The latest development is perhaps no surprise. It concerns a review Bulfone-Paus and her colleagues published in BioEssays in 2006. Here’s the Expression of Concern, which was published online in July but just came our attention (we’ve added links to our coverage of specific retractions): Continue reading Expression of Concern for a Bulfone-Paus paper

You can do that? A massive correction in Nature, but no retraction

courtesy Nature

This past April, Amparo Acker-Palmer and colleagues published a study in Nature, “Ephrin Bs are essential components of the Reelin pathway to regulate neuronal migration.” Within a day of its publication, Nature readers were raising questions about many of its figures. They started like this:

Andy Gu said:

Looks like Fig 1a, the two middle figures are actually the same with little move from desired regions. I don’t trust their data now…..

After several such comments, Nature senior editor Noah Gray weighed in: Continue reading You can do that? A massive correction in Nature, but no retraction

*Savaskan and Nitsch, forced to retract FASEB J paper, correct Cell study with duplicated figure

In August, we wrote about the complicated case of a paper retracted from FASEB Journal that had originally been slated for a correction instead. There had been allegations of misconduct by one of the authors, Nicolai E. Savaskan, and the key parts of the retraction notice for the paper were as follows:

A well-recognized and top-class fact finding commission concluded that the publication contains gross flaws. A key figure (Figure 14) and the conclusions drawn from it could not be underlined with the corresponding primary data.

Savaskan told us at the time that FASEB Journal had agreed to a correction of the figure in question, but ended up retracting the paper after receiving a letter from Annette Gruters-Kieslich at Charite – Universitatsmedizin Berlin, where the work was done. We didn’t get much of an answer from FASEB Journal about why they changed their minds.

*Since understanding why one paper warrants a correction and another gets retracted is important for us at Retraction Watch, a correction of a 2009 Cell paper by a group that included Savaskan and his FASEB J c0-author Robert Nitsch caught our eye. The correction for “Synaptic PRG-1 Modulates Excitatory Transmission via Lipid Phosphate-Mediated Signaling” — a paper cited nine times so far, according to Thomson Scientific’s Web of Knowledge — ran in the September 16, 2011 issue of Cell: Continue reading *Savaskan and Nitsch, forced to retract FASEB J paper, correct Cell study with duplicated figure

Duplicate submission from 2002 in American Journal of Psychiatry earns an Expression of Concern

The American Journal of Psychiatry has issued an Expression of Concern about a 2003 paper that was apparently simultaneously submitted to a German-language journal. According to the notice in the August 2011 issue of the journal (link added): Continue reading Duplicate submission from 2002 in American Journal of Psychiatry earns an Expression of Concern

Following investigation, FASEB Journal retracts paper after agreeing to run a correction

A contested retraction has punctuated the complicated saga of a 2003 paper in the FASEB Journal. (FASEB stands for the Federation of American Societies for Experimental Biology.)

A retraction notice for the paper, “Molecular analysis of Nogo expression in the hippocampus during development and following lesion and seizure,” appeared in mid-June: Continue reading Following investigation, FASEB Journal retracts paper after agreeing to run a correction

University investigating leading German derm lab that retracted Immunology paper

The laboratory of Michael Hertl, a German dermatology researcher with an international reputation, is under investigation for possible misconduct, according to a legal official at Hertl’s institution, Philipps-Universitat Marburg.

The acknowledgement was prompted by our query earlier this week about a 2008 paper from Hertl’s group that had been retracted by the journal Immunology. According to the July 25 retraction notice: Continue reading University investigating leading German derm lab that retracted Immunology paper