Resveratrol fraud case update: Dipak Das loses editor’s chair, lawyer issues statement refuting all charges

Das, via UConn

Many Retraction Watch readers will now be familiar with the case of Dipak Das, the resveratrol researcher about whom the University of Connecticut issued a voluminous report yesterday — summary here — detailing 145 counts of data fabrication and falsification. This has been a fast-moving story, so we wanted to highlight a number of updates to our original post, and offer a few more.

First, we have confirmed with publisher Mary Ann Liebert this morning that Das has been relieved of his duties as co-editor in chief of Antioxidants & Redox Signaling. He had shared that post with Chandan Sen, and his name as been removed from the masthead of that journal. Here’s a statement from the publisher: Continue reading Resveratrol fraud case update: Dipak Das loses editor’s chair, lawyer issues statement refuting all charges

Journal retracts heart stem cell paper (and pulls no punches) over image fraud

Some retractions beg for a kick of sand in the face, and others do the kicking. Here’s an example of what Charles Atlas might have written had he been a journal editor concerned with research integrity.

Experimental Biology and Medicine, the official journal of the Society for Experimental Biology and Medicine, has retracted a 2010 article by a group of stem cell scientists in China with an unfortunate affinity for a particular figure—one they’d used in a previous publication, only with a different description.

Here’s the notice for the paper, “Isolation and characterization of multipotent progenitor cells from the human fetal aorta wall,” which was cited five times before it was retracted, according to Thomson Scientific’s Web of Knowledge: Continue reading Journal retracts heart stem cell paper (and pulls no punches) over image fraud

Chronic fatigue syndrome-XMRV paper retracted by Science, completely this time

The editors of Science have fully retracted a study they published in 2009 alleging a link between chronic fatigue syndrome (CFS) and the virus XMRV.

The notice begins with a nod to the reasons that the paper has already been partially retracted:

Science is fully retracting the Report “Detection of an infectious retrovirus, XMRV, in blood cells of patients with chronic fatigue syndrome” (1). Multiple laboratories, including those of the original authors (2), have failed to reliably detect xenotropic murine leukemia virus–related virus (XMRV) or other murine leukemia virus (MLV)–related viruses in chronic fatigue syndrome (CFS) patients. In addition, there is evidence of poor quality control in a number of specific experiments in the Report. Fig. 1, table S1, and fig. S2 have been retracted by the authors (3).

It also refers to evidence of image manipulation that was described by blogger Abbie Smith and then reported in the Chicago Tribune:

Continue reading Chronic fatigue syndrome-XMRV paper retracted by Science, completely this time

Another Hattori retraction over reused figure from cardiology pub

Another paper in Diabetologia by Yoshiyuki Hattori has been retracted for image duplication, marking the second of his articles in the journal to be pulled for that reason.

The notice for the article, “A glucagon-like peptide-1 (GLP-1) analogue, liraglutide, upregulates nitric oxide production and exerts anti-inflammatory action in endothelial cells,” states: Continue reading Another Hattori retraction over reused figure from cardiology pub

Cardiff University misconduct investigation leads to Journal of Immunology retraction

The senior author of a Journal of Immunology paper has retracted it after a university investigation found that he had inappropriately manipulated images, Retraction Watch has learned.

Here’s the notice: Continue reading Cardiff University misconduct investigation leads to Journal of Immunology retraction

Bulfone-Paus retraction count grows to 13 with one in Transplantation

Silvia Bulfone-Paus, the Borstel Institute researcher who was forced to step down as institute director and has already retracted 12 papers, has retracted another, this one in Transplantation. Here’s the text of the notice: Continue reading Bulfone-Paus retraction count grows to 13 with one in Transplantation

Corrections in PLoS One, Nature Medicine for Zhiguo Wang, and details about Montreal Heart Institute investigation

via Wikimedia

PLoS One and Nature Medicine have issued corrections for papers by Zhiguo Wang, the former Montreal Heart Institute researcher who resigned in September following an investigation into image manipulation in his lab. 

In September, PLoS One told us that they were investigating the paper. Here’s the text of the correction for “Transcriptional and Post-Transcriptional Mechanisms for Oncogenic Overexpression of Ether À Go-Go K+ Channel:” Continue reading Corrections in PLoS One, Nature Medicine for Zhiguo Wang, and details about Montreal Heart Institute investigation

New retraction sheds light on Medical College of Georgia vascular biology case

In late January, we wrote a post about a retraction in the journal Molecular Endocrinology involving work from the lab of Stephen M. Black, of the Vascular Biology Center at at the Medical College of Georgia.

At the time, we didn’t know much. The notice was pretty thin sauce, although it hinted at “significant concerns with the data,” and we were led to believe that the first author of the article, Neetu Sud, a post-doc in Black’s lab, might have been implicated in those concerns. Because Black’s lab was working with substantial amounts of NIH funding, the prospect of an investigation by the Office of Research Integrity seemed likely.

Now we have a little more to go on. The American Journal of Physiology: Lung Cellular and Molecular Physiology has retracted another article by Sud and Black. The paper, titled “Protein kinase Cδ regulates endothelial nitric oxide synthase expression via Akt activation and nitric oxide generation,” appeared in 2008 and included a third author, Stephen Wedgwood, of Northwestern University. It has been cited 10 times, according to Thomson Scientific’s Web of Knowledge.

Here’s the notice: Continue reading New retraction sheds light on Medical College of Georgia vascular biology case

Second retraction arrives in Alirio Melendez case

Alirio Melendez, whose former employer, the National University of Singapore, is investigating about 70 of his papers, has retracted a second study. Here’s the notice for the 2010 Journal of Molecular Cell Biology paper, “Sphingosine-1-phosphate mediates proliferation maintaining the multipotency of human Adult Bone Marrow and Adipose Tissue-derived Stem Cells:” Continue reading Second retraction arrives in Alirio Melendez case

Following investigation, U Ottawa lab retracting four papers in the Journal of Biological Chemistry

A University of Ottawa lab has been forced to retract four papers from the Journal of Biological Chemistry (JBC) after an investigation of image manipulation.

According to an email from a university official obtained by Retraction Watch, a university investigative committee had “found substance to the allegations,” although it claimed it could not disclose details “due to their confidentiality.” The university requested that the JBC withdraw a November 2005 paper, and left it to the journal to “determine whether the other articles should also be withdrawn or if they can be corrected. ” And they took the issue to the agency that funded the work: Continue reading Following investigation, U Ottawa lab retracting four papers in the Journal of Biological Chemistry