Reverse tissue engineering: data reuse causes retractions of three papers from German organ researchers

The body count has reached three for a group of German tissue engineers who appear to have cloned their data in many of their publications.

Tissue Engineering Part A has retracted one of the papers from the investigators, titled “Clinically established hemostatic scaffold (tissue fleece) as biomatrix in tissue- and organ-engineering research,” which was published in 2003.

The notice states: Continue reading Reverse tissue engineering: data reuse causes retractions of three papers from German organ researchers

Controversial paper on life-extending buckyballs corrected after blog readers note problems

Back in April, a group of French and Tunisian researchers published a paper in Biomaterials which came to the astonishing conclusion that buckyballs (carbon tetrachloride) coated in olive oil could dramatically extend the lives of lab rodents. That news was picked up by Derek Lowe’s In the Pipeline blog, on which he expressed some bemusement about the work but ultimately praised it:

These are reasonable (but unproven) hypotheses, and I very much look forward to seeing this work followed up to see some more light shed on them. The whole life-extension result needs to be confirmed as well, and in other species. I congratulate the authors of this work, though, for giving me the most number of raised eyebrows I’ve had while reading a scientific paper in quite some time.

One of those eyebrows dropped a bit the following day, when Lowe reported that readers had pointed him to a clear case of image duplication in the article. At the time, Lowe concluded: Continue reading Controversial paper on life-extending buckyballs corrected after blog readers note problems

Wham, bam, no thank you, ram: Publisher error leads to retraction of already-withdrawn sheep sperm paper

Caution: Sexual innuendo ahead.

The withdrawal method is a notoriously unreliable form of birth control. It seems that what happens between the sheets applies to paper as well as cotton.

Here’s a retraction notice from BMC Research Notes that speaks — and nudges and winks — for itself. The 2011 article, “Effect of controlled and uncontrolled cooling rate on motility parameters of cryopreserved ram spermatozoa,” by a team of Irani veterinary scientists: Continue reading Wham, bam, no thank you, ram: Publisher error leads to retraction of already-withdrawn sheep sperm paper

Is post-hoc statistical analysis the new fraud detection tool? A new review looks at fraudster Reuben’s work

In the beginning, there was Scott Reuben.

Well, not quite. Reuben, a Massachusetts anesthesiologist who fabricated data and briefly topped our list of most-retracted authors, didn’t invent research fraud, although he did spend six months in federal prison for his crimes. But his case was in no small measure responsible for the birth of this blog, and, well, the rest of human history that followed.

Although Reuben’s retractions are behind him now — his count ends at 22 — and other scientists, including two anesthesiologists, Joachim Boldt and Yoshitaka Fujii, have or likely soon will dramatically eclipsed his mark, a new paper has revisited his publications with an eye toward seeing if they could identify statistical evidence of data manipulation. It’s the same  kind of effort that Ed Yong highlighted as noteworthy about the Dirk Smeesters case, which we covered yesterday and which involved an anonymous statistically inclined whistleblower.

Before we get to whether there was evidence of such manipulation Continue reading Is post-hoc statistical analysis the new fraud detection tool? A new review looks at fraudster Reuben’s work

Misconduct burns authors of wax paper, leads to sharply worded retraction notice

Philosophical Transactions of the Royal Society A is retracting a 2010 paper whose authors misappropriated data, forged an author name — and got a pretty strong backhand slap for the trouble.

The paper, “Green waxes, adhesives and lubricants,” which refers to eco-friendly materials, not Halloween-friendly slimes, was published by a group of researchers from China and Canada. Problem was, the one from Canada evidently didn’t know she was listed on the manuscript, and a big chunk of the work had been misappropriated from her university.

As the notice explains: Continue reading Misconduct burns authors of wax paper, leads to sharply worded retraction notice

JPET peeves: Paper withdrawn after drug company won’t disclose chemical structure

A group of researchers at the drug company ChemoCentryx is withdrawing a 2012 paper in the Journal of Pharmacology and Experimental Therapeutics over failure to appropriately identify the molecule they describe in the article.

The withdrawal notice tells the story: Continue reading JPET peeves: Paper withdrawn after drug company won’t disclose chemical structure

Three more Fujii papers fall for lack of IRB approval

Three journals under the JAMA umbrella are retracting papers by Yoshitaka Fujii, the Japanese anesthesiologist accused of research misconduct so sweeping that it might net him the record for most retractions by a single author.

The papers, in the Archives of Surgery, Archives of Ophthalmology and the Archives of Otolaryngology — Head & Neck Surgery, were published in 2001 and 2005.

Here are the notices, which are essentially identical but for the titles of the articles: Continue reading Three more Fujii papers fall for lack of IRB approval

Resveratrol researcher Das in video: Yes, I manipulated images, but only because the journals asked me to

Das, via UConn

Dipak Das, who until earlier this year ran a high-profile cardiovascular research center at the University of Connecticut, has recorded a slick looking video defense against allegations that he cooked data and manipulated images in scores of published studies, 12 of which have been retracted to date.

Das, who was hit with a 60,000 pages of allegations stemming from a three-year investigation by the university, spends the bulk of the documentary-style interview — which is available on YouTube — talking about the wonders of resveretrol. But he gets into the misconduct charges at about the 15-minute mark.

Continue reading Resveratrol researcher Das in video: Yes, I manipulated images, but only because the journals asked me to

PLoS ONE expresses concern over flu vaccine paper

via Wikimedia

PLoS ONE has issued an expression of concern over a  2010 paper by Chinese scientists about how the immune system responds to the vaccine against the swine flu.

The article, “Protection Induced on Day 10 Following Administration of the 2009 A/H1N1 Pandemic Influenza Vaccine,” claimed to study 58 subjects given the inoculation (more on that below) and that Continue reading PLoS ONE expresses concern over flu vaccine paper

Tell-tale hearts: Cardiology journals retract redundant articles

The European Journal of Cardiothoracic Surgery has retracted a 2007 article by Chinese researchers after the senior author decided he liked the data so nice he’d publish them twice. And he appears to have done so without the knowledge of the corresponding author.

Here’s the notice for the paper, titled “Open-heart surgery in patients with liver cirrhosis”: Continue reading Tell-tale hearts: Cardiology journals retract redundant articles