Category: image manipulation

Cancer journals retract 10 papers, flag 8 more, and apologize for the delay

Bharat Aggarwal

Five journals published by a prominent cancer research society have retracted a total of 10 papers — most of them by a former researcher at the MD Anderson Cancer Center in Houston.

Nine of the 10 retractions share that researcher, Bharat Aggarwal, as an author. Aggarwal — who more than five years ago threatened to sue us for reporting on an investigation into his work — is now up to 28 retractions, and has left his post at MD Anderson. The AACR is also appending an editor’s note to eight of his other papers — but it has not explained the reason for what it acknowledges is a lag in moving on these articles.

“Unfortunately, we have been delayed in correcting the published record, and for this we apologize,” writes the publisher of The American Association for Cancer Research (AACR), Christine Rullo, in a note in this month’s issue of Cancer Research. Rullo doesn’t say how long the journals took to handle the retractions. Continue reading Cancer journals retract 10 papers, flag 8 more, and apologize for the delay

After probe, journal removes flag from four papers, corrects manipulated images

Last year, Journal of Cell Science added notices to four papers after a reader contacted the editors with some concerns about issues with the figures. Now, it’s replacing the previous editorial notices with corrections, which address duplicated images and data.

When the journal issued expressions of concern for four papers co-authored by José Ignacio Rodriguez-Crespo about the allegations (which had also been raised on PubPeer), it notified his institution, the Universidad Complutense de Madrid (UCM). The newly issued correction notices explain that UCM investigated the four papers, and the data support the results and conclusions. In two cases, the authors supplied the original data, and in the others, they replicated the experiments.

Rodriguez-Crespo declined to comment, saying only that the journal

Continue reading After probe, journal removes flag from four papers, corrects manipulated images

35,000 papers may need to be retracted for image doctoring, says new paper

Elisabeth Bik

Yes, you read that headline right.

In a new preprint posted to bioRxiv, image sleuths scanned hundreds of papers published over a seven-year period in Molecular and Cellular Biology (MCB), published by the American Society for Microbiology (ASM). The researchers — Arturo Casadevall of Johns Hopkins University, Elisabeth Bik of uBiome, Ferric Fang of the University of Washington (also on the board of directors of our parent non-profit organization), Roger Davis of the University of Massachusetts (and former MCB editor), and Amy Kullas, ASM’s publication ethics manager — found 59 potentially problematic papers, of which five were retracted. Extrapolating from these findings and those of another paper that scanned duplication rates, the researchers propose that tens of thousands of papers might need to be purged from the literature. That 35,000 figure is double the amount of retractions we’ve tallied so far in our database, which goes back to the 1970s. We spoke with the authors about their findings — and how to prevent bad images from getting published in the first place.

Retraction Watch: You found 59 potential instances of inappropriate duplication — how did you define this, and validate that the images were problematic?

Continue reading 35,000 papers may need to be retracted for image doctoring, says new paper

Dental journal pulls a dozen papers for recycled images and “unreliable data”

A leading orthodontics journal has retracted 12 papers after determining that they contained either reused images, questionable data or both. Several of the articles involved experiments conducted in dogs — and one person familiar with the case told us that the duplication was an attempt to avoid sacrificing more animals than necessary for the research.  

Although the list of authors on the articles varies, the common denominator is Jose Luis Calvo-Guirado, of the UCAM Universidad Católica San Antonio de Murcia, in Spain. Calvo-Guirado’s title at the institution is director de la Cátedra Internacional de Investigación en Odontología, which Google translates as director of the International Research Chair in Dentistry.  Calvo-Guirado also holds (or has held) a research professorship at SUNY Stony Brook in the Department of Prosthodontics and Digital Medicine, according to his CV.

Calvo-Guirado’s name is on at least 187 entries in PubMed. Of those, 40 appeared in Clinical Oral Implants Research, a Wiley title on whose editorial board the researcher served, according to his CV.  

Continue reading Dental journal pulls a dozen papers for recycled images and “unreliable data”

University requests 20 retractions of cancer papers following probe

Santosh Katiyar

A university and medical center have requested a batch of retractions following an investigation that found 20 papers by a cancer researcher contained manipulated images.

The request, from University of Alabama, Birmingham (UAB) and Birmingham VA Medical Center, focuses on papers by Santosh Katiyar, who explored alternative approaches to treating skin cancer in animal models.

For more, see our story out today in The Scientist.

Continue reading University requests 20 retractions of cancer papers following probe

Mount Sinai multiple sclerosis researcher admits to misconduct

Gareth John

A researcher who has received millions in funding from the U.S. National Institutes of Health and who runs a lab at the Icahn School of Medicine at Mount Sinai in New York has confessed to falsifying data in a 2014 paper.

Gareth John, who studies multiple sclerosis and other neurological diseases, “has expressed remorse for his actions,” according to a report released last week from the U.S. Department of Health and Human Services’ Office of Research Integrity. Continue reading Mount Sinai multiple sclerosis researcher admits to misconduct

Controversial Australian science journalist admits to duplication in her PhD thesis

Maryanne Demasi

A prominent (yet controversial) journalist in Australia has admitted to duplicating three images that were part of her PhD thesis — a practice outside experts agreed was acceptable, if not ideal, at the time, according to a report released today.

As part of an inquiry, the University of Adelaide convened an expert panel to investigate 17 allegations of duplication and/or manipulation in Maryanne Demasi’s 2004 thesis. Duplication is a common reason for retractions, such as when researchers use the same image to depict the results of different experiments.

After earning her PhD in rheumatology, Demasi became a journalist who got headlines for more than just her reporting. In 2013, she produced a controversial series about cholesterol and fat (which suggested they have been unfairly villainized, and which cast doubt on cholesterol-lowering drugs known as statins). A few years later, Demasi was fired from the science program Catalyst, after it aired an episode alleging wi-fi could cause brain tumors.

Regarding the allegations of misconduct in Demasi’s thesis, the originals of the images in question were long gone, so in 14 instances, an expert concluded it was not possible to conclude whether or not duplication had occurred. But in the remaining three instances, Demasi admitted she had “duplicated or probably duplicated” the images:

Continue reading Controversial Australian science journalist admits to duplication in her PhD thesis

Researcher loses battle with Cell over wording of retraction notice

For months, a researcher has wrestled with a journal over the wording of an upcoming retraction notice. It appears that she has lost.

Earlier this week, Cell retracted the paper, despite the protests of first author Shalon Babbitt Ledbetter. When Ledbetter learned the journal was planning to retract the biochemistry paper over image manipulations, but wouldn’t name the culprit in the notice, she shared her concerns on PubPeer. Although a 2015 letter sent to Cell from Saint Louis University identified last author Dorota Skowyra as responsible for multiple manipulations, the journal wasn’t planning to say Skowyra was responsible in the retraction notice. Which would leave all other authors — particularly Ledbetter — under a cloud of suspicion.

Now, Cell Press has finally retracted the paper, along with another paper in Molecular Cell that lists Skowyra as corresponding author. Both notices describe image manipulations that were investigated by Saint Louis University (SLU). Neither identifies who is responsible.

Continue reading Researcher loses battle with Cell over wording of retraction notice

Caught Our Notice: 54 problems in three scientific images equals one expression of concern

Title: Effects of microRNA-223 on morphine analgesic tolerance by targeting NLRP3 in a rat model of neuropathic pain

What Caught Our Attention: Usually, an Expression of Concern (EOC) offers general language about “concerns regarding the validity of the data” or “concerns regarding the integrity of the study.” Here the language is anything but, saying that 54 Western blot bands within three figures have problems such as “visible pasted joints,” “square border,” and numerous “appear to be the same band.”  According to the notice, the authors have not responded to requests for the original blots, so the editors are allowing the article to remain intact, choosing instead “to alert readers to these issues and allow them to arrive at their own conclusions regarding the figures.” Continue reading Caught Our Notice: 54 problems in three scientific images equals one expression of concern

In what appears to be a first, researcher sanctioned twice by ORI

Here’s something we haven’t seen before: The U.S. Office of Research Integrity has issued a second notice for a former researcher at the National Institutes of Health, after determining she withheld information during the first investigation.

Last year, the ORI sanctioned Brandi M. Baughman — formerly at the National Institute of Environmental and Health Sciences — after she “falsified and/or fabricated data” in 11 figures in a 2016 paper. Sanctions included agreeing to have her research supervised for three years. Now, the agency has barred her from receiving federal grants for two years. The reason:

Continue reading In what appears to be a first, researcher sanctioned twice by ORI