Caught Our Notice: Oops — paper included proofreader’s query

Via Wikimedia

Title: Concise Review: Mesenchymal Stem Cells in Neurodegenerative Diseases

What Caught Our Attention: Everyone makes mistakes — but some are more amusing than others. In one recent correction, the publisher (Wiley) admitted to including a proofreader’s query in the published manuscript. But didn’t say what the query was.

We looked around, and think we found the added notes in the abstract on the PubMed entry (emphasis ours):  Continue reading Caught Our Notice: Oops — paper included proofreader’s query

Caught Our Notice: Concerns about image in 2008 paper prompt editorial notice

Via Wikimedia

Title: Characterization of a novel epigenetically-silenced, growth-suppressive gene, ADAMTS9, and its association with lymph node metastases in nasopharyngeal carcinoma

What caught our attention: One year ago, a PubPeer user suggested an image from a 2008 paper looked similar to one from another paper. After the authors stated their belief in the soundness of the image, without providing the originals, the journal issued only an Expression of Concern for the paper. Some journals have issued retractions for lack of original data, some have issued corrections, and even fewer have published editorial notices. Expressions of concern usually indicate that some type of final resolution will be announced, but in reality, a significant proportion remain unresolved for years. Based on the wording of this notice, it may be around for a while. Continue reading Caught Our Notice: Concerns about image in 2008 paper prompt editorial notice

Boys will be boys: Data error prompts U-turn on study of sex differences in school

The authors of a 2017 paper on emotional and behavioral gaps between boys and girls have retracted the article after discovering a coding error that completely undermined their conclusions.

The revelation prompted the researchers to republish their findings in the same journal, this time with a title that flips the narrative.

The PsychJournal study, first published in March, looked at self-regulation — loosely defined as the ability to get stuff done and keep a lid on it —  in boys and girls in German elementary schools. Although previous studies had found girls might do better on this front, the authors, from the University of Leipzig and New York University’s Abu Dhabi campus, initially found the opposite:

Continue reading Boys will be boys: Data error prompts U-turn on study of sex differences in school

Dispute over author order torpedoes paper on syndrome linked to autism

At least one disgruntled co-author has triggered the retraction of a paper presenting a novel approach to treating a rare, genetically inherited condition.

The paper concerned research on Fragile X syndrome (FXS), characterized by both intellectual and physical abnormalities, which is linked autism. A compound that passed through phase 2 clinical trials in October 2015 appeared to partially treat FXS in mice in the study, published earlier this year.

The journal’s notice says the paper was retracted over a dispute among authors about the order in which they are listed on the paper: Continue reading Dispute over author order torpedoes paper on syndrome linked to autism

Miffed at exclusion from a meta-analysis, researcher writes own “expression of concern”

On June 10, Psycho-Oncology, a journal that publishes research on the “psychological, social, behavioral, and ethical” side of cancer, received a complaint.

In a letter, Ad Kaptein, a researcher at the Leiden University Medical Centre, in the Netherlands, wrote to say that a review and meta-analysis published by the journal that month hadn’t adequately cited the relevant literature in the field, including seven studies co-authored by Kaptein himself. The authors of the original paper say they had considered citing Kaptein’s work but decided against it, for various reasons.

The journal considered Kaptein’s complaint valid enough to publish his letter. But the letter carries the title “Expression of concern” — a term usually reserved for editorial notices issued by the journal to warn readers about some aspects of an article. But in this case, the author supplied the term, not the journal — yet the letter is tagged as an Expression of Concern on PubMed, giving the impression the paper has received a formal editorial notice.

Journal Co-Editor Maggie Watson told Retraction Watch:

Continue reading Miffed at exclusion from a meta-analysis, researcher writes own “expression of concern”

Chemistry journal issues correction longer than original paper

A 2011 chemistry paper required corrections so extensive that the author published the changes as a second, longer paper.

Both papers, published in the Chinese Journal of Chemistry, described the synthesis of a protein molecule with potential therapeutic applications in cancer. But when the paper’s corresponding author Yikang Wu tried to continue the work, he discovered that a substantial part of the 2011 study was incorrect.

The original paper is not marked with any editor’s note, even though the new paper — which is three pages longer than the 2011 version — acknowledges it is a “partial retraction/correction of previous results.” The new paper does appear in the list of “related content” for the 2011 article.

Given the errors, in the 2017 paper, Wu and his co-authors write: Continue reading Chemistry journal issues correction longer than original paper

Two more retractions for former US prof who altered dozens of images

Two journals have retracted papers by a biologist who was recently found guilty of misconduct by his former employer, the University of Colorado Denver, bringing the total to five.

The investigation report by UC Denver, which we obtained earlier this year via a public records request, had recommended one of the two newest retractions, which appears in the journal Hepatology. The other retraction, in the Journal of Immunology, was not flagged by the report — which found, among other conclusions, that Almut Grenz had altered multiple values in research that had already been submitted for peer review.

Here’s the notice for the Journal of Immunology paper:

Continue reading Two more retractions for former US prof who altered dozens of images

Former MD Anderson researcher objects to retraction of his paper

A cell biology journal has retracted a 2016 paper after an investigation revealed that the corresponding author failed to include two co-authors and acknowledge the funding source.

According to the retraction notice, the Journal of Cellular Physiology retracted the paper after the University of Texas, MD Anderson Cancer Center found that last author Jin Wang had omitted two researchers from the list of authors, and had also failed to acknowledge funding from the U.S. National Institutes of Health (NIH).

But Wang tells a different story. Continue reading Former MD Anderson researcher objects to retraction of his paper

Released FDA docs reveal details of agency’s (failed) attempt to retract paper

Earlier this year, a raging controversy regarding a new drug spilled into the pages of a leading medical journal: the head of the U.S. Food and Drug Administration and another official publicly called for the retraction or correction of a peer-reviewed article about the drug. They didn’t get their wish. Now, documents released by the FDA via a lawsuit shed light on the attempt — and show how tricky it can be to correct the official record.

The controversy surrounds the approval of eteplirsen, a drug approved last September to treat Duchenne Muscular Dystrophy, a rare but invariably fatal disease that strikes (mostly) young boys. Eteplirsen was approved over the objections of the FDA team that reviewed the drug, which determined that there was insufficient evidence to approve the drug.

But the controversy didn’t end within the walls of the FDA complex. Ellis Unger, who led the review team, believed that one of the principal studies of the drug, published in the Annals of Neurology, was “misleading” because it was based on “unreliable data.” So in early November, Unger, joined by the then-head of the FDA, Robert Califf, took the extremely rare move of writing to the editor of the journal to “urge that the paper be corrected or retracted….”

According to the documents, the authors of the Annals article did, in fact, agree to correct the article.

On November 9, 2016, Clifford Saper, Annals‘ editor in chief, wrote to Califf and Unger:

Continue reading Released FDA docs reveal details of agency’s (failed) attempt to retract paper

Uni dings schizophrenia studies for problems with informed consent, other flaws

Psychiatry journals have retracted two papers evaluating a schizophrenia drug after a university in Japan flagged issues, such as a lack of written informed consent.

The papers—published in Human Psychopharmacology: Clinical & Experimental in 2012 and Psychiatry and Clinical Neurosciences in 2014—examined the safety and effectiveness of an antipsychotic drug in patients with schizophrenia.

According to the retraction notice in Psychiatry and Clinical Neurosciences, the ethics committee at St. Marianna University School of Medicine in Kawasaki found that “the trial included subjects who did not satisfy inclusion criteria.” For instance, not all patients provided written informed consent. But the university found no evidence for data falsification or fabrication.

A spokesperson for Human Psychopharmacology told us: Continue reading Uni dings schizophrenia studies for problems with informed consent, other flaws