Category: expression of concern

Canadian researchers in legal battle over investigation object to third retraction

The Journal of Clinical InvestigationA third retraction — and a notice of concern — have emerged from the investigation into a husband and wife research team at the University of Toronto that found evidence of faked images and duplicated data.

The problem, according to the latest retraction note for Sylvia Asa and Shereen Ezzat, in the Journal of Clinical Investigation: Portions of the RT-PCR gels “are duplicated in this publication and in a subsequent publication.” That subsequent publication is a 2003 paper that has received a Notice of Concern from the American Journal of Pathology.

According to the retraction note, co-author Gillian E. Wu of York University signed off on the journal’s decision, but Asa, Ezzat and second author Lei Zheng dissented to the retraction. Third author Xian-Feng Zhu couldn’t be reached. Although corresponding author Asa noted that “the initial screen of these samples support the conclusions made in the paper,” the JCI made its position perfectly clear in the note:

Continue reading Canadian researchers in legal battle over investigation object to third retraction

“Significant overlap” between figures spurs note of concern for 13-year-old retinoblastoma paper

AmJPatholThe American Journal of Pathology has posted a note of concern to a 2002 paper about retinoblastoma after discovering two sets of figures “share significant overlap… suggesting that they did not originate from different specimens.”

The overlap was “simultaneously brought to the attention of the Editors” by both the corresponding author and a “concerned reader.”

The paper examined the role of a transcription factor called NF-kappaB in driving retinoblastoma, and suggested that inhibiting the molecule’s activity could be a therapeutic strategy.

The authors attribute the overlap to “an inadvertent misidentification of the original files at the stage of image capture.” They add that they “sincerely regret this inadvertent error;” because other data in the paper show “concordant results,” they stand by the paper’s findings.

Here’s the note:

Continue reading “Significant overlap” between figures spurs note of concern for 13-year-old retinoblastoma paper

JAMA vitamin-hip fracture study earns Expression of Concern for integrity issues

jama coverJAMA has issued an Expression of Concern about a 2005 study of whether two different types of vitamin B could prevent broken hips in people who’d suffered strokes.

The original study concluded:

In this Japanese population with a high baseline fracture risk, combined treatment with folate and vitamin B12 is safe and effective in reducing the risk of a hip fracture in elderly patients following stroke.

Here’s the notice for the study, “Effect of folate and mecobalamin on hip fractures in patients with stroke: a randomized controlled trial:” Continue reading JAMA vitamin-hip fracture study earns Expression of Concern for integrity issues

Author retracts study of changing minds on same-sex marriage after colleague admits data were faked

science coverIn what can only be described as a remarkable and swift series of events, one of the authors of a much-ballyhooed Science paper claiming that short conversations could change people’s minds on same-sex marriage is retracting it following revelations that the data were faked by his co-author.

[3:45 p.m. Eastern, 5/28/15: Please see an update on this story; the study has been retracted.]

Donald Green, of Columbia, and Michael LaCour, a graduate student at UCLA, published the paper, “When contact changes minds: An experiment on transmission of support for gay equality,” in December 2014. The study received widespread media attention, including from This American Life, The New York Times, The Wall Street Journal, The Washington Post,  The Los Angeles Times, Science Friday, Vox, and HuffingtonPost, as LaCour’s site notes.

David Broockman and Joshua Kalla, graduate students at University of California, Berkeley, were two of the people impressed with the work, so they planned an extension of it, as they explain in a timeline posted online yesterday: Continue reading Author retracts study of changing minds on same-sex marriage after colleague admits data were faked

Expression of concern opens floodgates of controversy over lead in water supply

journal-awwa-cover-feb-2015An expression of concern has been published on a paper that taps into a decades-long fight over how to remove lead from the water supply.

The paper in question, published in the Journal American Water Works Association, supports the safety of a common but frequently criticized way of incrementally removing lead pipes. The expression of concern came after years of back-and-forth  letters to the editor between other scientists and the authors.

Lead water pipes have been causing lead poisoning for generations; some people have even theorized that the ancient Romans’ use of the metal facilitated the empire’s downfall. The dangers of childhood exposure to lead — delayed development, irreversible damage to the brain and nervous system and behavioral problems — have been documented in the U.S. since the 1940s, but the Environmental Protection Agency didn’t start regulating lead levels in drinking water until 1991, when the “lead and copper rule” went into effect. That set the standard for utility companies’ lead testing: if 10 percent or more of samples from homes had lead levels above 15 parts per billion, the companies were required to replace 7% of their lead pipes a year until they met the requirements.

Continue reading Expression of concern opens floodgates of controversy over lead in water supply

Researcher loses second bid to quash Diabetes expressions of concern

Mario Saad, via unicamp.br
Mario Saad, via unicamp.br

It hasn’t been a good week for scientists going to court to silence criticism of their work.

Yesterday, PubPeer won a near-complete victory in a case seeking the identities of their commenters. And also yesterday, a Massachusetts judge struck down — for the second time — a request by Mario Saad to remove expressions of concern about four of his papers in Diabetes.

In his ruling, Judge Timothy Hillman wrote: Continue reading Researcher loses second bid to quash Diabetes expressions of concern

Diabetes researcher won’t give up court fight to quash expressions of concern

Mario Saad, via unicamp.br
Mario Saad, via unicamp.br

Apparently, you can’t keep Mario Saad down.

The researcher, who had 12 figures in a paper corrected this week, was dealt a setback last week when a judge denied his motion to remove expressions of concern on four of his papers in the journal Diabetes, saying that would have amounted to prior restraint — essentially, censorship (a no-no, thanks to the First Amendment).

Saad and his attorneys, however, were undeterred. They filed a motion for reconsideration just four days later, along with a brief, arguing: Continue reading Diabetes researcher won’t give up court fight to quash expressions of concern

Judge denies motion by researcher to quash Diabetes expressions of concern

Mario Saad, via unicamp.br
Mario Saad, via unicamp.br

American Diabetes Association 1, Mario Saad 0.

As reported by the National Law Journal, a federal judge in Boston has denied Saad’s requests to stop the ADA’s flagship journal, Diabetes, from publishing expressions of concern about four of Saad’s papers, and to prevent the journal from retracting the studies.

Saad filed suit against the ADA on February 5. Judge Timothy Hillman wrote in his order yesterday that approving the researcher’s motion would have violated the right to free speech: Continue reading Judge denies motion by researcher to quash Diabetes expressions of concern

Frontiers lets HIV denial article stand, reclassifies it as “opinion”

frontiers phFollowing an investigation sparked by criticism for its decision to publish a paper questioning the link between HIV and AIDS, a Frontiers journal has decided to not retract the article but rebrand it as an “opinion.”

In September, 2014, Patricia Goodson, a professor of health education at Texas A&M University, published an article called “Questioning the HIV-AIDS hypothesis: 30 years of dissent.”

The paper was quickly called into question, and the journal, Frontiers in Public Health, issued a statement of concern and promised to look into the problem. Now, they’ve announced their solution: call the paper an “opinion” and publish an argument against it.

Continue reading Frontiers lets HIV denial article stand, reclassifies it as “opinion”

Publisher and uni go head to head over disputed images in diabetes papers

Mario Saad, via unicamp.br
Mario Saad, via unicamp.br

The State University of Campinas University of Campinas and the American Diabetes Association disagree strongly over how to handle disputed images from faculty member Mario Saad, who is suing the ADA to prevent retraction of his papers.

While the State University of Campinas University of Campinas (Unicamp) acknowledges that 2 of Saad’s papers contain “mistakes”, it concluded there was “not an intention in the actions of the authors,” and the mistakes did not have a negative impact on the scientific community. Ultimately: “the studies published have their own strength, are healthy and were not artificially strengthened by the incorrect images.”

In response, however, Saad’s lawsuit says the ADA asked the school to reinvestigate the articles, and refused to accept any papers from Unicamp faculty in any ADA journals until the issues are resolved.

The ADA has issued four expressions of concern in Saad’s research published in its flagship journal, Diabetes. Saad’s lawsuit aims to prevent the journal from retracting those papers, and asks for monetary compensation.

Retraction Watch has obtained a report of the investigation by Unicamp and Saad’s lawsuit. You can read the full lawsuit here, and the investigation report here.

Here is an excerpt from the Unicamp’s findings: Continue reading Publisher and uni go head to head over disputed images in diabetes papers