Retraction Watch

Tracking retractions as a window into the scientific process

Archive for the ‘infection and immunity (journal)’ Category

“Evidence of data duplication” infects lung inflammation paper from Harvard and Yale

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IAIA team of Harvard and Yale biologists have retracted an Infection and Immunity paper due to data duplication.

After the duplication came to light, the erroneous figures were corrected using original data, but the results affected “some of the manuscript’s conclusions.” An ethics panel subsequently recommended retraction, according to the journal, and the authors agreed.

The paper, “NOD2 Signaling Contributes to Host Defense in the Lungs against Escherichia coli Infection,” analyzed the role of the gene NOD2 in the lung inflammatory response against the bacteria Escherichia coli. It has been cited by 15 other papers, according to Thomson Scientific’s Web of Knowledge.

Figure 2B of the paper was previously corrected in 2012, but the retraction is for data duplication in figures 5F and 6A. Here’s the full retraction note: Read the rest of this entry »

Another “first author has accepted responsibility” retraction from immunity journal

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IAIScientists have pulled their 2013 Infection and Immunity paper after a reader noticed duplicated data in three figures, and the first author was “unable to provide the original data used to construct the figures,” according to the journal’s editor-in-chief.

According to the retraction note, “the first author has accepted responsibility for these anomalies” — similar to another recent retraction from the same journal, also due to image duplication reported by a reader (apparently the journal has one or more careful readers).

The paper, “Pseudomonas aeruginosa Outer Membrane Vesicles Modulate Host Immune Responses by Targeting the Toll-Like Receptor 4 Signaling Pathway,” concerns the role of outer membrane vesicles excreted by the bacteria to incite an inflammatory response in mice. It was written by authors at the University of North Dakota, Sichuan University in China, and the University of Chicago, and has been cited six times, according to Thomson Scientific’s Web of Knowledge.

Here’s the complete retraction note:

Read the rest of this entry »

“The first author assumes all responsibility:” Malaria vaccine article retracted for image manipulation

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InfectAndImmunAuthors of a 2012 article in Infection and Immunity investigating a malaria vaccine strategy are retracting it because it “contains several images that do not accurately reflect the experimental data.”

The paper, “Fine Specificity of Plasmodium vivax Duffy Binding Protein Binding Engagement of the Duffy Antigen on Human Erythrocytes,” has been cited 9 times, according to Thomson Scientific’s Web of Knowledge.

The retraction notice places the blame for the image shenanigans squarely on the first author, Asim Siddiqui, who is currently listed on LinkedIn as a faculty member at the College of Applied Medicine at King Saud University in Saudi Arabia.

Here’s the notice: Read the rest of this entry »

“Not faithful” figures kill apoptosis paper

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iaicoverA paper on apoptosis in mice has been retracted by Infection and Immunity after a reader tipped them off that several figures were “not faithful representations of the original data.”

When the journal, published by the American Society for Microbiology (ASM), contacted the authors at Anhui Medical University in Hefei, China, they claimed they couldn’t provide the experimental data thanks to “damage to a personal computer,” said Ferric Fang, editor of the journal and a member of the board of directors of the Center for Scientific Integrity, Retraction Watch’s parent organization. Seven figures in total were compromised, including several that were duplicated throughout the article.

Here’s the notice for “Reactive Oxygen Species-Triggered Trophoblast Apoptosis Is Initiated by Endoplasmic Reticulum Stress via Activation of Caspase-12, CHOP, and the JNK Pathway in Toxoplasma gondii Infection in Mice”: Read the rest of this entry »

Plague paper partially retracted

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iandi213coverPartial retractions — as opposed corrections or the full monty —  are unusual events in scientific publishing. But they appear to come in twos.

The journal Infection and Immunity, the work of whose editor, Ferric Fang, is much admired by this blog, has a fascinating example of the breed in its February issue.

The article in question, by a group from the University of Kentucky in Lexington led by Susan Straley, appeared online in 2007. It was titled “yadBC of Yersinia pestis, a New Virulence Determinant for Bubonic Plague,” and, as the words suggest, involved a gene marker for the virulence of plague. Or so it initially seemed.

But according to the partial retraction, the researchers are walking back one of their main claims. Consider: Read the rest of this entry »

Written by amarcus41

January 22nd, 2013 at 12:00 pm

ORI findings lead to two retractions — nearly 17 years later

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Well, it only took 17 years.

As two retraction notices in the September 15 issue of the Journal of Immunology note:

On October 19, 1995, the Office of Research Integrity at the National Institutes of Health found that Weishu Y. Weiser, Ph.D., formerly of the Harvard Medical School at Brigham and Women’s Hospital, committed scientific misconduct by falsifying data in biomedical research supported by two Public Health Service grants. As a result, she agreed to submit a letter to The Journal of Immunology to retract this article. The offices of The Journal of Immunology have no record of receiving such a letter and hence the article is now being retracted.

The retractions, for “Recombinant Migration Inhibitory Factor Induces Nitric Oxide Synthase in Murine Macrophages” and “Human Recombinant Migration Inhibitory Factor Activates Human Macrophages to Kill Leishmania donovani,” both say the same thing.

“Recombinant Migration Inhibitory Factor Induces Nitric Oxide Synthase in Murine Macrophages” has been  cited 66 times, according to Thomson Scientific’s Web of Knowledge — 40 of those times since the ORI’s report was released. The numbers for the Leishmania paper are almost identical: Read the rest of this entry »

Another for Mori: 1999 Infection and Immunity paper pulled

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When we first wrote about Naoki Mori last December, one question we had was why Infection and Immunity, the journal that got the ball rolling in this case, wasn’t retracting a 1999 article by the serial manipulator. Well, it has.

The August issue of the journal, a publication of the American Society of Microbiology — which levied a 10-year ban on Mori for his misdeeds — contains the following retraction notice: Read the rest of this entry »

Japanese virologist hit with publishing ban after widespread data manipulation

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A leading Japanese virologist has received a 10-year publishing ban from the American Society of Microbiology after many of his published articles were found to have evidence of data manipulation.

In its January 2011 issue, Infection and Immunity, an ASM title, is retracting five articles by the researcher, Naoki Mori, of the University of Ryukyus in Okinawa. The articles, published between 2000 and 2009, involve work on Helicobacter pylori which Nori conducted with co-authors from the United States and elsewhere. Some of the studies listed co-authors from drug companies, including Merck and Boehringer Ingelheim, although it’s not clear whether the companies helped support any of the research.

Despite the impending holidays, Ferric Fang, editor of Infection and Immunity, graciously and quickly replied to our request for comment yesterday (as he has before, about another paper in Nature involving fraud): Read the rest of this entry »


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