Retraction Watch

Tracking retractions as a window into the scientific process

Archive for the ‘genetics retractions’ Category

Authors retract PNAS brain genetics paper for statistical issues

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pnas 1113The authors of a paper on brain genetics published online in June in the Proceedings of the National Academy of Sciences (PNAS) are retracting it for “a potential confound relating to statistical inference.”

Here’s the notice for “Identification of gene ontologies linked to prefrontal–hippocampal functional coupling in the human brain:” Read the rest of this entry »

UT-Southwestern cancer research group notches ninth retraction

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lung cancerA research team at the University of Texas-Southwestern that has retracted eight papers for image manipulation has retracted another, this one in Lung Cancer.

Here’s the notice for “Aberrant methylation of Reprimo in lung cancer,” published by Adi Gazdar’s group: Read the rest of this entry »

Incorrect analysis leads to Nature’s sixth retraction in 2014

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nature 714In what seems to be an example of researchers swiftly and transparently correcting the literature, and acknowledging errors, a pair of scientists have retracted a 2013 paper from Nature.

Here’s the retraction notice for “Genomic organization of human transcription initiation complexes,” by Bryan Venters and Frank Pugh: Read the rest of this entry »

Geneticist retracting four papers for “significant problems”

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jbc 620Benjamin Barré, a genetics researcher who recently set up his own group at the University of Angers, is retracting four papers he worked on as a graduate student and postdoc.

Neil Perkins, in whose lab Barré was a postdoc, and Olivier Coqueret, in whose lab he did his PhD, tell Retraction Watch: Read the rest of this entry »

Cancer genetics group retracts three papers for “inappropriate presentation of data”

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jbc 620A group of cancer genetics researchers in Italy and the U.S. has retracted three papers in the Journal of Biological Chemistry (JBC) after it became aware they had duplicated some bands in their figures.

Here are the three papers: Read the rest of this entry »

De-coli: Plagiarism leads to retraction of highly cited recombinant protein paper

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appliedmicrobioThe authors of a 2005 article on E. coli in Applied Microbiology and Biotechnology have lost the paper because they recombined it from previous work.

The article, titled “Strategies for efficient production of heterologous proteins in Escherichia coli,” came from a pair of biochemical engineers from the Indian Institute of Technology-Delhi, in New Delhi, India.

According to the abstract: Read the rest of this entry »

Science retracts two papers for image manipulation

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science 2014Science has retracted two papers by Frank Sauer, of the University of California, Riverside, after the university found evidence of serious image manipulation.

Here’s the notice, signed by Science editor-in-chief Marcia McNutt: Read the rest of this entry »

Forged authorship sinks melanoma paper

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ijbcbThe International Journal of Biochemistry & Cell Biology has retracted a 2013 paper by a group from China after learning that only the first author knew about the article.

The paper was titled “Construction of circular miRNA sponges targeting miR-21 or miR-221 and demonstration of their excellent anticancer effects on malignant melanoma cells,” and it was led by Yuchen Liu. Liu’s affiliations include the Institute of Dermatology and Department of Dermatology at No. 1 Hospital, part of Anhui Medical University, and the State Key Laboratory Incubation Base of Dermatology for the Ministry of National Science and Technology.

Here’s the retraction notice:
Read the rest of this entry »

Former Mount Sinai postdoc faked gene therapy data: ORI

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ori logoA former postdoc at the Mount Sinai School of Medicine in New York faked data in four published papers, one submitted manuscript, and four NIH grant applications, according to new findings by the Office of Research Integrity.

We reported on six retractions from Savio Woo’s Mount Sinai lab in 2010, from the Proceedings of the National Academy of Sciences (PNAS), the Journal of the National Cancer Institute, and two each from Human Gene Therapy and Molecular Therapy. The PNAS paper, as we noted then:

claimed to have discovered a possible cure for phenylketonuria, or PKU, in mice—a finding that was cited more than 30 times and trumpeted in the media.

At the time, Mount Sinai said that two of the lab’s postdocs had been dismissed for misconduct. Now, more than three and a half years later, the ORI reports that a former postdoc in that lab, Li Chen: Read the rest of this entry »

Lack of citation prompts correction in Nature journal

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nature communicationsIt’s not unusual to hear authors bemoan the fact that a new paper doesn’t cite their work that set the stage for a scientific advance. “The journal limited me to [a seemingly abitrary number of] references,” authors sometimes shrug, with or without apology. This week, however, we found a case of that which seems to have been resolved to everyone’s satisfaction.

The authors of a September 2013 article in Nature Communications have issued a correction for the piece, which failed to cite the source of a key step in their experiment.

The article, “Val66Met polymorphism of BDNF alters prodomain structure to induce neuronal growth cone retraction,” came from the lab of William “Clay” Bracken, a biochemist at Weill Cornell Medical College. According to the abstract: Read the rest of this entry »