Category: basic life sciences retractions

“Nonessential” duplication leads to retraction of Blood cannabinoid paper

The journal Blood has retracted a paper from a group of prestigious Harvard researchers after the article, which appeared in January 2011, was found to have multiple instances of material — text, data and other elements — that had appeared in a previous publication from several of the authors.

The article was titled “Cannabinoid receptor 2 and its agonists mediate hematopoiesis and hematopoietic stem and progenitor cell mobilization.” Its authors included Hava Avraham, a noted cancer researcher, and Jerome Groopman, known for his New Yorker articles about medicine and, scientifically, for his work on cannabinoids and cancer, among other areas.

According to the retraction notice: Continue reading “Nonessential” duplication leads to retraction of Blood cannabinoid paper

Penkowa Journal of Physiology Expression of Concern turns into a retraction

We’ve been trying to follow the complicated case of Milena Penkowa, who resigned her post at the University of Copenhagen in December amidst allegations that she had committed scientific misconduct and misused grant money. Today, we learned that one of the three papers that Penkowa had coauthored and were subject to Expressions of Concern has been retracted. Here’s the notice: Continue reading Penkowa Journal of Physiology Expression of Concern turns into a retraction

The way science should work: A swift, clearly worded retraction in G&D, after legitimate questions by another group

A retraction appeared online last week in Genes & Development (G&D) that neatly brings together a few recent Retraction Watch threads: Whether retraction is appropriate for a failure to replicate, and whether retraction notices should give enough detail for readers to know what actually happened.

The retraction notice, for “Alternative splicing produces high levels of noncoding isoforms of bHLH transcription factors during development,” by Rahul N. Kanadia and Constance L. Cepko, reads: Continue reading The way science should work: A swift, clearly worded retraction in G&D, after legitimate questions by another group

The new math: How to up your citations (hint: duplication). Plus a correction for Naoki Mori

Here’s a good way to increase the number of times your work is cited: Publish studies three times.

On second (or third) thought, maybe not: The Journal of Steroid Biochemistry & Molecular Biology has retracted a pair of articles by three Japanese researchers who apparently liked their own work so much they decided to submit it, and submit it—and submit it again.

Here’s the notice for the first paper, a 2004 publication titled “Vitamin D receptor (VDR) promoter targeting through a novel chromatin remodeling complex,” by Shigeaki Kato, Ryoji Fujiki and Hirochika Kitagawa, fairly well-known molecular endocrinologists at the University of Tokyo: Continue reading The new math: How to up your citations (hint: duplication). Plus a correction for Naoki Mori

Update on Journal of Neuroscience retractions: Authors being investigated. Plus, editor explains why notices say nothing

We have updates on the two mysterious Journal of Neuroscience retractions we reported on yesterday. One is that we have learned that there is a university investigation into the work of one of the teams that retracted one of the studies. More on that in a bit.

Two, the journal’s editor, John Maunsell, responded to our request for comment, and we’re quoting his entire email (with annotation) because we think it raises important issues: Continue reading Update on Journal of Neuroscience retractions: Authors being investigated. Plus, editor explains why notices say nothing

Journal of Neuroscience retracts two, one 13 years old

The June 8 issue of the Journal of Neuroscience includes two retractions:

The notices are completely uninformative. They read: Continue reading Journal of Neuroscience retracts two, one 13 years old

So when is a retraction warranted? The long and winding road to publishing a failure to replicate

Sometime in 2009, the University of Nottingham’s Uwe Vinkemeier thought something was wrong with two papers he read in Genes & Development, one from 2006 and one from 2009. The papers claimed to show how changes to a protein called STAT1 affect programmed cell death. So he did what scientists are supposed to do: He tried to repeat the experiments, to replicate the results.

He couldn’t.

So he submitted the results to G&D, which was initially willing to publish the data along with a rebuttal by the original authors. But everyone seemed to be dragging their feet. Continue reading So when is a retraction warranted? The long and winding road to publishing a failure to replicate

On second thought: PNAS retracts two papers after results fail replication

The Proceedings of the National Academy of Sciences (PNAS) ran two retractions this week.

One of those papers was “Properdin homeostasis requires turnover of the alternative complement pathway,” which first appeared online in October of last year. The researchers were looking at the interaction between complement — a sort of primitive immune system — and a protein called properdin.

From the notice: Continue reading On second thought: PNAS retracts two papers after results fail replication

No confidence vote on sepsis paper data leads to Blood retraction

The journal Blood has retracted an article after the authors determined that they could not longer trust in the validity of the data.

The paper has been cited 22 times, according to Thomson Scientific’s Web of Knowledge. From the retraction notice:

Niessen F, Furlan-Freguia C, Fernández JA, Mosnier LO, Castellino FJ, Weiler H, Rosen H, Griffin JH, Ruf W. Endogenous EPCR/aPC-PAR1 signaling prevents inflammation-induced vascular leakage and lethality.

Blood. 2009;113(12):2859-2866.

The authors retract the 19 March 2009, paper cited above. Recently, the authors discovered that some primary data presented in this paper could not be independently reproduced. All coauthors concur with the retraction of the paper and apologize to the readers, reviewers, and editors of Blood for publishing these invalid data.

The nature of the data problem isn’t clear from that passage. But Blood editor Cynthia Dunbar told us that her journal Continue reading No confidence vote on sepsis paper data leads to Blood retraction

Four genetics papers retracted for duplication

Petter Portin, of the University of Turku, Finland, has been forced to retract four papers because they were duplicates of work he had already published.

Two of those retractions appear in the February 2011 issue of Hereditas. Here’s one retraction notice (link added):

The following article from Hereditas: Portin, P. ‘The effect of the mus309 mutation, defective in DNA double-strand break repair, on crossing over in Drosophila melanogaster suggests a mechanism for interference’, published online in Wiley Online Library (http://onlinelibrary.wiley.com/) on 1 September 2009, Hereditas, volume 146, pp. 162–176, has been retracted by agreement between the author, the Editor-in-Chief, Anssi Saura, and John Wiley & Sons A/S. The retraction has been agreed due to prior publication of a similar article in Genetica.

And the other (link added): Continue reading Four genetics papers retracted for duplication