Category: ori investigations

ORI findings lead to two retractions — nearly 17 years later

Well, it only took 17 years.

As two retraction notices in the September 15 issue of the Journal of Immunology note:

On October 19, 1995, the Office of Research Integrity at the National Institutes of Health found that Weishu Y. Weiser, Ph.D., formerly of the Harvard Medical School at Brigham and Women’s Hospital, committed scientific misconduct by falsifying data in biomedical research supported by two Public Health Service grants. As a result, she agreed to submit a letter to The Journal of Immunology to retract this article. The offices of The Journal of Immunology have no record of receiving such a letter and hence the article is now being retracted.

The retractions, for “Recombinant Migration Inhibitory Factor Induces Nitric Oxide Synthase in Murine Macrophages” and “Human Recombinant Migration Inhibitory Factor Activates Human Macrophages to Kill Leishmania donovani,” both say the same thing.

“Recombinant Migration Inhibitory Factor Induces Nitric Oxide Synthase in Murine Macrophages” has been  cited 66 times, according to Thomson Scientific’s Web of Knowledge — 40 of those times since the ORI’s report was released. The numbers for the Leishmania paper are almost identical: Continue reading ORI findings lead to two retractions — nearly 17 years later

Former Harvard psychology prof Marc Hauser committed misconduct in four NIH grants: ORI

Two years after questions surfaced about work by former Harvard psychology professor Marc Hauser, an official government report is finally out.

It’s not pretty.

The findings by the Office of Research Integrity were first reported by the Boston Globe, which was also first to report the issues in Hauser’s work. They’re extensive, covering misconduct in four different NIH grants (we’ve added some links for context): Continue reading Former Harvard psychology prof Marc Hauser committed misconduct in four NIH grants: ORI

ORI finds Harvard stem cell lab post-doc Mayack manipulated images

courtesy Nature

Shane Mayack, a former post-doc in Harvard lab of Amy Wagers, a rising star in the stem cell field, has been sanctioned by the Office of Research Integrity for misconduct.

Mayack, who has defended her actions on this blog as honest error — albeit sloppiness — and has not admitted to wrongdoing, must undergo supervision if she receives any federal grant funding over the next three years, under the voluntary agreement.

Here’s the notice, which appeared in the Federal Register this week (and which the Boston Globe was first to report): Continue reading ORI finds Harvard stem cell lab post-doc Mayack manipulated images

How can institutions prevent scientific misconduct?

There has been plenty of interest in scientific fraud and misconduct lately — and not just on Retraction Watch — from major news outlets and government agencies, among other parties. The rate of retractions is increasing, and some fraudsters are even setting new records. That has focused attention on how institutions can prevent misconduct — not something anyone thinks is easy to do.

To try to figure it out, Columbia University’s Donald Kornfeld decided to review 146 U.S. Office of Research Integrity (ORI) cases from 1992 to 2003, “based on 50 years of clinical experience in psychiatry and 19 years as the chairman of two institutional review boards.” (Of note, these only represent cases in which ORI concluded there was misconduct, as the agency doesn’t report on negative cases.) Here’s what he found, reported last month in Academic Medicine: Continue reading How can institutions prevent scientific misconduct?

ORI finds Parkinson’s-pesticides researcher guilty of faking data; two papers to be retracted

The U.S. Office of Research Integrity (ORI) has found that a neuroscientist who studied the effects of pesticides on a mouse model of Parkinson’s disease made up data.

As The Scientist reported on Friday, the ORI found that Mona Thiruchelvam faked cell counts in two grant applications and a number of papers that claimed to show how the pesticides paraquat, maneb, and atrazine might affect parts of the brain involved in Parkinson’s. The Scientist notes: Continue reading ORI finds Parkinson’s-pesticides researcher guilty of faking data; two papers to be retracted

ORI sanctions Oregon eye stem cell researcher for faking data in grant applications

Peter Francis

Peter Francis, a former Oregon Health Sciences University (OHSU) eye researcher, has been sanctioned by the U.S. Office of Research Integrity (ORI) for claiming, in grant applications, to have performed experiments that he hadn’t actually done.

According to ORI’s case summary, Francis Continue reading ORI sanctions Oregon eye stem cell researcher for faking data in grant applications

ORI roundup: Former SUNY grad student, two Kansas U researchers hit with sanctions

In two unrelated cases, the Office of Research Integrity (ORI) has sanctioned a grad student and a pair of colleagues, one of whom plagiarized and the other allowed the intellectual theft to go unchecked.

We think the handling of these cases — both first noted briefly by The Chronicle of Higher Education — is worth noting.

Continue reading ORI roundup: Former SUNY grad student, two Kansas U researchers hit with sanctions

So how peripheral was Dipak Das’ resveratrol work, really?

In the wake of the massive allegations of fraud by resveratrol researcher Dipak Das, other researchers in the field are clearly trying to distance themselves from the University of Connecticut scientist. Nir Barzilai told us yesterday, for example, that despite Das seemingly’ impressive publication record, “Rome was not built on Dr. Das.”

Harvard’s David Sinclair went further, telling The New York Times that he didn’t know who Das was: Continue reading So how peripheral was Dipak Das’ resveratrol work, really?

Resveratrol fraud case update: Dipak Das loses editor’s chair, lawyer issues statement refuting all charges

Das, via UConn

Many Retraction Watch readers will now be familiar with the case of Dipak Das, the resveratrol researcher about whom the University of Connecticut issued a voluminous report yesterday — summary here — detailing 145 counts of data fabrication and falsification. This has been a fast-moving story, so we wanted to highlight a number of updates to our original post, and offer a few more.

First, we have confirmed with publisher Mary Ann Liebert this morning that Das has been relieved of his duties as co-editor in chief of Antioxidants & Redox Signaling. He had shared that post with Chandan Sen, and his name as been removed from the masthead of that journal. Here’s a statement from the publisher: Continue reading Resveratrol fraud case update: Dipak Das loses editor’s chair, lawyer issues statement refuting all charges

ORI comes down (hard) on Bengu Sezen, Columbia chemist accused of fraud

The Office of Research Integrity has thrown a heavy book at Bengu Sezen, a former chemist at Columbia University, alleging that school and agency investigators turned up 21 instances of research misconduct by the disgraced scientist.

According to the agency: Continue reading ORI comes down (hard) on Bengu Sezen, Columbia chemist accused of fraud