Category: wiley

“Sufficiently serious” issues in study prompt company to yank drug approval application in China

The maker of a leading over-the-counter antacid has withdrawn its application for approval of the drug in China because a clinical trial of the product in that country was marred by “major protocol deviations.”

Researchers for the company, Reckitt Benckiser, maker of Gaviscon, had published a report on the study in 2015 in the journal Alimentary Pharmacology & Therapeutics. But the journal has now retracted the article, “Randomised clinical trial: The clinical efficacy and safety of an alginate‐antacid (Gaviscon Double Action) versus placebo, for decreasing upper gastrointestinal symptoms in symptomatic gastroesophageal reflux disease (GERD) in China,” at the behest of the drug maker.

According to the notice: Continue reading “Sufficiently serious” issues in study prompt company to yank drug approval application in China

What should happen to a paper published by Theranos?

Elizabeth Holmes, via Wikimedia

Last December, a group of scientists at a biotech firm published a paper on a “miniaturized, robotic clinical laboratory.” The technique, according to the authors, “would benefit patients and physicians alike.”

Nothing terribly unusual there. But what was — and what caught the eye of a Retraction Watch reader — was the name of the last author: Elizabeth Holmes.

Continue reading What should happen to a paper published by Theranos?

Misconduct probe of once rising star prompts retraction of cat’s meow paper

A group of Australian researchers who studied the cat’s meow as a model for urinary incontinence and other motor-neural issues in people have lost a 2015 paper in the wake of a misconduct investigation.

The target of the inquiry was Hari Subramanian, a former senior research fellow at the Queensland Brain Institute, part of the University of Queensland (UQ). Subramanian was leading studies of incontinence in the elderly, for which he sometimes used nerve stimulators on live rodents and cats. As The Australian reported last September, animal rights activists have objected to his research methods — which sometimes involved sticking probes into the brains of living animals.  

Recently, the school launched an investigation — prompted by an unknown complainant — into the integrity of Subramanian’s data in two articles, including one, now retracted, that appeared in the Journal of Comparative Neurology.  

The case is controversial, to say the least, replete with allegations of unfair attacks. Subramanian’s lawyer told us the journal may be reviewing its decision to retract the paper. (We couldn’t confirm that with the editor.)

Here’s what we’ve found out so far.

Continue reading Misconduct probe of once rising star prompts retraction of cat’s meow paper

Dental journal pulls a dozen papers for recycled images and “unreliable data”

A leading orthodontics journal has retracted 12 papers after determining that they contained either reused images, questionable data or both. Several of the articles involved experiments conducted in dogs — and one person familiar with the case told us that the duplication was an attempt to avoid sacrificing more animals than necessary for the research.  

Although the list of authors on the articles varies, the common denominator is Jose Luis Calvo-Guirado, of the UCAM Universidad Católica San Antonio de Murcia, in Spain. Calvo-Guirado’s title at the institution is director de la Cátedra Internacional de Investigación en Odontología, which Google translates as director of the International Research Chair in Dentistry.  Calvo-Guirado also holds (or has held) a research professorship at SUNY Stony Brook in the Department of Prosthodontics and Digital Medicine, according to his CV.

Calvo-Guirado’s name is on at least 187 entries in PubMed. Of those, 40 appeared in Clinical Oral Implants Research, a Wiley title on whose editorial board the researcher served, according to his CV.  

Continue reading Dental journal pulls a dozen papers for recycled images and “unreliable data”

Sturgeon researcher nets 13 retractions for fake peer review

A fish scientist in Iran has now lost 13 papers about the properties of Sturgeon sperm — try saying that five times fast — and other ichthyological topics over concerns about faked peer review.

The three most recent retractions come from the Journal of Animal Physiology and Animal Nutrition. According to the notice:

Continue reading Sturgeon researcher nets 13 retractions for fake peer review

Author: “The retractions were about bureaucracy, not science”

A researcher has retracted two 2014 papers, after discovering they had not gone through the proper approval process before being submitted.

The papers were part of a collaboration funded by the U.S. National Institutes of Health, which focused on solving protein structures. Adam Godzik, the senior author, told Retraction Watch that all papers had to be approved by a special committee before being submitted to a journal. Given the scale of the collaboration, the committee for the Joint Center for Structural Genomics (JCSG) would assess whether researchers who had made a previous contribution to the work should be added as authors.

Proteins: Structure, Function, and Bioinformatics retracted both papers after Godzik informed the editor in August 2014 that neither article had undergone the required review before being submitted to the journal. Although Wiley agreed to the retractions in an email to Godzik in September 2014,  the papers were only pulled in January—more than three years later. Continue reading Author: “The retractions were about bureaucracy, not science”

“Clear signs of manipulation” in paper co-authored by prominent geneticist

David Latchman

A third paper co-authored by researchers based at a prominent lab whose work has been under investigation on and off for almost three years has been retracted.

According to the notice, the university’s investigation found that a 2008 paper in FEBS Letters contained “clear signs of manipulation” in three figures.

Research from geneticist David Latchman’s group has been dogged by misconduct allegations since late 2013 and subject to two investigations by the University College London (UCL). Continue reading “Clear signs of manipulation” in paper co-authored by prominent geneticist

Why one journal will no longer accept author-suggested reviewers

In a recent editorial, the Journal of Neurochemistry declared it would no longer accept author-suggested reviewers. While other journals have done the same in order to prevent fake reviews, the Journal of Neurochemistry is basing its decision on a different logic. We spoke with editor Jörg Schulz about why he believes relying on reviewers picked by editors helps reduce bias in the peer-review process.

Retraction Watch: What prompted you to compare the outcomes of papers reviewed by experts suggested by authors versus experts selected by editors, or experts the authors “opposed?”

Continue reading Why one journal will no longer accept author-suggested reviewers

Journal retracts paper after discovering lead author forged co-author’s signature

A pharmacy journal has retracted a 2017 cancer paper after determining that the lead author forged her co-author’s signature.

Alain Li Wan Po, editor-in-chief of the Journal of Clinical Pharmacy and Therapeutics, told Retraction Watch that, after discovering the forgery, the journal lost confidence in “the integrity of the whole report,” and decided to retract it:

Our judgment was that if an author is willing to forge a signature, we cannot be sure of the integrity of the whole report and decided on the retraction.

According to Po, the paper’s lead author, Yan Wang, objected to the retraction because “she maintained that the data were accurate.” So the editors retracted the paper without her approval — but with the agreement of the author Jatinder Lamba, whose name was forged.

How did the journal discover the forged signature?

Continue reading Journal retracts paper after discovering lead author forged co-author’s signature

Fracking paper overstated size of methane leak from Marcellus Shale, earning retraction

via Greens-EFA

Last spring, a group of environmental scientists reported an impressive finding: Hydraulic fracturing (better known as fracking) in the Marcellus Shale region of the eastern United States was leaking enough methane to power a city twice the size of Washington, D.C. (We didn’t come up with that comparison, apt though it may be.)

Turns out that wasn’t true. Continue reading Fracking paper overstated size of methane leak from Marcellus Shale, earning retraction