Author of retracted gene editing paper alleges “bullying” by former PI

In the fall of 2015, out-of-work stem cell biologist Mavi Camarasa decided she had waited long enough. It had been three years since she and a colleague were, best they could tell, the first to successfully correct the most common cystic fibrosis mutation in stem cells derived from a patient.

But her former lab director, Daniel Bachiller, had blocked her from writing even a short report, she told Retraction Watch:

He said we are not submitting at this time, wait until [the project is] complete. “Wait, wait,” is the only answer I’d had from him ever.

Though she’d left the Spanish regenerative medicine lab in 2013 to take care of an ailing parent and had mostly been scooped by another group in April of that year, Camarasa thought she still might be able to get something out of the project. She hatched a plan to make him an offer he couldn’t refuse — an already accepted manuscript where all he would have to do is attach his name at the last minute.

But this story didn’t turn out exactly how she’d hoped — and illustrates how the pressure to publish can affect researchers at different levels in the lab.

Continue reading Author of retracted gene editing paper alleges “bullying” by former PI

Rutgers prof announces retraction on his blog

A Rutgers computer scientist is retracting conference proceedings via an unusual channel: his personal blog.

On April 7, Anand Sarwate wrote that he was retracting a mathematical proof from the proceedings from the 2016 IEEE International Conference on Acoustics, Speech, and Signal Processing (ICASSP), after discovering errors that invalidated the result.

He explains in the blog post why the mistake occurred:

Continue reading Rutgers prof announces retraction on his blog

Journal retracts Ohio State CrossFit study at center of lawsuits

The fallout continues for a study conducted at a local CrossFit gym by researchers at The Ohio State University. First it was corrected, now it’s been retracted, and it continues to be the basis of litigation against both the authors and the publisher.

Editors at the Journal of Strength and Conditioning Research have decided to pull the 2013 study after learning that the research protocol had not been approved by Ohio State’s institutional review board (IRB).

Over the past few years, the study has spawned several lawsuits, including a defamation suit brought by gym owner Mitch Potterf against Ohio State that landed him a six-figure settlement, as well as an ongoing suit by Potterf against the National Strength and Conditioning Association (NSCA, which publishes the journal). The CrossFit brand has also sued the NSCA. [See update at end of post for more on that case.]

An NSCA statement issued May 30 describes what happened: Continue reading Journal retracts Ohio State CrossFit study at center of lawsuits

Would-be Johns Hopkins whistleblower loses appeal in case involving Nature retraction

A former researcher at Johns Hopkins who voiced concerns about a now-retracted paper in Nature has lost another bid for whistleblower protection.

Daniel Yuan, a longtime statistician for former Hopkins yeast geneticist Jef Boeke, was dismissed in 2011, after he’d spent years raising concerns about research coming out of the lab. Yuan’s criticisms, which continued after he stopped working for Boeke, peaked in 2012 after Boeke and former labmate Yu-li Lin published paper in Nature. Later that year, Lin was found dead in his lab, a suspected suicide. In 2013, the paper was retracted, citing an inability to reproduce the main conclusions. 

Since 2013, Yuan has pursued a wrongful termination lawsuit, claiming that federal regulations surrounding scientific misconduct afforded him protection from retaliation.

In late March, Maryland’s highest court ruled against Yuan, saying that those misconduct regulations are “too vague” to offer cover to employees claiming whistleblower protection. According to lawyers we consulted, the decision could make it harder for would-be whistleblowers to fight retaliation, while also giving institutions more leeway to handle these issues on their own.

Continue reading Would-be Johns Hopkins whistleblower loses appeal in case involving Nature retraction

Reuters removes story on gender confirmation surgery because firm mistakenly released data

Reuters has removed a story about gender confirmation surgery, saying it included problematic data.

The public relations firm representing the American Society of Plastic Surgeons (ASPS) — which generated the data in the report  — took responsibility, saying it supplied Reuters with data the ASPS did not want released.

Yesterday, Reuters pulled its version of a widely-reported story about an increase in such surgeries in the U.S. (Later, it pulled the withdrawal notice as well, only to make it reappear at a different URL.)

The story, originally posted just after midnight yesterday, reported a 19 percent increase in those procedures from 2015 to 2016, based on data provided the American Society of Plastic Surgeons (ASPS). Around 1 pm US Eastern time that day, Reuters put up a withdrawal notice in place of the original story:

Continue reading Reuters removes story on gender confirmation surgery because firm mistakenly released data

Ex-PhD candidate sues advisor, school: Colorado prof “poisoned the well” after research dispute

A former University of Colorado Boulder graduate student is suing his ex-advisor for defamation after being shooed out midway through his doctoral program.

Robert Roscow says he had to leave CU Boulder’s department of Ecology and Evolutionary Biology (EBIO) in the fall of 2016 with only a master’s degree after fish evolution researcher David Stock dropped him as a student. Their relationship deteriorated following a dispute about whether another student should perform experiments Roscow considered to be essential to his dissertation.

Once dropped, Roscow was offered the chance to find another advisor, but never did. In his complaint, filed April 25 in Boulder County District Court, Roscow claims he has evidence that Stock “poisoned the well” by badmouthing him in email and in person to other professors, ultimately preventing Roscow from completing his degree.

As first reported by BusinessDen, Roscow is also suing CU Boulder for a breach of contract and for failing to “provide [him] with the reasonable opportunity to pursue his PhD,” among other allegations. 

CU Boulder declined to elaborate on the case. Chief Spokesperson Ryan Huff told us:

Continue reading Ex-PhD candidate sues advisor, school: Colorado prof “poisoned the well” after research dispute

Could bogus scientific results be considered false advertising?

Could a scientific paper ever be considered an advertisement?

That was the question posed to a Tokyo court, in a criminal case where prosecutors argued — at the behest of Japan’s ministry of health — that a peer-reviewed paper containing faked data should be considered “fraudulent or exaggerated advertising” under that country’s laws.

In that case, however, the argument didn’t work. In March, the court decided that a fraudulent paper was not false advertising, allowing a pharmaceutical researcher at a Novartis subsidiary to escape jail time. The decision also cleared Novartis of charges and helped the company avoid a ¥4 million ($35,373 USD) fine.

According to an article in The Japan Times, the presiding judge Yasuo Tsujikawa said:

Continue reading Could bogus scientific results be considered false advertising?

“Dramatic impact:” Authors misread breast cancer treatment database, retract paper

A journal has retracted a 2016 study on the use of radiation by breast cancer patients after the authors misinterpreted what was reported in a national cancer database.

Correcting for the error, according to the retraction notice, had a “dramatic impact on the original article data and conclusions.”

Quyen Chu, a surgeon at Louisiana State University Health Shreveport, told us that the problem appears to stem from a misunderstanding about the US National Cancer Database (NCDB). After the paper was published, the NCDB pointed out to Chu that a key data point had not been reliably or consistently collected during the timeframe relevant to the study. The database’s user’s manual says essentially the same thing; Chu said he and his authors read it, but misunderstood it.

The original Journal of the American College of Surgeons study looked at whether a 2004 National Comprehensive Cancer Network treatment guideline — which suggested some patients could avoid radiation on top of surgery and hormone therapy — led to an actual decrease in radiation therapy. But the error forced the authors to drop tens of thousands of patients treated before 2004, which had a severe impact on their ability to draw conclusions.

Chu told us:

Continue reading “Dramatic impact:” Authors misread breast cancer treatment database, retract paper

Former UCLA vice-chancellor loses cancer paper for image manipulation

The former vice chancellor for research at the University of California, Los Angeles, has retracted a 2012 paper after an internal investigation found evidence of image manipulation.

The journal Molecular Cancer Therapeutics received a letter about the problems with the paper from the UCLA Research Integrity Officer, and a retraction request from last author James Economou, also the chief of surgical oncology.

According to the notice, the paper duplicated images from a 2011 paper also by first author Ali Jazirehi, based at UCLA. This is Jazirehi’s second retraction.

Here’s more from the notice:

Continue reading Former UCLA vice-chancellor loses cancer paper for image manipulation

Ecologist loses appeal for whistleblower protection

A top federal U.S. court has confirmed a decision by the National Science Foundation (NSF) to deny federal whistleblower protection to an ecologist who was fired after accusing a colleague of fraud.

After initially forcing NSF to more clearly explain its decision, the Denver-based U.S. Court of Appeals for the 10th Circuit has agreed with the conclusions of NSF’s updated investigation, denying former Kansas State University researcher Joseph Craine’s appeal.

Attorney Paul Thaler, who has handled cases involving scientific misconduct (but was not involved with this one), told Retraction Watch that the latest decision appears to be the end of a cautionary tale of how not to report misconduct.

Continue reading Ecologist loses appeal for whistleblower protection