Dispute over author order torpedoes paper on syndrome linked to autism

At least one disgruntled co-author has triggered the retraction of a paper presenting a novel approach to treating a rare, genetically inherited condition.

The paper concerned research on Fragile X syndrome (FXS), characterized by both intellectual and physical abnormalities, which is linked autism. A compound that passed through phase 2 clinical trials in October 2015 appeared to partially treat FXS in mice in the study, published earlier this year.

The journal’s notice says the paper was retracted over a dispute among authors about the order in which they are listed on the paper: Continue reading Dispute over author order torpedoes paper on syndrome linked to autism

Miffed at exclusion from a meta-analysis, researcher writes own “expression of concern”

On June 10, Psycho-Oncology, a journal that publishes research on the “psychological, social, behavioral, and ethical” side of cancer, received a complaint.

In a letter, Ad Kaptein, a researcher at the Leiden University Medical Centre, in the Netherlands, wrote to say that a review and meta-analysis published by the journal that month hadn’t adequately cited the relevant literature in the field, including seven studies co-authored by Kaptein himself. The authors of the original paper say they had considered citing Kaptein’s work but decided against it, for various reasons.

The journal considered Kaptein’s complaint valid enough to publish his letter. But the letter carries the title “Expression of concern” — a term usually reserved for editorial notices issued by the journal to warn readers about some aspects of an article. But in this case, the author supplied the term, not the journal — yet the letter is tagged as an Expression of Concern on PubMed, giving the impression the paper has received a formal editorial notice.

Journal Co-Editor Maggie Watson told Retraction Watch:

Continue reading Miffed at exclusion from a meta-analysis, researcher writes own “expression of concern”

Chemistry journal issues correction longer than original paper

A 2011 chemistry paper required corrections so extensive that the author published the changes as a second, longer paper.

Both papers, published in the Chinese Journal of Chemistry, described the synthesis of a protein molecule with potential therapeutic applications in cancer. But when the paper’s corresponding author Yikang Wu tried to continue the work, he discovered that a substantial part of the 2011 study was incorrect.

The original paper is not marked with any editor’s note, even though the new paper — which is three pages longer than the 2011 version — acknowledges it is a “partial retraction/correction of previous results.” The new paper does appear in the list of “related content” for the 2011 article.

Given the errors, in the 2017 paper, Wu and his co-authors write: Continue reading Chemistry journal issues correction longer than original paper

Two more retractions for former US prof who altered dozens of images

Two journals have retracted papers by a biologist who was recently found guilty of misconduct by his former employer, the University of Colorado Denver, bringing the total to five.

The investigation report by UC Denver, which we obtained earlier this year via a public records request, had recommended one of the two newest retractions, which appears in the journal Hepatology. The other retraction, in the Journal of Immunology, was not flagged by the report — which found, among other conclusions, that Almut Grenz had altered multiple values in research that had already been submitted for peer review.

Here’s the notice for the Journal of Immunology paper:

Continue reading Two more retractions for former US prof who altered dozens of images

Former MD Anderson researcher objects to retraction of his paper

A cell biology journal has retracted a 2016 paper after an investigation revealed that the corresponding author failed to include two co-authors and acknowledge the funding source.

According to the retraction notice, the Journal of Cellular Physiology retracted the paper after the University of Texas, MD Anderson Cancer Center found that last author Jin Wang had omitted two researchers from the list of authors, and had also failed to acknowledge funding from the U.S. National Institutes of Health (NIH).

But Wang tells a different story. Continue reading Former MD Anderson researcher objects to retraction of his paper

Released FDA docs reveal details of agency’s (failed) attempt to retract paper

Earlier this year, a raging controversy regarding a new drug spilled into the pages of a leading medical journal: the head of the U.S. Food and Drug Administration and another official publicly called for the retraction or correction of a peer-reviewed article about the drug. They didn’t get their wish. Now, documents released by the FDA via a lawsuit shed light on the attempt — and show how tricky it can be to correct the official record.

The controversy surrounds the approval of eteplirsen, a drug approved last September to treat Duchenne Muscular Dystrophy, a rare but invariably fatal disease that strikes (mostly) young boys. Eteplirsen was approved over the objections of the FDA team that reviewed the drug, which determined that there was insufficient evidence to approve the drug.

But the controversy didn’t end within the walls of the FDA complex. Ellis Unger, who led the review team, believed that one of the principal studies of the drug, published in the Annals of Neurology, was “misleading” because it was based on “unreliable data.” So in early November, Unger, joined by the then-head of the FDA, Robert Califf, took the extremely rare move of writing to the editor of the journal to “urge that the paper be corrected or retracted….”

According to the documents, the authors of the Annals article did, in fact, agree to correct the article.

On November 9, 2016, Clifford Saper, Annals‘ editor in chief, wrote to Califf and Unger:

Continue reading Released FDA docs reveal details of agency’s (failed) attempt to retract paper

Uni dings schizophrenia studies for problems with informed consent, other flaws

Psychiatry journals have retracted two papers evaluating a schizophrenia drug after a university in Japan flagged issues, such as a lack of written informed consent.

The papers—published in Human Psychopharmacology: Clinical & Experimental in 2012 and Psychiatry and Clinical Neurosciences in 2014—examined the safety and effectiveness of an antipsychotic drug in patients with schizophrenia.

According to the retraction notice in Psychiatry and Clinical Neurosciences, the ethics committee at St. Marianna University School of Medicine in Kawasaki found that “the trial included subjects who did not satisfy inclusion criteria.” For instance, not all patients provided written informed consent. But the university found no evidence for data falsification or fabrication.

A spokesperson for Human Psychopharmacology told us: Continue reading Uni dings schizophrenia studies for problems with informed consent, other flaws

Want to appeal a journal’s rejection? Sure — that’ll be $700

Different journals follow different editorial policies — but we’ve never seen any charge money to authors who want to appeal an editorial decision. Until now.

Recently, a criminal justice researcher sent us links to multiple journals that charge appeal fees. For instance, the Journal of Accounting Research says authors must pay $500 for each submission — and another $500 if they want the journal to reconsider its decision to reject the paper.

Under “Appeals,” the journal writes:

Continue reading Want to appeal a journal’s rejection? Sure — that’ll be $700

More notices appear for embattled Cornell food researcher

Journals have posted two corrections alongside papers by Brian Wansink, a food researcher whose work has lately come under fire.

One of the corrected papers was among the initial batch that raised eyebrows last year; after Wansink praised the productivity of one of his researchers, critics suggested four papers contained critical flaws. The questions about his work soon extended to other papers, one of which was retracted in April. That month, an internal review by Cornell University announced that Wansink made numerous mistakes, but did not commit misconduct. Wansink has pledged to reanalyze multiple papers.

One paper that was among those initially criticized has received a formal correction notice from the Journal of Product & Brand Management. The notice, which appears behind a paywall, has drawn fire from a regular critic of Wansink’s work, Jordan Anaya, who argues “this correction actually needs a correction, actually several.”

Here’s the notice for “Peak-end pizza: prices delay evaluations of quality:”

Continue reading More notices appear for embattled Cornell food researcher

Are there foxes in Tasmania? Follow the poop

Stephen Sarre, based at the University of Canberra in Australia, has made a career out of collecting and analyzing poop.

It’s a tough job, but someone’s got to do it. Part of his work is designed to answer a multi-million dollar question: Is Tasmania home to foxes, a pest that carries rabies and other diseases and can ravage local wildlife? According to the Australian news outlet ABCthe Tasmanian and Australian governments have spent $50 million (AUD) on hunting foxes on the island since 2001 — even though many have debated whether they are even there.

In 2012, after analyzing thousands of fecal samples, Sarre published a paper in the Journal of Applied Ecology which boldly claimed that “Foxes are now widespread in Tasmania.” But many outside researchers didn’t buy it, and quickly voiced their criticisms of the paper, namely that there may be problems with false positives and the methodology used to analyze the samples. Recently, the journal issued an expression of concern for the paper, citing an ongoing investigation into the allegations.

Here’s the expression of concern (paywalled, tsk tsk):

Continue reading Are there foxes in Tasmania? Follow the poop