Trachea surgeon Macchiarini acted “without due care,” but is not guilty of misconduct: Karolinska

Paolo Macchiarini
Paolo Macchiarini

Following an investigation, Karolinska Institutet has found that surgeon and visiting professor Paolo Macchiarini acted in some cases “without due care,” but that his behavior “does not qualify as scientific misconduct.”

Karolinska’s Vice Chancellor has also recommended that Macchiarini submit an unspecified number of corrections “to clarify and rectify the failings that the inquiry has brought to light.”

Macchiarini is most well-known for pioneering the creation of tracheas from cadavers and patients’ own stem cells. However, the glow of his success was diminished somewhat after four Karolinska surgeons filed a complaint, alleging Macchiarini had downplayed the risks of the procedure and not obtained proper consent, among other accusations.

An external review by Bengt Gerdin of Uppsala University concluded in May that Continue reading Trachea surgeon Macchiarini acted “without due care,” but is not guilty of misconduct: Karolinska

Misconduct found in 7 papers by Macchiarini, says English write-up of investigation

Paolo Macchiarini
Paolo Macchiarini

The Karolinska Institutet in Sweden has released an English translation of an external review that found Paolo Macchiarini, a celebrated surgeon who is credited with creating tracheas from cadavers and patients’ own stem cells, committed misconduct in a series of papers describing the work.

You can read the entire report, news of which was first reported by Sciencehere. The investigator, Bengt Gerdin, of Uppsala University, considered a series of allegations about Macchiarini’s papers, and found a number of them lived up to the verdict of misconduct. There were seven affected papers, not six, as was reported last week based on the initial findings (reported in Swedish).

For instance, in a 2014 Nature Communications paper describing the procedure in rats, Gerdin found that the scientists erred when none of the listed authors could assume responsibility for a CT image showing rats with “a smooth and patent oesophagus” (the researcher who took it asked to be left off the author list when he disagreed with how it was being interpreted), among other issues: Continue reading Misconduct found in 7 papers by Macchiarini, says English write-up of investigation

“Super-surgeon” Macchiarini guilty of misconduct, external review finds

Paolo Macchiarini
Paolo Macchiarini

Paolo Macchiarini, the celebrated surgeon whose work has come under scrutiny in Italy and at the Karolinska Institutet in Sweden, committed misconduct in six papers, according to an external reviewer.

Macchiarini is best known for creating tracheas from cadavers and patients’ own stem cells. The findings of the external review, first reported yesterday by SvD Nyheter, were made public last week. They are only available in Swedish thus far, and we have requested a copy from the Karolinska.

External reviewer Bengt Gerdin, of Uppsala University, summarized his findings this way for Retraction WAtch: Continue reading “Super-surgeon” Macchiarini guilty of misconduct, external review finds

“Super-surgeon” Macchiarini not guilty of misconduct, per one Karolinska investigation

Paolo Macchiarini
Paolo Macchiarini

Surgeon Paolo Macchiarini, who is under investigation for allegedly downplaying dangers of an experimental surgery, has been cleared of some misconduct allegations by the Karolinska Institutet in Stockholm.

Macchiarini, a thoracic surgeon, has made headlines for repairing damaged airways using tracheas from cadavers and even synthetic tracheas, both treated with the patients’ own stem cells to assist in the transplant.

In a letter to Vice-Chancellor Anders Hamsten dated last month, KI’s Ethics Council refuted a number of accusations leveled against Macchiarini by Pierre Delaere at KU Leuven in Belgium, who had suggested the surgeon had engaged in scientific misconduct, including fabricating data.

The Ethics Council, however, disagreed:

Continue reading “Super-surgeon” Macchiarini not guilty of misconduct, per one Karolinska investigation

“Conscious fabrication” leads to retraction of diabetes study

diabetcoverDiabetologia has retracted a 2011 meeting abstract from a group in Sweden, indicating that the second author has been found guilty of research misconduct — a charge the scientist denies.

The abstract, “Reduced syntaxin-5 in skeletal muscle of patients with type 2 diabetes is linked to increased diacylglycerol, activation of PKCtheta and impaired insulin signalling,” was presented at the annual meeting of the European Association of the Study of Diabetes. The first author was Kurt Højlund, who now is at the University of Southern Denmark. The second author was Pontus Boström, of the Karolinska Institutet.

According to the notice: Continue reading “Conscious fabrication” leads to retraction of diabetes study

Doing the right thing: Authors retract PNAS paper when new experiments show “conclusion was incorrect”

pnascoverResearchers in Sweden and Australia have retracted a paper in the Proceedings of the National Academy of Sciences (PNAS) after follow-up experiments disproved their conclusions.

Here’s the notice for “Dominant suppression of inflammation by glycan-hydrolyzed IgG,” which is signed by all nine of the paper’s authors: Continue reading Doing the right thing: Authors retract PNAS paper when new experiments show “conclusion was incorrect”

Bitter rheumatology authorship dispute ends in retraction

rbrA 2012 expression of concern prompted by an authorship dispute has been upgraded to a retraction.

As we reported in 2012, Revista Brasiliera de Reumatologia (aka the Brazilian Journal of Rheumatology) issued an expression of concern about “Anticitrullinated peptide antibodies and rheumatoid factor in Sudanese patients with Leishmania donovani infection” after

a claim from one of the authors, questioning the authorship of the corresponding author, and informed that the article was under submission to another journal.

The journal sought the advice of the Committee on Publication Ethics (COPE), and continued its investigation. That investigation is apparently now complete, and this retraction notice is the result: Continue reading Bitter rheumatology authorship dispute ends in retraction

Patient mix-up sinks prenatal supplement paper

This one seems like an honest mistake: a paper on dietary supplements during pregnancy has been retracted based on an error in data recording.

In the BMC Pregnancy & Childbirth paper, “Folic acid supplementation, dietary folate intake during pregnancy and risk for spontaneous preterm delivery: a prospective observational cohort study,” women for whom the researchers had no data on folic acid supplementation were classified as taking no supplements. Despite the error, the authors claim the overall conclusion remains the same: taking folic acid supplements didn’t protect women from preterm deliveries.

Here’s the retraction notice: Continue reading Patient mix-up sinks prenatal supplement paper

Bad spreadsheet merge kills depression paper, quick fix resurrects it

The authors of a paper showing a link between immune response and depression requested a retraction after they realized they’d merged two spreadsheets with mismatching ID codes.

Here’s the notice for “Lower CSF interleukin-6 predicts future depression in a population-based sample of older women followed for 17 years,” retracted in February 2014:

Continue reading Bad spreadsheet merge kills depression paper, quick fix resurrects it

Scholar in Sweden appears to face inquiry for plagiarism retraction

njmrThe Nordic Journal of Migration Research has retracted a 2012 paper by a Swedish researcher who lifted text from another author.

The article, “Swedish Employers and Trade Unions, Varieties of Capitalism and Labour Migration Policies,” was written by Jesper Johansson, of Linnaeus University in Växjö. It’s available as a PDF here, but not on the website of the publisher, De Gruyter — nor is it listed on Johnansson’s own site.

We chose a sentence a random from the abstract:

Continue reading Scholar in Sweden appears to face inquiry for plagiarism retraction