‘The PubPeer conundrum:’ One view of how universities can grapple with a ‘waterfall of data integrity concerns’

As Retraction Watch readers no doubt know, PubPeer has played a key role in a growing number of cases of misconduct, allowing sleuths to publicly shine light in shadowy corners and prompting action by many universities. (Disclosure: Our Ivan Oransky is a volunteer member of the PubPeer Foundation’s board of directors.) But that has also meant that universities can feel overwhelmed by a deluge of PubPeer comments.

In a new article, three attorneys from Ropes & Gray in Boston who advise universities on such cases, along with Barbara Bierer, a researcher and former research integrity officer at the Brigham and Women’s Hospital, also in Boston, examine “the origins of PubPeer and its central role in the modern era of online-based scouring of scientific publications for potential problems and outlines the challenges that institutions must manage in addressing issues identified on PubPeer.” Attorneys Mark Barnes, Minal Caron and Carolyn Lye, and the Brigham’s Barbara Bierer, also recommend ways federal regulations could change to make the investigation process more efficient. We asked them to answer some questions about the article.

What prompted you to write this piece? 

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First-time scientific sleuths prompt nine retractions for neurosurgery group

René Aquarius

Two Dutch researchers were preparing a review of preclinical animal models for hemorrhagic stroke last July when they stumbled across a disturbing pattern in the literature. 

First, they found many more papers on the topic than the 50 or so they expected based on their experience: more than 600. 

Also, nearly every study proposed a different intervention, which was “very unusual,” said René Aquarius, a neurosurgery researcher at Radboud University Medical Center in the Netherlands. “Why would you show a very beneficial effect and then say, ‘let’s do something else?’” 

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Exclusive: Thousands of papers misidentify microscopes, in possible sign of misconduct

One in four papers on research involving scanning electron microscopy (SEM) misidentifies the specific instrument that was used, raising suspicions of misconduct, according to a new study. 

The work, published August 27 as a preprint on the Open Science Framework , examined SEM images in more than 1 million studies published by 50 materials science and engineering journals since 2010. 

Researchers found only 8,515 articles published the figure captions and the image’s metadata banners, both of which are needed to determine whether the correct microscope is listed in papers. Metadata banners usually contain important information about the experiments conducted, including the operating voltage of the microscope and the instrument’s model and parameters. 

Of these papers, 2,400 (28%) listed the wrong microscope manufacturer or model, raising questions about the integrity of the conducted research. 

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A journal editor said he’d retract a paper for plagiarism. A year later, it hasn’t happened.

Salvador Pineda

In June of last year, Salvador Pineda received an email from a researcher at Zhejiang University in China informing him one of his articles had been plagiarized. 

The researcher pointed Pineda to a paper, “A robust optimization method for optimizing day-ahead operation of the electric vehicles aggregator,” which appeared in Elsevier’s International Journal of Electrical Power and Energy Systems in November 2021. The article, by researchers at the University of Lahore, Pakistan, contained several figures copied from Pineda’s 2020 paper “An efficient robust approach to the day-ahead operation of an aggregator of electric vehicles,” as well as similar text.

Pineda, an associate professor of engineering at the University of Málaga in Spain, immediately wrote to the journal’s editor-in-chief, who said he’d retract the article, according to emails seen by Retraction Watch.

Yet the article remains intact, more than a year later, with the publisher blaming the delay on staffing changes at the journal.

Continue reading A journal editor said he’d retract a paper for plagiarism. A year later, it hasn’t happened.

A scientist peer-reviewed an article that plagiarized his work. Then he saw it published elsewhere.

Sam Payne

When Sam Payne reviewed a paper in March for Elsevier’s BioSystems, he didn’t expect to come across a figure he had created in his research. He quickly scrolled through the rest of the paper to find more figures, all copied from his work.

“It’s so blatant,” Payne, an associate professor of biology at Brigham Young University in Provo, Utah, posted on X

Although the journal rejected the paper at Payne’s recommendation, he worried the authors would try to publish elsewhere. 

“I had imagined they would just keep submitting it to new journals until it got accepted, because it was so brazenly plagiarized that they clearly didn’t care,” Payne told Retraction Watch.

Months later, Payne’s worry was justified. The paper, by researchers at First Moscow State Medical University, in Russia, appeared in Wiley’s Proteomics in May. 

Continue reading A scientist peer-reviewed an article that plagiarized his work. Then he saw it published elsewhere.

Authors retract quantum physics paper from Science after finding mistakes

A team of physicists has retracted a paper from Science after they discovered mistakes in their data and statistical analysis when following up on their work.

The paper “A room-temperature single-photon source based on strongly interacting Rydberg atoms” published in 2018, garnered 117 citations, according to Clarivate’s Web of Science. Of these, 97 citations came after the authors corrected the paper in 2020 to adjust for updated calibrations, which they said did not affect the conclusions of the article. 

This correction was unrelated to the reasons for retraction, said corresponding author Tilman Pfau, a professor of physics at the University of Stuttgart in Germany.

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Exclusive: Publisher to retract article for excessively citing one researcher after Retraction Watch inquiry

Muhammed Imam Ammarullah

A paper that cited a single researcher’s work in 53 of 64 references will be retracted following our inquiries, the publisher of the journal has told Retraction Watch. 

The article, ‘Culturally-informed for designing motorcycle fire rescue: Empirical study in developing country’, published in June in AIP Advances, overwhelmingly cites the work of Muhammed Imam Ammarullah, a lecturer at Universitas Pasundan in West Java, Indonesia, sometimes without obvious relevance to the text. 

An anonymous tipster came across the soon-to-be retracted paper on Google Scholar, then alerted the editors at AIP Advances in June to the strange citation pattern. The journal investigated, but didn’t acknowledge a problem with the excessive citations to Ammarullah’s work in their initial response to the complaint. Instead, they identified issues with six other, unrelated citations, according to emails seen by Retraction Watch. 

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Former Maryland dept. chair with $19 million in grants faked data in 13 papers, feds say

Richard Eckert

A former department chair engaged in research misconduct in work funded by 19 grants from the National Institutes of Health, according to the U.S. Office of Research Integrity. 

Richard Eckert, formerly the chair of the Department of Biochemistry and Molecular Biology at the University of Maryland, Baltimore, and deputy director of the university’s Marlene and Stewart Greenebaum Comprehensive Cancer Center, faked data in 13 published papers and two grant applications, ORI found. 

The ORI finding stated Eckert “engaged in research misconduct in research supported by” every NIH grant on which he served as principal investigator, totaling more than $19 million. The finding also lists multiple “Center Core Grants” worth hundreds of millions for shared resources and facilities at research centers. 

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What’s in a picture? Two decades of image manipulation awareness and action

This year marks the 20th anniversary of the publication of “What’s in a picture?  The temptation of image manipulation,” in which I described the problem of image manipulation in biomedical research. 

Two decades later, much has changed.  I am reassured by the heightened awareness of this issue and the numerous efforts to address it by various stakeholders in the publication process, but I am disappointed that image manipulation remains such an extensive problem in the biomedical literature. (Note: I use the term “image manipulation” throughout this piece as a generic term to refer to both image manipulation (e.g., copy/paste, erasure, splicing, etc.) and image duplication.)

In 2002, I was the managing editor of The Journal of Cell Biology (JCB), and STM journals were transitioning away from paper submissions.  We had just implemented online manuscript submission, and authors often sent figure files in the wrong file format.  One day, I assisted an author by reformatting some figure files.  In one of the Western blot image panels, I noticed sharp lines around some of the bands, indicating they had either been copied and pasted into the image or the intensity of those bands had been selectively altered.  

Mike Rossner

I vividly recall my reaction, which was, “Oh shit, this is going to be a problem.  We’re going to have to do something about this.”  With the blessing of then editor-in-chief, Ira Mellman, I immediately instituted a policy for the journal to examine all figure files of all accepted manuscripts for evidence of manipulation before they could be published.  We began using simple techniques, which I developed along with three of my colleagues at the time, Rob O’Donnell, Erinn Grady, and Laura Smith.  The approach involved visual inspection of each image panel using adjustments of brightness and contrast in Photoshop, to enhance visualization of background elements.  

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‘Violated’: Engineering professor found her name on four papers she didn’t write

Laura Schaefer

On a Friday in July, Laura Schaefer Googled herself to find her ORCID researcher ID for a paper submission. 

To her surprise, a paper popped up with her name in a journal she’d never published in. Her surprise quickly turned to concern – had someone copied one of her articles? 

As she searched the site where the work appeared, she found more articles with her name, covering subjects she had never written about and with co-authors she didn’t know. 

“[I] became angrier the more I found, and also started feeling really violated that someone had used my name and title to put forward something that wasn’t scientifically rigorous,” Schaefer, a professor of mechanical engineering at Rice University in Houston, said.

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