by reason for retraction – Page 44

Pharma company demands retraction, damages in lawsuit against journal

A drug company that manufactures a painkiller used for surgery patients has sued an anesthesiology journal along with its editor and publisher and the authors of articles that it says denigrated its product unfairly.

In a complaint filed yesterday in U.S. District Court in New Jersey, Pacira Biosciences claims that “In the February 2021 issue of Anesthesiology, the ASA, reflecting a bias against EXPAREL amongst the editorial staff at Anesthesiology, published three articles, and other related content, that seriously disparage Pacira’s product EXPAREL,” an FDA-approved drug which they say is “a non-opioid pain medication proven to prolong post-surgery pain relief.”

In seeking retractions, compensatory and punitive damages exceeding $75,000 — the threshold for U.S. federal court — and lawyers’ fees, the company’s attorneys at Latham & Watkins write:

You want to do what? Paper on anal swabs for COVID-19 retracted for ethical issues

An article claiming that anal swabs can be used to detect SARS-CoV-2 in patients cured of Covid-19 has been retracted after the journal found that the authors failed to get permission from the patients to conduct the study.

To be clear: We’re not sure if the researchers — from Weihai Municipal Hospital, in Shandong, China — didn’t tell the patients they were taking anal swabs (which seems, well, unlikely) or that they didn’t tell them they would be using the results of the swabs in a study (the more reasonable interpretation). But the notice is vague on that point.

You may recall that in January the Chinese government in January launched a program to implement widespread anal swabbing to look for SARS-CoV-2 — a plan that, as the Washington Post reported, did not meet with cheers from the local population.

The article, “Anal swab as the potentially optimal specimen for SARS-CoV-2 detection to evaluate the hospital discharge of COVID-19 patients,” appeared in July in Future Microbiology. According to the abstract:

University in Japan revokes doctorate for plagiarism of text, image

A researcher in Japan has been stripped of his doctorate after a university investigation found that his thesis contained seven lines of plagiarized text and an image pulled from the internet without attribution.

Takuma Hara received his PhD in medical sciences from Tsukuba University in March 2019, writing a thesis about a genetic mutation’s role in certain brain tumors. Allegations of misconduct against Hara first emerged on April 6, 2020, according to a report released by the school.

The university launched an investigation, interviewed Hara and found that the thesis contained two plagiarized snippets: a microscopy image was pulled from the web without attribution and, on page 6, Hara took seven lines of text from a 2016 paper, titled “Clinicopathological features of craniopharyngioma and the endoscopic endonasal surgery,” published in a Japanese journal called Progress in Neuro-Oncology. The university revoked Hara’s degree last month.

Apparent HeLa cell line mixup earns a paper an expression of concern

A journal has issued an expression of concern for a 2011 paper after recognizing that the researchers may have been using contaminated cell lines.

The article, “Downregulation of NIN/RPN12 binding protein inhibit [sic] the growth of human hepatocellular carcinoma cells,” appeared in Molecular Biology Reports, a Springer Nature title. In it, the authors, from China Medical University Shengjing Hospital, sought to find:

whether the suppression of Nob1 by short hairpin RNA (shRNA) inhibits the growth of human hepatocellular carcinoma (HCC) cells. Recombinant lentiviral shRNA expression vector carrying Nob1 was constructed and then infected into human HCC cell line SMMC-7721

Perhaps they did, and the paper has been cited 21 times, according to Clarivate Analytics’ Web of Science. However, experimental lines of SMMC-7721 cells are among the many cell lines known to have been contaminated by HeLa cells, named for Henrietta Lacks — highly proliferative cervical cancer cells that have overrun labs worldwide. So perhaps they didn’t.

As the EoC states:

Journal of the paranormal has its first retraction

We should have seen this one coming. Or, maybe, they should have.

A journal dedicated to the study of psychics, the paranormal and related fringe research has its first retraction, according to the editor.

The Journal of Scientific Exploration says it detected plagiarism in a 2017 paper by Alejandro Parra, a well-known figure in the world of parapsychology — marking the first retraction from its pages.

The JSE publishes:

Dismissive reviews: A cancer on the body of knowledge

Observers describe the quantity of research information now produced variously as “torrent,” “overload,” “proliferation,” or the like. Technological advances in computing and telecommunication have helped us keep up, to an extent. But, I would argue, scholarly and journalistic ethics have not kept pace.

As a case in point, consider the journal article literature review. Its function is twofold: to specify where new information fits within the context of what is already known; and to avoid unknowingly duplicating research projects the public has already paid for. Paradoxically, however, information proliferation may discourage honest and accurate literature reviews. Research information accumulates, which increases the time required for conducting a thorough literature review, which increases the incentive to avoid it.

Most dismissive reviews that I have encountered are raw declarations. A scholar, pundit, or journalist simply declares that no research on a topic exists (or couldn’t be any good if it did exist). No mention is made of how or where (or, even if) they searched. Certain themes appear over and over, such as:

Meet the medical resident who had his wife peer review five of his papers

The pantheon of husband-wife teams in science includes Marie and Pierre Curie, Gerty and Carl Cori, even Ugur Sahin and Özlem Türeci, the founders of BioNTech, which collaborated with Pfizer on a Covid-19 vaccine.

To that list we hesitatingly add Ahmed Elkhouly and his spouse.

Elkhouly, a medical resident at St. Francis Medical Center, in Trenton, N.J., has lost five papers from the journal Cureus over a rather curious (ahem) domestic arrangement. According to the journal, Elkhouly used his unnamed wife as a peer reviewer on the articles, whose topics ranged from a case study on appendicitis to the neurological manifestations of COVID-19 infection.

Here’s the retraction notice for the COVID paper — which, by the way, raises our tally of retracted papers on the pandemic to 89:

Irony alert: stolen voices, relative rip-off

We’re always on the lookout for papers with that fillip of irony that lets us wonder if the Great Comedian in the Sky enjoys our little project. This week, we found two such articles.

One involves a 2008 paper in the Journal of Psycholinguistic Research titled “Examining Linguistic Relativity Hypothesis as One of the Main Views on the Relationship Between Language and Thought.” The author was Iman Tohidian, an Irani scholar. Except, in fact, the author was not Iman Tohidian, who appears to have what we might consider a rather appropriative view of the relationship between language and thought.

According to the retraction notice:

Drug researchers retract two papers, one because “human stem cells were actually mouse stem cells”

A group of drug researchers has lost a pair of 2020 papers for a lack of reproducibility and other problems, including the unfortunate mislabeling of murine stem cells as having come from humans. (In case you’re wondering, mouse and human stem cells are at once quite similar and highly divergent.)

One article, “Divergent synthesis of 5-substituted pyrimidine 2′-deoxynucleosides and their incorporation into oligodeoxynucleotides for the survey of uracil DNA glycosylases,” appeared in Chemical Science. The second, “Convenient synthesis of pyrimidine 2′-deoxyribonucleoside monophosphates with important epigenetic marks at the 5-position,” was published in Organic & Biomolecular Chemistry. Both journals belong to the Royal Society of Chemistry.

The senior author on the papers was Yana Cen, a medicinal chemist now at Virginia Commonwealth University in Richmond. Cen has not responded to a request for comment.

According to the abstract of the Chemical Science paper:

An author loses a fifth paper because it “bears the hallmarks of plagiarism”

A researcher in France has lost his fifth paper for plagiarism, this one a 2015 article on weakness in the elderly.

The study, “Identification of biological markers for better characterization of older subjects with physical frailty and sarcopenia,” appeared in Translational Neuroscience and came from a group in France led by Bertrand Fougère, of the Universitaire de Toulouse.

As we reported in 2019, Fougère had tallied previous retractions for plagiarism dating back to 2018. At the time, he told us:

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