Category: basic life sciences retractions

Science Signaling corrects data fudged by former UCSF student

afbb251f8bc8f71e26b313c77669d48fA paper containing data fudged by former University of California San Francisco grad student Peter Littlefield has been corrected. We knew that this was coming — last month, the Office of Research Integrity issued a report that Littlefield had admitted to misconduct, and agreed to a retraction or correction of the two affected papers.

Published in Science Signaling, “Structural analysis of the /HER3 heterodimer reveals the molecular basis for activating HER3 mutations” examined the structural details of a protein associated with cancer. It has been cited two times, according to Thomson Scientific’s Web of Knowledge.

According to the correction note, the concentration of a protein presented in one figure was “miscalculated;” in another figure, the error bars were “calculated incorrectly.”

A statement from the UCSF affirmed that principle investigator Natalie Jura has “not been implicated in any research misconduct finding,” and explains that Continue reading Science Signaling corrects data fudged by former UCSF student

Animal welfare breach prompts Nature correction

cover_nature (1)A 2011 letter to Nature from Harvard researchers received its second correction today, this time after discovering the researchers conducted experiments in which mice may have “experienced more pain and suffering than originally allowed for.”

That quote comes from an accompanying editorial in the journal, a rare move for a correction to a 2011 letter. But it’s an unusual correction, for a letter that found that a component of a pepper plant appeared to selectively kill cancer cells, leaving healthy cells relatively unscathed.

Here’s the first paragraph from the detailed correction notice, published today: Continue reading Animal welfare breach prompts Nature correction

Fourth retraction for Einstein oncologist due to image manipulations

home_cover (1)Two papers on a potential cancer drug have been retracted following an investigation that found “inappropriate manipulation of bands in gels.”

This makes four retractions by our count for Roman Perez-Soler, an oncologist at the Einstein College of Medicine, and for co-author Yi-He Ling, whose current affiliation is unknown.

Their previous two retractions, which we reported on in 2013, were also for image manipulation. At the time, Perez-Soler told us that Ling “accepted full responsibility for the changes” and he had “returned to his home country.”

The fresh retraction notes, from Molecular Pharmacology, provide a few specifics about the figures that were manipulated this time around.

Continue reading Fourth retraction for Einstein oncologist due to image manipulations

Retraction no. 8 (and a 1/2) hits former Duke researcher Erin Potts-Kant

American Journal of Physiology - Lung Cellular and Molecular PhysiologyAnother retraction and a correction that retracts two figures — ie, a partial retraction — have been posted for Duke University lung researchers, Erin Potts-Kant and Michael Foster.

These latest notices move the count up to 8.5 retractions for Potts-Kant and 7.5 for Foster (counting the partial retraction as 1/2), along with the correction for both. In both cases and in a familiar note from previous retractions, authors found “potential discrepancies” between two sets of data (partial retraction) and study figures that weren’t “reliable” (retraction).

The retraction comes after the authors discovered problems with three of the study figures. In the corrected paper, the authors were able to validate some of their findings after repeating the experiments, but retracted two of the study figures that they were “unable to verify.”

Continue reading Retraction no. 8 (and a 1/2) hits former Duke researcher Erin Potts-Kant

“Obviously stolen” figure squashes mosquito paper in author’s second retraction

jmr-cover2015The Journal of Mosquito Research has retracted a paper because it contains a figure that “was obviously stolen” from another paper.

The retracted paper’s first author Emtithal M. Abd El-Samiee is now up to two retractions, by our count. Last month, we reported on her fruit fly paper, felled by a faulty gene sequence. On the paper, she is listed as an entomologist at Cairo University.

The note tells us where the figure was stolen from:

Continue reading “Obviously stolen” figure squashes mosquito paper in author’s second retraction

Plant paper pulled when authors can’t pay fees

KPSB_10_08_COVER.inddA paper on chicory plants — also known as “blue daisies” — won’t get its moment in the sun.

The “accepted author version” was published online in June, in Plant Signaling & Behavior. But before the so-called “version of record” could make it into an official issue of the journal — which is online-only — it was retracted.

Why? The authors apparently couldn’t pay the fees required to publish the paper. Here’s the short note, which is titled “Editorial Retraction:” Continue reading Plant paper pulled when authors can’t pay fees

5th retraction for Voinnet follows correction, EoC to PLOS Genetics paper

PLOS GeneticsAfter correcting a paper due to problematic figure panels, researchers led by high-profile biologist Olivier Voinnet have now retracted it, after “further analysis of the paper revealed flaws in the interpretation of” another figure.

PLOS Genetics published the retraction notice September 3 for the 2013 paper on the molecular details of embryonic stem cells in mice. First author Constance Ciaudo and Voinnet assume “full responsibility for the mistakes on this paper,” according to the note.

Continue reading 5th retraction for Voinnet follows correction, EoC to PLOS Genetics paper

Investigation leads to retraction of breast cancer paper, second for one author

Journal of Biological Chemistry.coverThe authors of a Journal of Biological Chemistry paper on a breast cancer gene are withdrawing it following an investigation at Roswell Park Cancer Institute that found a figure contained “manipulated” data.

Last author Toru Ouchi is based at Roswell in the department of cancer genetics.

Second to last author Sam W. Lee, at Massachusetts General Hospital, lost a Molecular Cell paper in 2013 after some figures were “inappropriately manipulated.”

Here’s the withdrawal note from JBC (which, unusually — but happily so — includes some explanation of what’s wrong with the paper): Continue reading Investigation leads to retraction of breast cancer paper, second for one author

Correction “does not change the scientific meaning” of leukemia letter

blood

The journal Blood has issued a correction in a 2009 letter about the molecular underpinnings of chronic lymphocytic leukemia.

Despite the extent of the changes to a figure, “the error does not change the scientific meaning,” according to the erratum.

The article “p73, miR106b, miR34a, and Itch in chronic lymphocytic leukemia” was written in response to a 2009 Blood paper about the role of a microRNA in CLL. But its western blots were “assembled incorrectly,” leading to duplicated panels. Another set of panels was “shifted.”

So the authors repeated the experiments, and presented them in a correction. Here’s the correction notice in full, published earlier this month, including the figures in question:

Continue reading Correction “does not change the scientific meaning” of leukemia letter

Stem cell researcher Jacob Hanna’s correction count updated to 10

Jacob Hanna
Jacob Hanna

Thanks to some eagle-eyed readers, we’ve been alerted to some corrections for high profile stem cell scientist Jacob Hanna that we had missed, bringing our count to one retraction and 13 errata on 10 papers.

The problems in the work range from duplications of images, to inadvertent deletions in figures, to failures by his co-authors to disclose funding sources or conflicts of interest. Hanna is the first or last author on 4 of the papers, and one of several on the rest.

First up, a correction to a Cell paper on which Hanna is the first author:

Continue reading Stem cell researcher Jacob Hanna’s correction count updated to 10