Archive for the ‘joachim boldt retractions’ Category
Justus Liebig University in Germany has been investigating concerns that Joachim Boldt, number two on the Retraction Watch Leaderboard and now up to 92 retractions, may have “manipulated” more data than previously believed.
Until now, the vast majority of Boldt’s retractions were thought to have involved inadequate ethics approval. However, new retraction notices for Boldt’s research suggest that there’s evidence the researcher also engaged in significant data manipulation.
The first retraction from the university investigation emerged last year. Two of three new notices cite the investigation specifically, and an informant at the university told us that there are more retractions to come.
Here are the retracted papers that are freshly on the record, starting with an August retraction for a 1991 Anesthesiology paper (cited 37 times, according to Thomson Scientific’s Web of Knowledge):
Update, 4 p.m. EST, 10/29/14: As a commenter points out, we didn’t quite get this one right. The Boldt paper that has been retracted was not previously retracted for lack of IRB approval. Rather, it was a heretofore unretracted article, from 1996, which German investigators have determined contained faked data. We’ve made edits below using strikethroughs, and have changed the headline to better reflect the content. We apologize for the errors.
We’ve commented before on the fact that we’ve noticed there’s often more to retractions whose stated reason is lack of institutional review board (IRB) approval. We can understand editors’ inclination to act as quickly as possible to issue a retraction, the scientific publishing equivalent of jailing Al Capone for tax evasion. But we appreciate it even more when said editors return to the scene of the crime, as it were, when new important details come out.
Case in point: Anesthesia & Analgesia has amended its retraction of a
2009 1996 study by Joachim Boldt — who with nearly 90 retractions once held the record in that department — based on findings that the data in that paper were fabricated.
The article was titled
“Cardiopulmonary bypass priming using a high dose of a balanced hydroxyethyl starch versus an albumin-based priming strategy,” “The effects of albumin versus hydroxyethyl starch solution on cardiorespiratory and circulatory variables in critically ill patient.” had previously been retracted because Boldt had failed to obtain adequate ethics approval for the research. But now comes this, According to the retraction notice from editor in chief Steven Shafer: Read the rest of this entry »
Well, Boldt has another retraction, although he’d need to double his tally (which is in the range of 90) to match Fujii’s “impressive” haul.
The new paper is, well, old, having been published in 1996, some 14 years before Boldt’s tribulations began. The article was titled “Influence of different volume therapy regimens on regulators of the circulation in the critically ill.” It appeared in the British Journal of Anaesthesia, and has been cited 45 times, according to Thomson Scientific’s Web of Knowledge.
The paper, “Analysis and Implications of Retraction Period and Coauthorship of Fraudulent Publications,” by Jong Yong Abdiel Foo and Xin Ji Alan Tan, of Ngee Ann Polytechnic in Singapore, appeared online last week in Accountability in Research: Policies and Quality Assurance.
The authors write that Read the rest of this entry »
That’s what Nadia Elia, Liz Wager, and Martin Tramer reported here Sunday in an abstract at the Seventh International Congress on Peer Review and Biomedical Publication. Elia and Tramer are editors at the European Journal of Anaesthesiology, while Wager is former chair of the Committee on Publication Ethics (COPE).
As of January 2013, nine of the papers hadn’t been retracted, Tramer said, while only five — all in one journal — had completely followed COPE guidelines, with adequate retraction notices, made freely available, along with PDFs properly marked “Retracted.” From the abstract (see page 18): Read the rest of this entry »
If you wanted to minimize the real-life effects of misconduct, you might note that some of the retractions we cover are in tiny obscure journals hardly anyone reads. But a new meta-analysis and editorial in JAMA today suggests — as a study by Grant Steen did a few years ago — that the risk of patient harm due to scientific misconduct is not just theoretical.
As the editorialists note, hydroxyethyl starches (HES) are “synthetic fluid products used commonly in clinical practice worldwide:”
Synthetic colloids received market approval in the 1960s without evaluation of their efficacy and safety in large phase 3 clinical trials. Subsequent studies reported mixed evidence on their benefits and harms.
There has been controversy over the use of HES for decades, with the most recent high-level review showing “no significant mortality increase.” But one of the reasons for that review — by the prestigious Cochrane Collaboration — was to see if the dozens of now-retracted studies by Joachim Boldt Read the rest of this entry »
It has been a while since we heard about Joachim Boldt, the German anesthesiologist whose 90-odd retractions briefly put him at the top of the heap until Yoshitaka Fujii kicked him off earlier this year.
Now, Boldt’s former institution, the Klinikum Ludwigshafen, has released a report on its investigation into the disgraced critical care expert, and the results aren’t pretty. Here’s a press release about the report, in its entirety: Read the rest of this entry »
The European Journal of Anaesthesiology has retracted a paper, “Supplemental oxygen reduces serotonin levels in plasma and platelets during colorectal surgery and reduces postoperative nausea and vomiting,” from Boldt’s former colleagues at the Klinikum Ludwigshafen after determining that the authors were trying to hide their association with the disgraced anesthesiologist.
As the news of Joachim Boldt’s staggering number of retractions leaps from Retraction Watch into the mainstream press, the consortium of journal editors retracting his studies has backtracked ever so slightly, announcing today that one of the 89 studies for which the German anesthesiologist lacked ethics approval in fact had such sanction.
According to the now-16 (Updated 3/7/11, as it is up from 11 several days ago) editors, LÄK-RLP, the German body investigating the ethics component of the Boldt case: Read the rest of this entry »
As we reported the other day, a group of anesthesia journals was on the verge of revealing a list of 89 articles by Joachim Boldt that would require retraction because the German researcher had failed to receive proper approval from ethics officials for his studies. Today, the coalition issued a letter making the retractions official.
The 89 papers join an earlier retraction in October.
Of note: Read the rest of this entry »