A Lancet journal has retracted and replaced a 2021 paper on the treatment of pancreatic cancer over an error that prompted an institutional investigation.
The article, “Stereotactic body radiotherapy plus pembrolizumab and trametinib versus stereotactic body radiotherapy plus gemcitabine for locally recurrent pancreatic cancer after surgical resection: an open-label, randomised, controlled, phase 2 trial,” appeared last July in Lancet Oncology and received a significant amount of attention on social media. It has already been cited seven times, according to Clarivate Analytics’ Web of Science.
According to the journal, after publication readers notified the editors about potential problems with the data – in particular, apparent issues with the survival curves in study. In October 2021, the journal published a letter to the editor by a group in Japan detailing the concerns and stating that:
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