“The paper is extremely flawed:” Journal retracts article linked to vaccines

A journal has retracted a 2016 paper after receiving criticism from outside researchers who raised concerns about its methodology and data.

The paper shares multiple authors with another paper that linked the vaccine for human papillomavirus (HPV) to behavioral problems in mice. Last year, a journal removed the study; later that year, the authors published a revised version in another journal. The latest retracted paper focuses on the antibodies present in a form of lupus.

Yehuda Shoenfeld at Tel-Aviv University in Israel, the corresponding author on both this latest retraction and the HPV vaccine paper, recently edited a textbook that explored how vaccines can induce autoimmunity in some people.  He told us the 2016 lupus paper does have a link to vaccines [his emphasis]:

Continue reading “The paper is extremely flawed:” Journal retracts article linked to vaccines

Journal corrects paper by researcher sanctioned for misconduct

A biology journal has issued a correction to a 2014 paper by a researcher with 11 retractions, citing “inadvertent errors” that don’t affect the conclusions.

The researcher, Rony Seger, was recently sanctioned by his institution (The Weizmann Institute in Israel) following a finding of “serious misconduct” involving data manipulation. Specifically, the institute barred him from supervising graduate students, even future ones; his lab is now dedicated to replicating his previous work, with the help of a technician.

Last month, Michal Neeman, vice president of The Weizmann Institute of Science, told us she wasn’t sure how many additional papers by Seger would need to be retracted or corrected.

Recently, one more was revealed — in the August issue of Molecular and Cellular Biology, the following correction notice appears:

Continue reading Journal corrects paper by researcher sanctioned for misconduct

Scientist steps down from South Korea government position over criticism of her role in stem cell scandal

A professor at Sunchon National University has resigned from a prominent government position in South Korea after facing heavy criticism for being a co-author of a fraudulent stem cell paper.

Earlier this week, President Moon Jae-in appointed Park Ky-young to run a newly created Science, Technology and Innovation Office at the Ministry of Science and ICT. Critics quickly cried foul, noting that Park co-authored one of the stem cell papers by Woo-Suk Hwang, which made headlines 10 years ago after an investigation revealed the supposedly groundbreaking research had been fabricated.

According to the Korea Herald, Park’s position would have given her a say over the country’s R&D budget, worth 20 trillion won ($17 billion USD) in the science sector. The appointment does not require approval from parliament.

Today, Park agreed to step down. In a written statement, she said:

Continue reading Scientist steps down from South Korea government position over criticism of her role in stem cell scandal

Unearthed emails: Monsanto connected to campaign to retract GMO paper

A trove of internal documents from Monsanto, recently unsealed in a lawsuit against the agricultural biotech giant, has revealed the firm’s role in the knotty tale of a paper from the lab of a scientist known for his stance against genetically modified organisms (GMOs).

That paper is “Long term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize,” published in September 2012 in the journal Food and Chemical Toxicology (FCT) and retracted in January 2014. Gilles Seralini, a scientist known for an adversarial stance towards GMOs, was first author. The documents have also spurred the retraction of several pro-GMO articles on Forbes.com written by Henry Miller, a fellow at the Hoover Institution, a conservative think tank at Stanford University. Emails showed that one of the articles, which didn’t discuss Seralini’s paper, was ghostwritten by Monsanto.

The documents, posted last week by the law firm of Baum, Hedlund, Aristei and Goldman, show Monsanto engaged with a network of scientists and other commentators to spread the message that the Seralini paper was bad science and should be retracted. Seralini told Retraction Watch that this proves what he has been saying all along, that Monsanto led a concentrated effort to discredit his science and protect its bottom line. He said:

Continue reading Unearthed emails: Monsanto connected to campaign to retract GMO paper

Elsevier retracts entire issue after mistakenly publishing it online

Publishing giant Elsevier has retracted an entire issue of one of its journals because the contents — abstracts from a conference about child neurology — were never supposed to make it online.

We discovered the retraction after realizing that every aspect of the issue in Brain & Development had been retracted, including the cover, editorial board, and the contents.

We contacted Elsevier, and a spokesperson told us:

Continue reading Elsevier retracts entire issue after mistakenly publishing it online

Fearing “stigmatization,” patient’s father seeks retraction of paper on rare genetic mutation

The father of a boy with a rare genetic mutation has accused a scientist of exploiting his child by proclaiming the defect a “genetic syndrome” and naming it after herself.

At an impasse with scientists investigating, publicizing, and interpreting his son’s condition, the father seems willing to use any leverage he can muster to remove the “syndrome” entry in an online genetic disease database. Based solely on an email he obtained from the database director, the father became convinced that if the paper underpinning the entry were retracted, the syndrome would go down with it. So earlier this year, he withdrew his consent and asked the journal that published the paper for a retraction, based on improper patient consent. He has also threatened to lob accusations of research misconduct at the paper’s last author. Continue reading Fearing “stigmatization,” patient’s father seeks retraction of paper on rare genetic mutation

Third retraction for former rising star found guilty of misconduct

A once-prominent researcher in the field of infectious disease — who was found guilty of misconduct last year— has had a third paper retracted, a 2006 article in PNAS.

Last year, the University of Dundee in Scotland found that Robert Ryan had committed research misconduct, which included misrepresenting clinical data and duplicating images in a dozen different publications. After a failed attempt to appeal the decision, Ryan resigned.

In April, we covered Ryan’s first two retractions – a 2012 paper in Molecular Microbiology, which cited image errors, and a 2011 paper in Journal of Bacteriology, which cited image duplication.

Now, PNAS has retracted a 2006 paper, which cites potential image duplication as well as “irregularities” in the data.

Here’s the retraction notice for “Cell–cell signaling in Xanthomonas campestris involves an HD-GYP domain protein that functions in cyclic di-GMP turnover:”

Continue reading Third retraction for former rising star found guilty of misconduct

Researchers retract a paper when they realize they had sequenced the wrong snail’s genome

Researchers in China thought they had sequenced the genomes of two snails that help transmit diseases to other species — an important first step to stopping the spread. But their hopes were soon dashed after they realized they had misidentified one of the snails.

The researchers published their findings earlier this year in the journal Parasites & Vectors. In the paper, the authors stressed that understanding the genetic makeup of these molluscs is important because many “freshwater snails are intermediate hosts for flatworm parasites and transmit infectious diseases” to humans and other animals. They also acknowledged that identifying snail species from their appearance alone can be tricky. Continue reading Researchers retract a paper when they realize they had sequenced the wrong snail’s genome

“The article must be retracted:” Journal pulls prostate cancer study

A 2016 paper exploring the biology of prostate cancer has been retracted due to figure manipulation.

According to the retraction notice, a reader contacted the journal Clinical Cancer Research in late 2016 with concerns that similar bands appeared multiple times in two images. The editors asked the paper’s corresponding author, Shahriar Koochekpour, about the issue and requested the raw data for the figures. But Koochekpour, based in the Departments of Cancer Genetics and Urology at Roswell Park Cancer Institute in Buffalo, New York, at the time of the study, could not locate the raw data.

Since the lab did not have raw data from such a relatively recent paper, the editors reached out to the research integrity officer at Roswell Park Cancer Institute to investigate. Indeed,  the research integrity officer contacted confirmed that two figures were problematic, and requested the paper be retracted.

Here’s the rather detailed retraction notice, published in July 2017, for “GRM1 is An Androgen-Regulated Gene and its Expression Correlates with Prostate Cancer Progression in Pre-Clinical Models:” Continue reading “The article must be retracted:” Journal pulls prostate cancer study

“The data have spoken:” Controversial NgAgo gene editing study retracted

The author of a 2016 paper describing a potentially invaluable lab tool has retracted it, following heavy criticism from outside groups that could not reproduce the findings.

The paper had already been tagged with an Expression of Concern by the journal, Nature Biotechnology, which included data from multiple groups casting doubt on the original findings. Although the authors, led by Chunyu Han at Hebei University of Science and Technology in China, produced data to support their original findings, the journal has concluded — following “feedback from expert reviewers” — that the additional data “are insufficient to counter the substantial body of evidence that contradicts their initial findings,” according to an editorial released today:

Continue reading “The data have spoken:” Controversial NgAgo gene editing study retracted