Sebastiani group retracts genetics of aging study from Science

When a group of researchers last year claimed to have found a “genetic signature” to identify people likely to live to 100, they were questioned immediately. Now they’ve retracted the controversial paper —  but continue to stand behind their assertion.

The paper had been the subject of an “Expression of Concern” in November. The retraction notice in this week’s Science: Continue reading Sebastiani group retracts genetics of aging study from Science

Another for Mori: 1999 Infection and Immunity paper pulled

When we first wrote about Naoki Mori last December, one question we had was why Infection and Immunity, the journal that got the ball rolling in this case, wasn’t retracting a 1999 article by the serial manipulator. Well, it has.

The August issue of the journal, a publication of the American Society of Microbiology — which levied a 10-year ban on Mori for his misdeeds — contains the following retraction notice: Continue reading Another for Mori: 1999 Infection and Immunity paper pulled

Carsten Carlberg out at University of Luxembourg

The University of Luxembourg has fired researcher Carsten Carlberg after concluding that his name was a drag on the institution.

Here’s an English  translation of an article about the firing, which many readers were kind enough to forward to us: Continue reading Carsten Carlberg out at University of Luxembourg

University of Louisville investigating work by team under review at Emory

On Tuesday, we reported that Emory University in Atlanta was looking into why a team of former researchers — now at the University of Louisville — had retracted three papers in the Journal of Biological Chemistry (JBC).

Today, we learned that the researchers’ home institution since 2009 is now investigating the work. A spokesperson tells Retraction Watch: Continue reading University of Louisville investigating work by team under review at Emory

German paper on inflammation taken out of Circulation (Research) for data manipulation

Circulation Research, a journal of the American Heart Association (AHA), has retracted a 2009 article from a German group whose first author copped to manipulating data — and got called on it. From the notice: Continue reading German paper on inflammation taken out of Circulation (Research) for data manipulation

Emory looking into circumstances of three new retractions in the JBC

Emory University is looking into why the Journal of Biological Chemistry (JBC) has retracted three papers published by Emory faculty from 2005 to 2007, Retraction Watch has learned. The papers were: Continue reading Emory looking into circumstances of three new retractions in the JBC

So how often does medical consensus turn out to be wrong?

In a quote that has become part of medical school orientations everywhere, David Sackett, often referred to as the “father of evidence-based medicine,” once famously said:

Half of what you’ll learn in medical school will be shown to be either dead wrong or out of date within five years of your graduation; the trouble is that nobody can tell you which half–so the most important thing to learn is how to learn on your own.

Sackett, we are fairly sure, was making an intentionally wild estimate when he said “half.” [See note about these strikethroughs at bottom of post.]  But aA fascinating study out today in the Archives of Internal Medicine gives a clue as to the real figuresuggests that he may have been closer than any of us imagined. Continue reading So how often does medical consensus turn out to be wrong?

Authors retract Nature Medicine cystic fibrosis paper after some results don’t hold up

The authors of a Nature Medicine study published online in September about the behavior of white blood cells in cystic fibrosis have retracted the paper, saying that further experiments suggested the original results were unreliable. According to the notice: Continue reading Authors retract Nature Medicine cystic fibrosis paper after some results don’t hold up

“Representative” image in liver paper leads to retraction

The journal International Immunology has retracted a 2007 article, “Amelioration of hepatic fibrosis via beta-glucosylceramide-mediated immune modulation is associated with altered CD8 and NKT lymphocyte distribution,” by a group of Israeli liver researchers whose manuscript included a composite image that didn’t quite call itself such.

The study, by scientists at Hadassah Medical Center in Jerusalem, purported to show that a soy-derived compound could reduce liver disease in mice. It has been cited 17 times, according to Thomson Scientific’s Web of Knowledge. The journal is published by Oxford and the Japanese Society for Immunology.

From the notice: Continue reading “Representative” image in liver paper leads to retraction

Second retraction by Harvard group studying cannabinoids, this one in JBC

Last week, we reported that a group of Harvard researchers had retracted a paper in Blood for “multiple instances of duplicate (redundant) publication of data, text, and images that are nonessential to the paper.” The retraction notice referred to a paper in the Journal of Biological Chemistry (JBC):

The redundancies are between the above-cited Blood article and the following 12 November 2010 article, published in the Journal of Biological Chemistry (JBC): Jiang S, Zagozdzon R, Jorda MA, et al. Endocannabinoids are expressed in bone marrow stromal niches and play a role in interactions of hematopoietic stem and progenitor cells with the bone marrow microenvironment. J Biol Chem. 2010;285(46):35471-35478.

Today, we learned that the JBC paper has also been retracted. The notice, as we’ve come to expect from the JBC, is unhelpful: Continue reading Second retraction by Harvard group studying cannabinoids, this one in JBC