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Retraction Watch

Tracking retractions as a window into the scientific process

Archive for the ‘lack of IRB approval’ Category

Retraction record broken, again: University report should up Fujii total to 183

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a&amisconductcoverKeeping up with the various investigations into the activities of Yoshitaka Fujii — the assumed record holder for retractions by a single author, with 172 likely — can be a challenge. Between the journals pulling his papers and the institutions looking into his misconduct, it’s hard to keep everything straight.

But we have a new report, from a past employer, that makes for interesting reading and helps tie up some loose ends. The document is from Tsukuba University, where Fujii worked more than a decade ago when questions about the propriety of his findings first surfaced. Read the rest of this entry »

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Two Moriguchi stem cell papers being retracted

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It was, as Nature News wrote last month, a story that “seemed too good to be true:”

Stem-cell transplant claims debunked

Transplant of induced pluripotent stem cells to treat heart failure probably never happened

Hisashi Moriguchi, a visiting researcher at the University of Tokyo, had claimed a result that would have put him years ahead of researchers toiling in stem cell research. But the claims were met with a great deal of doubt — to say the least — and the story began to unravel when Harvard, where Moriguchi said he’d done the work, denied it had ever taken place.

And as expected, the retractions have now started. Today, a Nature Publishing Group journal said they would be retracting two papers, “A therapeutic method for the direct reprogramming of human liver cancer cells with only chemicals” and “Successful cryopreservation of human ovarian cortex tissues using supercooling.” The notices for the Scientific Reports papers will both say the same thing: Read the rest of this entry »

PLoS ONE retracts paper on treatment of tissue disease for lack of ethical approval, erroneous data

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PLOS ONE has retracted an article it published earlier this year by a group from Australia who failed to receive adequate ethics approval for their study.

The paper, “Late Complications of Clinical Clostridium Histolyticum Collagenase Use in Dupuytren’s Disease,” came from Warren M. Rozen, Yasith Edirisinghe and John Crock (sorry, irony machine not working today). Dupuytren’s causes thickening of the fascia in the hands and often requires surgery.  In 2011 the FDA approved a treatment for the ailment that involves injections of an enzyme — Clostridium Histolyticum Collagenase, or CHC — into the affected area.

The Aussie article looked at the effects of CHC injections in 12 patients over one year, finding that two of the patients suffered Read the rest of this entry »

Another odd retraction for alcohol researcher, this time for lack of animal research committee approval

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The journal Neuroscience has retracted a 2011 paper by an alcohol researcher from the United Arab Emirates, who apparently conducted some mouse studies without the blessing of his institution’s animal ethics officials. At least, that’s what the retraction notice would have us believe.

The paper in question, “The pre-synaptic metabotropic glutamate receptor 7 “mGluR7” is a critical modulator of ethanol sensitivity in mice,” by Amine Bahi, was published in December 2011 and cited three times (twice by the author), according to Thomson Scientific’s Web of Knowledge. But as the notice explains:

Read the rest of this entry »

Another retraction from chiropractic researchers for lack of ethics approval

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Chiropractic & Manual Therapies — formerly known as Chiropractic & Osteopathy — has retracted a 2010 paper by a team of Australian researchers who failed to obtain institutional review board (IRB) approval for their studies.

As the notice for “A descriptive study of a manual therapy intervention within a randomised controlled trial for hamstring and lower limb injury prevention” explains: Read the rest of this entry »

Hip, hip, hooray! Hip journal retracts paper that had, well, everything wrong with it

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Sometimes, you just gotta retract.

Here’s the retraction notice for “Outcome of short proximal femoral nail antirotation and dynamic hip screw for fixation of unstable trochanteric fractures. A randomised prospective comparative trial,” originally published in Hip International in 2011 by a group of researchers at the All India Institute of Medical Sciences in New Delhi: Read the rest of this entry »

Anesthesia journal retracts paper from Estonian researchers in wake of legal inquiry

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Acta Anaesthesiologica Scandinavica has retracted a 2008 paper by a group of Estonian researchers who appear to have wound up in legal jeopardy for misrepresenting their work.

Here’s the notice: Read the rest of this entry »

Boldt inquiry concludes: False findings in at least 10 studies, but no harm to patients

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Ludwigshafen Hospital, via Wikimedia http://bit.ly/Qnt9wS

It has been a while since we heard about Joachim Boldt, the German anesthesiologist whose 90-odd retractions briefly put him at the top of the heap until Yoshitaka Fujii kicked him off earlier this year.

Now, Boldt’s former institution, the Klinikum Ludwigshafen, has released a report on its investigation into the disgraced critical care expert, and the results aren’t pretty. Here’s a press release about the report, in its entirety: Read the rest of this entry »

Cancer journal pulls deeply flawed meeting abstract on breast surgery

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The European Journal of Surgical Oncology has retracted a meeting abstract that evidently was never meant to be.

The study, by researchers at Queen Elizabeth Hospital and Good Hope Hospital, both in Birmingham, England, was to be presented at this year’s annual meeting of the Association of Breast Surgery and purported to compare rates of patient satisfaction among women who underwent two kinds of breast reconstruction, TRAM — transverse rectus abdominis myocutaneous  — flap and DIEP (short for deep inferior epigastric perforators) flap.

But according to the notice: Read the rest of this entry »

Does anesthesiology have a problem? Final version of report suggests Fujii will take retraction record, with 172

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Japanese investigators have concluded that Yoshitaka Fujii, an expert in postoperative nausea and vomiting whose findings drew scrutiny in 2000 but who continued to publish prolifically for a decade after, fabricated his results in at least 172 published studies.

That number nearly doubles that of the current unofficial retraction record holder, Joachim Boldt.

An inquiry by the Japanese Society of Anesthesiologists (JSA) has determined that Fujii, who was fired in February from his post at Toho University, falsified data in 172 of 212 papers published between 1993 and 2011. Investigators said they found no evidence of fraud in three of the papers, but could not determine whether the results reported in the remaining 37 were reliable.

Of the 172 bogus studies, 126 involved randomized controlled trials. Investigators believe this was not a coincidence: Read the rest of this entry »

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