The authors of a 2020 paper in Cell are earning plaudits after they retracted the study following the publication of an article last year that contradicted their earlier findings.
The paper, “Allosteric Activators of Protein Phosphatase 2A Display Broad Antitumor Activity Mediated by Dephosphorylation of MYBL2,” purported to show that a particular compound could be useful in animal studies because it did not have some of the off-target activity of other compounds. It has been cited 45 times, according to Clarivate’s Web of Science.
But as the retraction notice says, a paper published last year in The EMBO Journal by Jakob Nilsson and Gianmatteo Vit of the University of Copenhagen and colleagues found that wasn’t true:
Continue reading Doing the right thing: Harvard researchers retract Cell paper after work contradicts finding