PNAS paper on potential breast cancer treatment retracted

The authors of a 2009 study in the Proceedings of the National Academy of Sciences (PNAS) have retracted the paper, which found a particular molecule could make breast tumors respond to a drug to which they’re not normally susceptible.

The paper — which has been cited five times, according to Thomson Scientific’s Web of Knowledge — was the subject of a fair amount of press coverage, although the molecule is not yet in clinical trials. In a Reuters story, lead author Caroline Ford said of the alleged tamoxifen-sensitizing compound, Foxy-5:

“It flips the switch basically,” Ford said in a telephone interview. “It makes breast cancer cells respond to tamoxifen in women who cannot be treated with the drug,” she added. “If you don’t have that molecule you can’t get tamoxifen because there is no target.”

According to the retraction notice, signed by all three of the study’s authors: Continue reading PNAS paper on potential breast cancer treatment retracted

Sultans of swap: List of plagiarized papers grows to include BMJ

Although some readers evidently have yawned at revelations that Vahdettin Bayazit, of Alparslan University in Turkey (and, we are tempted to assume, at least a few of his co-authors) appears to have plagiarized wantonly in numerous published articles, one follower of Retraction Watch was on to this case even before we were.

In an e-mail, the tipster laid out a picture of intellectual dishonesty audacious for both its scope and ham-handedness. The researcher, who wanted to remain anonymous, used Google to detect instances of plagiarism, just as we had, coming up with “more than 10” papers with passages stolen from the scientific literature and even Wikipedia, including not only lifted text but figures, too. And, just as in our case, the editors our source contacted about the misconduct have essentially ignored it.

We confess that we’re puzzled by the attitude that a little plagiarism is no big deal. As physician Andrew Burd writes in the BMJ today: Continue reading Sultans of swap: List of plagiarized papers grows to include BMJ

ORI comes down (hard) on Bengu Sezen, Columbia chemist accused of fraud

The Office of Research Integrity has thrown a heavy book at Bengu Sezen, a former chemist at Columbia University, alleging that school and agency investigators turned up 21 instances of research misconduct by the disgraced scientist.

According to the agency: Continue reading ORI comes down (hard) on Bengu Sezen, Columbia chemist accused of fraud

How much plagiarism should editors tolerate? A poll

Photo by captain.tucker via flickr http://www.flickr.com/photos/russell300d/

Over the past few weeks, you’d have been forgiven for wondering if the name of this blog should be “Plagiarism Watch” instead of Retraction Watch. Just take a look at all of the recent plagiarism cases:

That last example inspired this poll. When we brought an example of likely plagiarism by the same author to the attention of one journal editor, he was nonplussed. “[A]s all editors know there are rarely absolutely clear cut issues in which the line is unequivocally drawn in the sand,” said the editor-in-chief of Biomaterials, David Williams of Wake Forest. (Williams also suggested that the relative obscurity of the plagiarizers’ institution, and of the journal where they published, meant the case wasn’t worth investigating.)

So where is that line in the sand? Take our poll:

Sultans of swap: Turkish researchers plagiarized electromagnetic fields-cancer paper, apparently others

The Bosnian Journal of Basic Medical Sciences has retracted a paper it published in August by Turkish researchers on the potential cancer risks associated with exposure to electromagnetic fields, or EMFs.

The reason: Other people wrote nearly all of it.

According to an editor’s notice: Continue reading Sultans of swap: Turkish researchers plagiarized electromagnetic fields-cancer paper, apparently others

Update on a Best Of retraction: Elsevier edits notice suggesting renaming Israel “historical Palestine” was political

About two months ago, we posted an item on a curious retraction as the first installment in our Best of Retractions series. In the notice of the retraction in Agricultural Water Management, the editor wrote:

Reason: During the second revision of the manuscript, the authors modified Figure 1 (changing the label from “Israel” to  “Historical Palestine”), apparently with the goal of inserting a political statement into a scientific journal article. The authors did not inform the editors or the publisher of this change in their manuscript. As such, the authors have not lived up to the standards of trust and integrity that form the foundation of the peer-review process. The Editors-in-Chief take a very strong view on this matter and, hence, the retraction of the article from publication in Agricultural Water Management.

As Pieter van der Zaag, one of the paper’s authors informed us over the weekend in a comment on that post, however, the phrase “apparently with the goal of inserting a political statement into a scientific journal article” has now been removed from the notice. We asked van der Zaag, of the UNESCO-IHE Institute for Water Education, for some more information. Here are his comments: Continue reading Update on a Best Of retraction: Elsevier edits notice suggesting renaming Israel “historical Palestine” was political

After misrepresentation allegations, German anesthesiologist Joachim Boldt out as hospital’s chief physician

Ludwigshafen Hospital, via Wikimedia http://commons.wikimedia.org/wiki/File:Klinikum_Ludwigshafen_Nordseite.jpg

Joachim Boldt, a leading German anesthesiologist who had a 2009 paper in Anesthesia & Analgesia retracted last month* amid allegations  that he had misrepresented parts of the study, has been relieved of his duties as chief physician at Ludwigshafen Hospital.

A press release from the German Society for Anesthesiology and Intensive Care Medicine (DGAI) condemns Boldt’s actions. The press release goes on (translated from German): Continue reading After misrepresentation allegations, German anesthesiologist Joachim Boldt out as hospital’s chief physician

Update on Ahluwalia fraud case: Researcher faked results, probably committed sabotage, says UCL

Earlier this month, we posted an item about the retraction of a 2004 Nature paper, “The large-conductance Ca2+-activated K+ channel is essential for innate immunity.” (That post was followed up with provocative comments from a researcher not affiliated with the authors, about what should happen to papers whose results can’t be replicated.)

One of the paper’s authors, Jatinder Ahluwalia, hadn’t signed the retraction, and the notice referred to “Supplementary Information” that hadn’t yet been made available. Today, University College London (UCL) posted that supplementary information, which was the report of a panel that investigated charges of research misconduct against Ahluwalia. That report fills in a lot of details about what preceded the retraction.

Here’s the story: Continue reading Update on Ahluwalia fraud case: Researcher faked results, probably committed sabotage, says UCL

Plagiarists plagiarized: A daisy chain of retractions at Anesthesia & Analgesia

Self-plagiarism alert: A very similar version of this post is being published online in Anesthesiology News, where one of us (AM) is managing editor.

If a plagiarist plagiarizes from an author who herself has plagiarized, do we call it a wash and go for a beer?

That scenario is precisely what Steven L. Shafer found himself facing recently. Shafer, editor-in-chief of Anesthesia & Analgesia (A&A), learned that authors of a 2008 case report in his publication had lifted two-and-a-half paragraphs of text from a 2004 paper published in the Canadian Journal of Anesthesia.

A contrite retraction letter, which appears in the December issue of A&A, from the lead author, Sushma Bhatnagar, of New Delhi, India, called the plagiarism “unintended” and apologized for the incident. Straightforward enough.

But then things get sticky. Continue reading Plagiarists plagiarized: A daisy chain of retractions at Anesthesia & Analgesia

Do peer reviewers get worse with experience? Plus a poll

Peer review isn’t a core subject of this blog. We leave that to the likes of Nature’s Peer-to-Peer, or even the Dilbert Blog.  But it seems relevant to look at the peer review process for any clues about how retracted papers are making their way into press.

We’re not here to defend peer review against its many critics. We have the same feelings about it that Churchill did about democracy, aka the worst form of government except for all those others that have been tried. Of course, a good number of the retractions we write about are due to misconduct, and it’s not clear how peer review, no matter how good, would detect out-and-out fraud.

Still, peer review is meant as a barrier between low-quality papers and publication, and it often comes up when critics ask questions such as, “How did that paper ever get through peer review?”

With that in mind, a paper published last week in the Annals of Emergency Medicine caught our eye. Continue reading Do peer reviewers get worse with experience? Plus a poll