Rats! Neuroscientist notches third retraction, this one for using the wrong RNAs
Amine Bahi, a neuroscience researcher in the United Arab Emirates, has had a third paper retracted.
Here’s the notice for “Blockade of Protein Phosphatase 2B Activity in the Amygdala Increases Anxiety- and Depression-Like Behaviors in Mice,” which was posted on November 19:
This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy).
This article has been retracted at the request of Yale University and the second and third authors, in consultation with Biological Psychiatry Deputy Editor, Eric J. Nestler, MD, PhD.
Reason: The first author informed his co-authors and stated in the article that three short hairpin RNAs (shRNAs) (158–182 bp, 466–490 bp, 1452–1476 bp) had been designed to target the messenger RNA encoding CnA (NM_008915) and had been used in the experiments that formed the basis of the article. The first author has since acknowledged that he used shRNAs directed against rat calcineurin, not mouse calcineurin, in the experiments. Neither the second nor third author participated in or had knowledge of the first author’s actions.
The second an and third authors have re-conducted all experiments reported in the original paper in order to collect new data and republish the findings.
Bahi was the first author of the paper, which was written while he was a postdoc at Yale. The paper has been cited 18 times, according to Thomson Scientific’s Web of Knowledge.
The retraction is Bahi‘s third in three years. In 2011, one of his papers was retracted for “legal issues” that Bahi said were because Novartis didn’t want him to publish his findings. Last year, the cause was lack of animal research committee approval.