Critics of Poldermans’ work baffled by NEJM stance on DECREASE papers

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Don Poldermans

A pair of researchers who have been calling for the retraction of two papers by cardiology researcher Don Poldermans say the New England Journal of Medicine is  “not justified” “disappointing” in its refusal to pull the articles.

A little background: Poldermans resigned from Erasmus University in 2011 after having been accused of misconduct. Last week, we reported that the European Heart Journal had issued an expression of concern for a 2001 article on which he was first author.

The New England Journal of Medicine added editor’s notes to two of Poldermans’ articles. But as Larry Husten at Forbes reports, the journal has no intention of retracting the papers: Continue reading Critics of Poldermans’ work baffled by NEJM stance on DECREASE papers

“Wide differences in the memories” prompt expression of concern for Poldermans paper

EHJThe European Heart Journal has issued an expression of concern for a 2014 2001 paper by Don Poldermans, the Dutch heart researcher who stepped down from his post at Erasmus University after being accused of misconduct.

The article, “Bisoprolol reduces cardiac death and myocardial infarction in high-risk patients as long as 2 years after successful major vascular surgery,” appeared in July and reported data from the DECREASE trial. Poldermans, who left Erasmus in 2011, has acknowledged failing to receive informed consent from some patients in one phase of the DECREASE study but denied having fabricated results.

According to the notice: Continue reading “Wide differences in the memories” prompt expression of concern for Poldermans paper

Scientist threatening to sue PubPeer claims he lost a job offer because of comments

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Fazlul Sarkar, via Wayne State

Last month, PubPeer announced that a scientist had threatened to sue the site for defamation. At the time, all PubPeer would say was that the “prospective plaintiff” is a US researcher” who was “aggrieved at the treatment his papers are getting on our site.”

Today, PubPeer revealed the that the prospective plaintiff was Fazlul Sarkar, a distinguished professor of pathology at Wayne State University in Detroit. Sarkar’s attorney, Nicholas Roumel, tells us that Sarkar had a job offer from the University of Mississippi, which rescinded it after seeing comments about his work on PubPeer.

We asked to see the letter rescinding the offer, but Roumel said he couldn’t send it because he and Sarkar are “in the process of making a claim against them.”

We also asked if there was an investigation into Sarkar’s work. Roumel told us:

As for any investigation, federal regulations make such things strictly confidential, so I can’t comment either way.

According to a post on PubPeer: Continue reading Scientist threatening to sue PubPeer claims he lost a job offer because of comments

Researcher who broke into lab up to nine retractions

bichaw_v053i036.inddKarel Bezouška, a researcher who broke into a lab refrigerator to tamper with an investigation into his work, has nine retractions.

Here’s the retraction notice in Biochemistry for 2010’s “Cooperation between Subunits Is Essential for High-Affinity Binding of N-Acetyl-d-hexosamines to Dimeric Soluble and Dimeric Cellular Forms of Human CD69:” Continue reading Researcher who broke into lab up to nine retractions

Former UT-Southwestern cancer researchers faked data in 10 papers: ORI

ut southwesternThe Office of Research Integrity (ORI) has ruled in a case we’ve been following for nearly two years — and which seems to have been launched after Retraction Watch readers took a careful look at figures from what appeared to be an unrelated case.

Takao Takahashi and Makato Suzuki, both former postdocs at a cancer research center at UT-Southwestern, both “knowingly, intentionally, and recklessly falsified data” in a total of 10 papers, according to the ORI. Takahashi, now at Gifu University in Japan, was responsible for fakery in four papers, while Suzuki, now at Kumamoto University Hospital, also in Japan, falsified data in six.

We reported on the retraction of the four Takahashi papers, and one of the Suzuki papers, in November 2012. At that time, Adi Gazdar, the head of the lab where the researchers worked, told us that
Continue reading Former UT-Southwestern cancer researchers faked data in 10 papers: ORI

Another retraction for Diederik Stapel, this one from Dutch drama festival on “truth and reality”

stapel_npcHere’s a case of art imitating science.

The organizers of a Dutch drama festival have put a halt to a play about the disgraced social psychologist Diederik Stapel, prompting protests from the authors of the skit — one of whom is Stapel himself.

According to an article in NRC Handelsblad: Continue reading Another retraction for Diederik Stapel, this one from Dutch drama festival on “truth and reality”

“Potentially groundbreaking,” “highly provocative:” Nature STAP stem cell peer reviews published

nature 73014A day after we published the cover letter and peer review reports about the STAP stem cell paper rejected by Science, Science‘s news section has published the same material for the version rejected by Nature.

From Science‘s news story about the document: Continue reading “Potentially groundbreaking,” “highly provocative:” Nature STAP stem cell peer reviews published

“Truly extraordinary,” “simply not credible,” “suspiciously sharp:” A STAP stem cell peer review report revealed

science 62714Retraction Watch readers are of course familiar with the STAP stem cell saga, which was punctuated by tragedy last month when one of the authors of the two now-retracted papers in Nature committed suicide.

In June, Science‘s news section reported:

Sources in the scientific community confirm that early versions of the STAP work were rejected by Science, Cell, and Nature.

Parts of those reviews reviews have surfaced, notably in a RIKEN report. Science‘s news section reported:

For the Cell submission, there were concerns about methodology and the lack of supporting evidence for the extraordinary claims, says [stem cell scientist Hans] Schöler, who reviewed the paper and, as is standard practice at Cell, saw the comments of other reviewers for the journal. At Science, according to the 8 May RIKEN investigative committee’s report, one reviewer spotted the problem with lanes being improperly spliced into gel images. “This figure has been reconstructed,” the RIKEN report quotes from the feedback provided by a Science reviewer. The committee writes that the “lane 3” mentioned by the Science reviewer is probably the lane 3 shown in Figure 1i in the Nature article. The investigative committee report says [co-author Haruko] Obokata told the committee that she did not carefully consider the comments of the Science reviewer.

The entire reports, however, have not been made available. Retraction Watch has obtained the full text of the editor’s cover letter and reviews of the rejected Science paper. The reviews are full of significant questions and doubts about the work, as would be expected in a rejection. We present them here, to fill in some of the gaps and help readers consider how the research eventually made it through peer review: Continue reading “Truly extraordinary,” “simply not credible,” “suspiciously sharp:” A STAP stem cell peer review report revealed

Diabetes researcher Cory Toth now up to nine retractions

neuroscienceCory Toth is up to nine retractions.

The University of Calgary researcher who told us earlier this year that he “will not be publishing in the world of science in the future” has retracted two papers from Neuroscience.

Here’s the notice for “Local erythropoietin signaling enhances regeneration in peripheral axons:” Continue reading Diabetes researcher Cory Toth now up to nine retractions

Danish committee rejects much of Klarlund Pedersen’s appeal of misconduct findings

Klarlund Pedersen
Klarlund Pedersen

The Danish Committees on Scientific Dishonesty (DCSD, Danish acronym UVVU) has partially reversed a December 2013 finding of misconduct against a scientist in Denmark, but has upheld most of its ruling.

Bente Klarlund Pedersen, whose case was tied up with that of Milena Penkowa, another scientist in Denmark found guilty of misconduct, committed misconduct in four of 12 articles examined, not six, the DCSD said in a statement last week.

Here’s the English summary (the DCSD does not name scientists under investigation publicly, but Pedersen has confirmed this is about her): Continue reading Danish committee rejects much of Klarlund Pedersen’s appeal of misconduct findings