Archive for the ‘genetics retractions’ Category
Following an investigation into research misconduct, the Journal of Clinical Investigation has retracted a cancer genetics paper from a laboratory at the National Institutes of Health due to “data falsification and fabrication” of four figures and a table in the paper.
The paper, “FOXO3 programs tumor-associated DCs to become tolerogenic in human and murine prostate cancer,” describes an overexpressed gene in mouse prostate cancers that appears to suppress immune system cells.
The journal retracted the paper following an investigation into author Stephanie K. Watkins, then a postdoctoral fellow at the National Cancer Institute. According to a NIH press release released about the study in March 2011, the work “has led to the submission of a patent application by the NIH on behalf of Hurwitz and Watkins to target FOXO3 as a way to boost immune responses in cancer and to silence excessive immune responses in autoimmune diseases.” We found an NIH record of the patent application, but no record of an approved patent at the United States Patent and Trademark Office under either Hurwitz or Watkins’ names.
Genetics and Molecular Research, an online-only journal, has retracted two articles about gastric cancer by a group of Iranian researchers who appear to have put their own names on other people’s data.
Both articles were published in 2014. One was titled “Absolute quantification of free tumor cells in the peripheral blood of gastric cancer patients;” the other, “ZNF797 plays an oncogenic role in gastric cancer.” The list of authors on the two papers isn’t identical, but both papers share a few in common, including the same two last authors: F. Ghasemvand and S. Heidari-Keshel.
It turns out, Saeed Heidari-keshel wasn’t down with other people’s data, and alerted the journal to the problem.
We keep a list of best euphemisms for plagiarism, and this one is right up there.
What’s in a name?
Well, if it’s the same name as a treatment with nearly $1 billion in sales per year in the U.S., a retraction.
A “mind numbingly boring one,” that is.
Here’s the Twin Research and Human Genetics notice for “EpiPen: An R Package to Investigate Two-Locus Epistatic Models”: Read the rest of this entry »
The authors of a paper on brain genetics published online in June in the Proceedings of the National Academy of Sciences (PNAS) are retracting it for “a potential confound relating to statistical inference.”
Here’s the notice for “Identification of gene ontologies linked to prefrontal–hippocampal functional coupling in the human brain:” Read the rest of this entry »
A research team at the University of Texas-Southwestern that has retracted eight papers for image manipulation has retracted another, this one in Lung Cancer.
A group of cancer genetics researchers in Italy and the U.S. has retracted three papers in the Journal of Biological Chemistry (JBC) after it became aware they had duplicated some bands in their figures.
Here are the three papers: Read the rest of this entry »
The article, titled “Strategies for efficient production of heterologous proteins in Escherichia coli,” came from a pair of biochemical engineers from the Indian Institute of Technology-Delhi, in New Delhi, India.