UCSF-VA investigation finds misconduct in highly cited PNAS paper

PNAS has corrected a highly cited paper after an investigation found evidence of misconduct.

The investigationconducted jointly by the University of California, San Francisco, and the San Francisco Veterans Administration Medical Centeruncovered image manipulation in Figure 2D, which “could only have occurred intentionally.” The institutions, however, could not definitively attribute the research misconduct to any individual.

According to the notice, the UCSF-VA committee determined that a correction to the 2008 PNAS paperwhich explores the genetic underpinnings of prostate cancerwas “appropriate,” and the authors have now replaced the problematic figure with a corrected version. The 2008 paper has been cited 630 times, according to Clarivate Analytics’ Web of Science.

A spokesperson for PNAS told Retraction Watch: Continue reading UCSF-VA investigation finds misconduct in highly cited PNAS paper

Probe finds misconduct in eight papers by researcher in Sweden

Suchitra Sumitran-Holgersson, via the University of Gothenburg

An external probe has concluded that a researcher based at the University of Gothenburg committed misconduct in multiple papers, all of which should be withdrawn.

Among 10 papers by Suchitra Sumitran-Holgersson at the University of Gothenburg, an Expert Group concluded that eight contained signs of scientific misconduct. The Expert Group, part of Sweden’s Central Ethical Review Board, also found evidence of problems within her laboratory environment.

In an email to Retraction Watch, Sumitran-Holgersson denied any “willful manipulation of data.”

According to the report (in Swedish, which we translated using Google):

Continue reading Probe finds misconduct in eight papers by researcher in Sweden

“Clear signs of manipulation” in paper co-authored by prominent geneticist

David Latchman

A third paper co-authored by researchers based at a prominent lab whose work has been under investigation on and off for almost three years has been retracted.

According to the notice, the university’s investigation found that a 2008 paper in FEBS Letters contained “clear signs of manipulation” in three figures.

Research from geneticist David Latchman’s group has been dogged by misconduct allegations since late 2013 and subject to two investigations by the University College London (UCL). Continue reading “Clear signs of manipulation” in paper co-authored by prominent geneticist

Former NYU researcher falsified data in 3 papers, 7 grants: ORI

A former researcher at New York University falsified and/or fabricated data in multiple papers and grant applications, according to the U.S. Office of Research Integrity.

Bhagavathi Narayanan has already retracted three papers, the result of missing original data. Among the three papers flagged by the ORI, only one remains intact: A 2011 paper in Anticancer Research.

According to the ORI:

Continue reading Former NYU researcher falsified data in 3 papers, 7 grants: ORI

Delays, arguing over upcoming Cell retraction leave first author “devastated”

After being “blindsided” a few months ago when she was told one of her 2005 papers was going to be retracted, a researcher scrambled to get information about why. And when she didn’t like the answers, she took to PubPeer.

Eight days ago, Shalon (Babbitt) Ledbetter, the first author of the 2005 paper published in Cell, posted a comment on the site announcing the paper was going to be retracted after the last author’s institution, Saint Louis University (SLU), determined that some figures had been manipulated by the last author, Dorota Skowrya. A letter dated September 2, 2015 sent by SLU to Cell describes the results of the investigation — namely, that the manipulations were “cosmetic,” and had no effect on the data or the conclusions. More than two years later, Ledbetter learned the journal was planning to retract the paper, and an initial draft of the notice wouldn’t identify who was responsible; she has since been pulled into a confusing web of blame-shifting and conflicting information that has been, in her words, “heartbreaking.”

Ledbetter wrote on PubPeer:

Continue reading Delays, arguing over upcoming Cell retraction leave first author “devastated”

Probe into Carlo Croce reached “defensible and reasonable” decisions, says external review

An independent analysis of how The Ohio State University reviewed allegations of misconduct against a high-profile cancer researcher has found that the institution “complied with applicable law and with relevant institutional policies and reached reasoned and supportable conclusions.”

The review follows numerous allegations of research misconduct against Carlo Croce, described in a March 8 story in the New York Times. According to the Times article, Croce has been the subject of multiple investigations; at least five of those inquiries from OSU cleared him of wrongdoing. 

Croce has denied the allegations, and is now suing the New York Times and an outside researcher who served as a key source in the story. As a result of the story, however, OSU — where Croce is basedtold us last year it had “launched an independent review of our systems for ensuring research integrity.”

Continue reading Probe into Carlo Croce reached “defensible and reasonable” decisions, says external review

Journal investigating earlier work by author of discredited fish-microplastics paper 

A biology journal is investigating concerns about a 2014 paper by a marine biologist who was found guilty of misconduct last year.

In December, Uppsala University concluded that Oona Lönnstedt had fabricated the results” of a controversial 2016 Science paper (now retracted), which examined the harms of human pollution on fish. (Lönnstedt’s supervisor Peter Eklöv was also found guilty of misconduct and had a four-year government grant terminated.) Continue reading Journal investigating earlier work by author of discredited fish-microplastics paper 

Florida investigation can’t ID culprit who falsified data in retracted PNAS paper

When the Proceedings of the National Academy of Sciences retracted a gene therapy paper in December, it declared that some of the data had been falsified and mentioned a research misconduct investigation. But the notice said nothing about who was responsible.

Via a public records request, Retraction Watch has obtained investigation documents from the University of Florida, which show the focus had been narrowed down to two of the paper’s three co-first authors. But the investigation committee didn’t assign blame to either one. According to their final report, dated Oct. 24, 2016:

there was not enough direct evidence to either implicate or exonerate either of these individuals.

Over the course of the formal investigation, which lasted from early August to late October 2016,  the committee was able to determine that data in the PNAS paper had been falsified. However, it said: Continue reading Florida investigation can’t ID culprit who falsified data in retracted PNAS paper

Macchiarini, 3 co-authors found guilty of misconduct in 2015 paper

The Karolinska Institutet in Sweden has declared that once-lauded surgeon Paolo Macchiarini and three co-authors committed misconduct in a 2015 paper.

The decision by KI’s vice chancellor will be followed by a request to retract the paper, published by the journal Respiration.

In the paper, the researchers described the case of a man with an acute lung disorder, in which he received an experimental treatment involving the use of his own blood-derived cells and the drug erythropoietin, which stimulates the production of red blood cells. The patient “demonstrated an immediate, albeit temporary, clinical improvement,” according to the authors. However, he ultimately died of multisystem organ failure.

Continue reading Macchiarini, 3 co-authors found guilty of misconduct in 2015 paper

Who reports more misconduct: Scientists in industry or academia?

Simon Godecharle

Who will admit to keeping poor records, gifting authorship, or even more obvious forms of misconduct such as plagiarism? Simon Godecharle at University of Leuven and his colleagues asked 2000 scientists from academia and industry in Belgium, and reported their findings in a recent paper for Science and Engineering Ethics. We spoke to Godecharle about the fact that most respondents admitted to engaging in at least one of the 22 items designated as misconduct — and why he thinks people in academia were more likely to ‘fess up than industry scientists.

Retraction Watch: You didn’t limit misconduct to fraud and plagiarism, and instead included problematic behaviors such as cutting corners to save time, gift authorship, and poor record-keeping. Still, you showed that 71% of respondents from academia and 61% of respondents from industry admitted to engaging in at least one of the 22 forms of misconduct. Did those numbers surprise you?

Continue reading Who reports more misconduct: Scientists in industry or academia?