Two papers to be retracted after ORI finds misconduct by Boston University cancer researcher

courtesy Nature Publishing Group

The U.S. Department of Health and Human Services’ Office of Research Integrity (ORI) has found that a Boston University cancer researcher made up experiments reported in two papers funded by National Cancer Institute and National Institutes of Health grants. According to the ORI notice:

Sheng Wang, PhD, Boston University School of Medicine Cancer Research Center: Based on the Respondent’s acceptance of ORI’s research misconduct findings, ORI found that Dr. Sheng Wang, who has been an Assistant Professor, Department of Medicine, Boston University School of Medicine Cancer Research Center (BUSM), engaged in research misconduct in research supported by National Cancer Institute (NCI), National Institutes of Health (NIH), grants R01 CA102940 and R01 CA101992.

The two papers were: Continue reading Two papers to be retracted after ORI finds misconduct by Boston University cancer researcher

Marc Hauser resigns from Harvard

Marc Hauser, the Harvard psychology professor who retracted a paper last year following a university investigation, has resigned his post. As the Boston Globe’s Carolyn Johnson, who broke the original Hauser retraction story, reports: Continue reading Marc Hauser resigns from Harvard

University of Louisville investigating work by team under review at Emory

On Tuesday, we reported that Emory University in Atlanta was looking into why a team of former researchers — now at the University of Louisville — had retracted three papers in the Journal of Biological Chemistry (JBC).

Today, we learned that the researchers’ home institution since 2009 is now investigating the work. A spokesperson tells Retraction Watch: Continue reading University of Louisville investigating work by team under review at Emory

Emory looking into circumstances of three new retractions in the JBC

Emory University is looking into why the Journal of Biological Chemistry (JBC) has retracted three papers published by Emory faculty from 2005 to 2007, Retraction Watch has learned. The papers were: Continue reading Emory looking into circumstances of three new retractions in the JBC

Second retraction by Harvard group studying cannabinoids, this one in JBC

Last week, we reported that a group of Harvard researchers had retracted a paper in Blood for “multiple instances of duplicate (redundant) publication of data, text, and images that are nonessential to the paper.” The retraction notice referred to a paper in the Journal of Biological Chemistry (JBC):

The redundancies are between the above-cited Blood article and the following 12 November 2010 article, published in the Journal of Biological Chemistry (JBC): Jiang S, Zagozdzon R, Jorda MA, et al. Endocannabinoids are expressed in bone marrow stromal niches and play a role in interactions of hematopoietic stem and progenitor cells with the bone marrow microenvironment. J Biol Chem. 2010;285(46):35471-35478.

Today, we learned that the JBC paper has also been retracted. The notice, as we’ve come to expect from the JBC, is unhelpful: Continue reading Second retraction by Harvard group studying cannabinoids, this one in JBC

“Nonessential” duplication leads to retraction of Blood cannabinoid paper

The journal Blood has retracted a paper from a group of prestigious Harvard researchers after the article, which appeared in January 2011, was found to have multiple instances of material — text, data and other elements — that had appeared in a previous publication from several of the authors.

The article was titled “Cannabinoid receptor 2 and its agonists mediate hematopoiesis and hematopoietic stem and progenitor cell mobilization.” Its authors included Hava Avraham, a noted cancer researcher, and Jerome Groopman, known for his New Yorker articles about medicine and, scientifically, for his work on cannabinoids and cancer, among other areas.

According to the retraction notice: Continue reading “Nonessential” duplication leads to retraction of Blood cannabinoid paper

Anil Potti resurfaces at South Carolina cancer center

courtesy Duke

Anil Potti, the oncologist who has been forced to retract four papers because of results that could not be reproduced, and resigned last fall from Duke, has a new job. He’s joined the Coastal Cancer Center, an oncology practice with four offices in South Carolina and one in North Carolina.

The Duke Fact Checker was apparently the first to report the news. The Cancer Letter, which has been out front on the Potti story for a year, first reported the news.*

It’s not surprising that Potti’s Coastal Center bio leaves out any mention of his troubled research and the fact that he faked a Rhodes scholarship on a grant application. Investigations into what happened at Duke are ongoing. Continue reading Anil Potti resurfaces at South Carolina cancer center

The Importance of Being Reproducible: Keith Baggerly tells the Anil Potti story

For those Retraction Watch readers who have been following the case of Anil Potti — who has now retracted four papers — Keith Baggerly’s name will likely be familiar. Baggerly is the bioinformatician at M.D. Anderson in Houston who has been publicly questioning, in letters, papers, and The Cancer Letter, work by Potti et. al.

Yesterday, Baggerly gave a keynote at the Council of Science Editors meeting in Baltimore. It was a fascinating — and riveting — walk through how, after a group at M.D. Anderson asked him and his team to evaluate the Potti group’s tools for predicting whether given patients would respond to different chemotherapies, Baggerly’s group unraveled the Potti research.

In his talk, Baggerly demonstrated all of the mislabeling and other easily recognized errors his team found when they sifted through the raw data. And yet there were a number of wince-inducing moments in which Baggerly described the cool reception he had from several journals.

There have been a lot of calls recently that journals should require that authors deposit their data.  There’s none more powerful than when they come at the end of a talk showing how that could have stopped a faulty clinical trial from ever starting.

Baggerly told Retraction Watch he just wants this story to get the widest attention possible, so he was glad to allow us to post his slides. They get appropriately technical, given the crowd, but it’s worth it. You can follow a very unofficial and rough transcript at this Twitter search, since Ivan live-tweeted the talk. Or just click over to the slideshow here.

Data fraud at Emory leads to retractions of three cardiology papers

An investigation by Emory University in Atlanta has led to the retractions of three articles containing falsified data, but the ambiguous wording of the notices leaves us wondering if they are implying more than they state.

Two of the papers appeared in the journal Arteriosclerosis, Thrombosis, and Vascular Biology. The notices in ATVB implicate a researcher named Lian Zuo, who worked in Emory’s division of cardiology.

Here’s one: Continue reading Data fraud at Emory leads to retractions of three cardiology papers

Science publishes replication of Marc Hauser study, says results hold up

There has been some news over the past few weeks about Marc Hauser, the Harvard psychologist found guilty of misconduct by the university last year. First, because Harvard had listed him in a course catalog, The Crimson said that he might be teaching again, following a ban. But that turned out not to be the case, as The Boston Globe reported.

Today, Science lifted the embargo on a paper by Hauser and Justin Wood, now of the University of Southern California, showing that results published in the journal in 2007 — and later questioned — have held up. The abstract: Continue reading Science publishes replication of Marc Hauser study, says results hold up