Cardiff University looking into allegations of misconduct by group headed by its dean of medicine

Last December, we reported on a Journal of Immunology paper that was retracted after a Cardiff University investigation found the senior author had inappropriately manipulated images.  The inquiry found that there had been “no intention to mislead and subsequent repeats of the original experiments have shown that the paper’s conclusions remain sound,” the university told us at that time.

The senior author of the paper, Rossen Donev, had since moved on to the University of Swansea, and Cardiff had notified the Medical Research Council, which funded the work. The case seemed to end there.

But other work by Donev’s former lab group, which is led by BP Morgan, the dean of Cardiff’s medical school, has been the subject of scrutiny by at least one anonymous whistleblower. That whistleblower’s allegations — which also center on image manipulation — have been reported on the relatively new site Science Fraud, which posts allegations anonymously. They involve papers published in Cancer Research, Molecular Immunology, and the American Journal of Physiology.

We’ve now learned that Cardiff has “initiated its Procedure for Dealing with Allegations of Academic Misconduct in Research” after Clare Francis, another anonymous whistleblower whose name will probably be familiar to Retraction Watch readers, forwarded the concerns to university officials. Now, according to an email from Carole A Evans, Cardiff’s Director of Governance and Compliance Division: Continue reading Cardiff University looking into allegations of misconduct by group headed by its dean of medicine

Transparency in action: EMBO Journal detects manipulated images, then has them corrected before publishing

As Retraction Watch readers know, we’re big fans of transparency. Today, for example, The Scientist published an opinion piece we wrote calling for a Transparency Index for journals. So perhaps it’s no surprise that we’re also big fans of open peer review, in which all of a papers’ reviews are made available to readers once a study is published.

Not that many journals have taken this step — medical journals at BioMedCentral are among those that have, and they even include the names of reviewers — but a recent peer review file from EMBO Journal, one publication that has embraced this transparent approach, is particularly illuminating.

Alan G. Hinnebusch, of the U.S. Eunice Kennedy Shriver National Institute of Child Health and Human Development, submitted a paper on behalf of his co-authors on November 2, 2011, at which point it went out for peer review. The editors sent those reviews back to the author on January 2, 2012, and Hinnebusch responded with revisions on April 4. So far, the process looks much like that any scientist goes through — questions about methods, presentation, and conclusions, followed by answers from the authors.

But what caught the eye of frequent Retraction Watch commenter Dave, who brought this to our attention, was what happened starting on May 18 when the editors responded to the authors again. (That letter is labeled as page 6, but is actually page 16 of the linked document.): Continue reading Transparency in action: EMBO Journal detects manipulated images, then has them corrected before publishing

Canada’s Memorial U says “substantial data misrepresentation” described by retraction notice was unintentional

Yesterday, we reported on a retraction in the Journal of Neuroscience for “substantial data misrepresentation.” When we posted, the authors’ institution, Memorial University in Newfoundland, Canada, had not been able to respond to our questions yet, because of the long Canada Day weekend. This morning, they sent us the following statement, which describes the errors that led to the retraction as unintentional: Continue reading Canada’s Memorial U says “substantial data misrepresentation” described by retraction notice was unintentional

Controversial paper on life-extending buckyballs corrected after blog readers note problems

Back in April, a group of French and Tunisian researchers published a paper in Biomaterials which came to the astonishing conclusion that buckyballs (carbon tetrachloride) coated in olive oil could dramatically extend the lives of lab rodents. That news was picked up by Derek Lowe’s In the Pipeline blog, on which he expressed some bemusement about the work but ultimately praised it:

These are reasonable (but unproven) hypotheses, and I very much look forward to seeing this work followed up to see some more light shed on them. The whole life-extension result needs to be confirmed as well, and in other species. I congratulate the authors of this work, though, for giving me the most number of raised eyebrows I’ve had while reading a scientific paper in quite some time.

One of those eyebrows dropped a bit the following day, when Lowe reported that readers had pointed him to a clear case of image duplication in the article. At the time, Lowe concluded: Continue reading Controversial paper on life-extending buckyballs corrected after blog readers note problems

Shikeagi Kato, who resigned post in March, retracts Nature paper

Shikeagi Kato, an endocrinologist formerly of the University of Tokyo who resigned on March 31 amidst an investigation into his work, has retracted another paper, this one in Nature.

Here’s the notice for “DNA demethylation for hormone-induced transcriptional derepression,” which was the subject of a correction last October: Continue reading Shikeagi Kato, who resigned post in March, retracts Nature paper

Korean stem cell investigation expands to another researcher, and more papers

Last month, we brought you the story of Soo-Kyung Kang, a Seoul National University stem cell researcher who has now retracted four papers amidst questions about image manipulation in a total of 14 studies. That story has drawn a great deal of attention in Korea, with comparisons to the Woo-Suk Hwang scandal, and has even led to a profile of Retraction Watch in the Seoul Daily, one of Korea’s largest newspapers.

We’ve now learned that the investigation has grown to 25 papers after an anonymous whistleblower warned about possible data fabrications in another paper by Kang, an associate professor of veterinary biotechnology, and Kyung-Sun Kang, director of the Adult Stem Cell Research Center in the same department (but no relation). And Soo-Kyung Kang was investigated in 2010, according to the Korea Herald.

The researchers’ labs are also under lockdown Continue reading Korean stem cell investigation expands to another researcher, and more papers

Two new corrections for Utah group that retracted two Cell Metabolism papers for missing notebooks

We have an update on the case of a University of Utah lab that retracted two Cell Metabolism papers last month after a fired lab technician disposed of two lab notebooks without permission. The team has now corrected two other papers, one in Blood and the other in the Journal of Clinical Investigation.

Here’s the notice from Blood: Continue reading Two new corrections for Utah group that retracted two Cell Metabolism papers for missing notebooks

Retraction count for resveratrol researcher Dipak Das rises to 12

Das, via UConn

Dipak Das, the UConn researcher whom the university earlier ths year found to have fabricated or falsified data more than 100 times, has four more retractions to his name.

The notices appear in the June 1, 2012 issue of the American Journal of Physiology: Heart and Circulatory Physiology, and suggest that Das was not all that cooperative: Continue reading Retraction count for resveratrol researcher Dipak Das rises to 12

Why retraction notices matter: Group’s repeated misuse of figures gets different play from five journals

For some journals, thorough retraction notices are the rule — and, when misconduct is involved, the price authors pay for abusing the trust of the editors and the readers. Others seem to take a more casual approach. Guess which we think is best.

Consider the case of a group of researchers in China led by Tan Jinquan, an immune system expert at Wuhan University. Over the past two years or so, Jinquan and colleagues have lost no fewer than a half-dozen papers containing evidence of image manipulation. But, depending on the journal pulling the articles, you might not know it.

Continue reading Why retraction notices matter: Group’s repeated misuse of figures gets different play from five journals

Authors retract two Cell Metabolism papers after “data were inappropriately removed from the laboratory”

A group of researchers at the University of Utah has retracted two papers from Cell Metabolism after they realized that a dismissed employee had tossed out data that were the basis of some error-laden figures.

Here’s the notice for both papers: Continue reading Authors retract two Cell Metabolism papers after “data were inappropriately removed from the laboratory”